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Riachy M.A.,Hotel Dieu de France Hospital
BMJ case reports | Year: 2012

The authors present the case of a 72-year-old patient who presented with severe dyspnoea, scant haemoptysis, pronounced desaturation and bilateral haematomas on the upper limbs. Chest radiography showed bilateral infiltrates mainly in the lower lobes. The patient's prothrombin time, and platelet count were normal. However, the activated partial thromboplastin time showed a prolongation that was not reversed on a correction study. Factor VIII (FVIII) levels were very low and evidence of FVIII inhibitor was found. The patient had started taking ivabradine 2 months earlier, and the diagnosis of idiosyncratic acquired haemophilia was established. The patient was treated with volume expansion therapy, high levels of oxygen, multiple transfusions, methylprednisolone, desmopressine and rituximab. On the 3rd day, the patient showed progressive amelioration of his dyspnoea, oxygen needs and chest infiltrates. On the 7th day, the patient was discharged. Source

Riachy M.A.,Hotel Dieu de France Hospital
BMJ case reports | Year: 2011

The authors present the case of a 43-year-old male who presented at the emergency department, with a mean arterial pressure of 48 mm of Hg, a sinus tachycardia of 142/min and shallow breathing at 30/min. Two days previously, he started a high-grade fever with a concomitant reddish and painful left knee and right elbow, without any treatment. Septic shock was diagnosed and the patient was started on empiric antibiotics combining ceftriaxone and vancomycin and vasopressors (norepinephrine). The painful knee and elbow joints were aspirated and cultures grew Streptococcus pneumoniae. The patient's clinical condition improved progressively and after investigation, the diagnosis of multiple myeloma was concluded. Pneumococcal septic arthritis, an extraordinary cause of septic arthritis, is a manifestation of an underlying disease and can be responsible for septic shock. Its diagnosis should direct further investigations. It can occur in patients with joint disease but should emphasise the search of systemic immunosuppression. Source

Noun P.,Saint George University Hospital | Noun P.,Notre Dame University - Louaize | Djambas-Khayat C.,Hotel Dieu de France Hospital
Journal of Pediatric Hematology/Oncology | Year: 2012

Children with cancer suffer a lot, especially those in developing countries with limited health resources. Although pediatric hematology/oncology has become a well-developed subspecialty in Lebanon, pediatric palliative care is still underrecognized. The current pediatric hematology/oncology and palliative care services in Lebanon are reviewed in this article. We stress upon the adverse consequences of absence of well-defined pediatric palliative care in order for it to be recognized and integrated as a new discipline. Copyright © 2012 by Lippincott Williams & Wilkins. Source

Khalil R.B.,Psychiatric Hospital of the Cross | Hachem D.,Psychiatric Hospital of the Cross | Richa S.,Hotel Dieu de France Hospital
Eating and Weight Disorders | Year: 2011

OBJECTIVE: To understand the comorbidity of schizophrenia and eating disorders (ED) in male patients. METHOD: A review of the published literature was made via Med- Line using the following terms: "schizophrenia" or "psychosis" in association with "eating disorders", "anorexia nervosa", "binge eating" or "bulimia nervosa", in association with the terms "comorbidity" or "comorbidities" and finally in association with the term "male", "man" or "men". RESULTS: Groups of male patients known to suffer from schizophrenia and screened for ED suffer essentially from anorexia nervosa (0.81%). Groups of male patients screened for anorexia nervosa and then for schizophrenia demonstrate high comorbidity prevalence (36%). In general, ED symptoms diminish with psychotic episodes and recur when the psychotic episode remits. A man with an ED has a 3.6 times more risk than a woman with an ED to have comorbid schizophrenia. In men, ED present atypical features so that ED not otherwise specified (EDNOS) is relatively frequent. DISCUSSION AND CONCLUSION: Male patients described in the literature as suffering from schizophrenia and ED fall under one of four categories: a) acute psychotic episode related to organic causes due to malnutrition; b) male patients presenting with an ED who later develops schizophrenia; c) male patients known to suffer from schizophrenia and who develops distorted eating cognitions and disordered behaviors; d) male patients suffering from schizophrenia and developing a medication-induced ED. ©2011, Editrice Kurtis. Source

Baddoura R.,Hotel Dieu de France Hospital | Hoteit M.,American University of Beirut | El-Hajj Fuleihan G.,American University of Beirut
Journal of Clinical Densitometry | Year: 2011

The purpose was to report on the burden of osteoporotic fractures in the Eastern Mediterranean Region (EMR) and the use of bone mineral density (BMD) dual-energy X-ray absorptiometry (DXA) databases for osteoporosis diagnosis. PubMed electronic database was reviewed using the following MeSH terms: "Hip fractures," "Fractures, Compression," "Radius Fractures," "Osteoporosis," "Bone density," and "Middle East" up to July 2009. Incidence of hip fractures varied across the EMR between 100 and 295 per 100,000 person-years in women and 71 and 200 per 100,000 person-years in men. No data were found on other nonvertebral osteoporotic fractures. Prevalence of radiographic vertebral fractures older than 65. yr ranged between 15% and 25% in women and 7.3% and 18% in men. By 2020, the number of hip fractures older than 50. yr would increase by 20%. DXA manufacturer's reference curves for the spine were higher than population-specific ones. At the hip, National Health and Nutrition Examination Survey (NHANES) and population-based curves were comparable. Estimates of the relative risk of vertebral fracture per SD decrease in BMD using NHANES and local data set were similar, that is, 1.61 (1.17-2.23) and 1.49 (1.14-1.95), respectively. The EMR is similar to southern Europe regarding incidence rates of hip fracture, suggesting the health burden to be significant. Using DXA at the hip, population-specific reference databases did not perform better than NHANES on which the FRAX model has been developed highlighting the need for reviewing fracture risk assessment strategies in the EMR. © 2011. Source

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