Rodrigues F.F.,Federal University of Grande Dourados |
Correa L.F.,Federal University of Grande Dourados |
De Arruda T.B.,Federal University of Grande Dourados |
Casulari L.A.,Hospital Universitario Of Brasilia
Ethnicity and Disease | Year: 2011
Objective: To evaluate the prevalence of metabolic syndrome in an indigenous Brazilian population. Methods: Indigenous Brazilians aged 18- 69 years from Jaguapiru Village, Dourados, MS were studied. Participants were selected by simple random sampling of 360 houses in the village. The abdominal circumference of the population was evaluated, and measurements <80 cm for females or <90 cm for males were considered normal. Capillary blood glucose levels by glucometer and oral glucose tolerance tests were measured, and, when necessary, total cholesterol, HDL cholesterol and triglyceride levels were assessed. Results: Of the 632 indigenous Brazilians in the study, 281 were males. We observed that 287 (45.4%) presented abdominal circumference values greater than normal; of those, 199 were women (43.4% of all women in the study) and 88 were men (26.1% of all men in the study). Conclusion: Metabolic syndrome is common in the Indian Jaguapiru Village.
PubMed | Secretaria de Saude do Distrito Federal, Pontifical Catholic University of Goiás, Hospital Universitario Of Brasilia and University of Brasilia
Type: | Journal: Revista brasileira de anestesiologia | Year: 2016
Sevoflurane is often used in pediatric anesthesia and is associated with high incidence of psychomotor agitation. In such cases, dexmedetomidine (DEX) has been used, but its benefit and implications remain uncertain. We assessed the effects of DEX on agitation in children undergoing general anesthesia with sevoflurane.Meta-analysis of randomized clinical and double-blind studies, with children undergoing elective procedures under general anesthesia with sevoflurane, using DEX or placebo. We sought articles in English in PubMed database using the following terms: Dexmedetomidine, sevoflurane (Methyl Ethers/sevoflurante), and agitation (Psychomotor Agitation). Duplicate articles with children who received premedication and used active control were excluded. It was adopted random effects model with DerSimonian-Laird testing and odds ratio (OR) calculation for dichotomous variables, and standardized mean difference for continuous variables, with their respective 95% confidence interval (CI).Of 146 studies identified, 10 were selected totaling 558 patients (282 in DEX group and 276 controls). The use of DEX was considered a protective factor for psychomotor agitation (OR=0.17; 95% CI 0.13 to 0.23; p<0.0001) and nausea and vomiting in PACU (OR=0.49; 95% CI 0.35 to 0.68; p<0.0001). Wake-up time and PACU discharge time were higher in the dexmedetomidine group. There was no difference between groups for extubation time and duration of anesthesia.Dexmedetomidine reduces psychomotor agitation during wake-up time of children undergoing general anesthesia with sevoflurane.
Adami Y.L.,Instituto Oswaldo Cruz Fiocruz |
Adami Y.L.,Federal University of Fluminense |
Rodrigues G.,Instituto Oswaldo Cruz Fiocruz |
Alves M.C.,Instituto Oswaldo Cruz Fiocruz |
And 3 more authors.
Memorias do Instituto Oswaldo Cruz | Year: 2014
Mansonella ozzardi infections are common in the riverside communities along the Solimões, Negro and Purus Rivers in the state of Amazonas (AM). However, little is known about the presence of this parasite in communities located in regions bordering AM and the state of Acre. The prevalence rate of M. ozzardi infections was determined in blood samples from volunteers according to the Knott method. A total of 355 volunteers from six riverine communities were enrolled in the study and 65 (18.3%) were found to be infected with M. ozzardi. As expected, most of the infections (25%) occurred in individuals involved in agriculture, cattle rearing and fishing and an age/sex group analysis revealed that the prevalence increased beginning in the 40-50-years-of-age group and reached 33% in both sexes in individuals over 50 years of age. Based on the described symptomatology, articular pain and headache were found to be significantly higher among infected individuals (56 and 65% prevalence, respectively, p < 0.05). Sera from volunteers were subjected to ELISA using a cocktail of recombinant proteins from Onchocerca volvulus to evaluate the specificity of the test in an endemic M. ozzardi region. No cross-reactions between M. ozzardi-infected individuals and recombinant O. volvulus proteins were detected, thus providing information on the secure use of this particular cocktail in areas where these parasites are sympatric.
Felli V.E.A.,University of Sao Paulo |
da Silva E.J.,University of Brasilia |
Torri Z.,University of Brasilia |
Abreu A.P.,University of Brasilia |
Branco M.T.A.,Hospital Universitario Of Brasilia
Revista Latino-Americana de Enfermagem | Year: 2013
Objective: To analyze the workloads, strain processes and sickness absenteeism among nursing workers from a teaching hospital in the Brazilian Central-West. Method: A descriptive and cross-sectional study was developed with a quantitative approach, based on the theoretical framework of the social determination of the health-disease process. Data were collected between January and December 2009, based on records of complaints related to occupational exposure among nursing professionals, filed in the software Monitoring System of Nursing Workers' Health. For the sake of statistical analysis, relative and absolute frequencies of the variables and the risk coefficient were considered. Results: 144 notifications of occupational exposure were registered across the analysis period, which represented 25% of the total nursing population at the hospital. The physiological and psychic workloads were the most representative, corresponding to 37% and 36%, respectively. These notifications culminated in 1567 days of absenteeism for disease treatment. Conclusions: The findings evidence the impact of occupational illnesses on the absenteeism of nursing workers, and can be used to demonstrate the importance of institutional investments in occupational health surveillance. © 2013 Revista Latino-Americana de Enfermagem.
Santos F.S.,University of Sao Paulo |
Santos F.C.,Hospital Universitario Of Brasilia |
Santos L.H.,Federal University of Maranhão |
Leite A.M.,University of Sao Paulo |
Mello D.F.,University of Sao Paulo
Einstein (São Paulo, Brazil) | Year: 2015
OBJECTIVE: To identify, in national and international journals, the studies conducted in Brazil related to breast feeding and reducing cases of diarrhea in children under 2 years of age, featuring health interventions more used.METHODS: Descriptive study, based on an integrative review of literature from PubMed and LILACS data published between January 1992 and August 2011. The keywords "breastfeeding AND diarrhea" was searched in Portuguese, English and Spanish in PubMed and LILACS. The guiding question was: "What was knowledge produced about breast feeding and prevention of diarrhea in children under 2 years between 1992 and 2011 in studies conducted in Brazil?"RESULTS: We selected 11 studies that showed the importance of breast feeding in the prevention and protection against diarrhea in children under 6 months, especially among children in exclusive breastfeeding.CONCLUSION: Public health policies should be directed to the context of each locality, in order to reduce the problems that involve the early weaning.
Vasconcelos D.F.,University of Brasilia |
Vasconcelos D.F.,Hospital Universitario Of Brasilia |
Junqueira Junior L.F.,University of Brasilia |
Junqueira Junior L.F.,Hospital Universitario Of Brasilia
Arquivos Brasileiros de Cardiologia | Year: 2012
Background: The association of variably altered cardiac autonomic and ventricular systolic and diastolic functions is still controversial and little explored in chronic Chagas' disease. Objective: To evaluate the extent to which cardiac autonomic and mechanical ventricular functions are altered and whether they are associated in asymptomatic chagasic cardiomyopathy. Methods: A total of 13 patients with asymptomatic chagasic cardiomyopathy and 15 normal subjects (control group) were evaluated and the autonomic modulation of heart rate variability for five minutes, in the temporal and spectral domains, in the supine and orthostatic positions, as well as ventricular function based on morphological-functional variables obtained by Doppler echocardiography were correlated. Statistical analysis used the Mann-Whitney test and Spearman's correlation. Results: In both positions, the temporal indexes (p = 0.0004 to 0.01) and total (p = 0.0007-0.005) and absolute spectral areas, of low and high frequencies (p = 0.0001 to 0.002), were lower in the chagasic group. The vagal-sympathetic balance was similar in the two groups in both positions (p = 0.43 to 0.89). The echocardiographic variables did not differ between groups (p = 0.13 to 0.82), except the left ventricular end-systolic diameter, which was larger (p = 0.04) and correlated directly with reduced rates of global (p = 0.01 to 0.04) and parasympathetic (p = 0.002 to 0.01) autonomic modulation in patients with Chagas disease in the orthostatic position. Conclusion: The sympathetic and parasympathetic depressions with preserved balance were associated with only one ventricular dysfunction indicator. This suggests that cardiac autonomic dysfunction may precede and be independently more severe than ventricular dysfunction, with no causal association between both disorders in chronic chagasic cardiomyopathy.
Sousa J.B.,Hospital Universitario Of Brasilia
Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery | Year: 2012
Proficiency and competence of endoscopists is perhaps the mainstay of successful diagnostic and therapeutic colonoscopy. To analyze indications, diagnostic findings, and complications of colonoscopies performed by resident physicians in a university teaching hospital. Were analyzed 1,000 colonoscopies consecutively performed by fourth-year residents under direct supervision of experienced colonoscopists. Information on patients' demographic data, bowel preparation, indications for the procedure, success of the procedure, diagnostic findings, and complications were obtained. A total of 596 (59.6%) female and 404 (40.4%) male patients were examined. Age ranged from 3 to 99 years (mean 53.8 years). Bowel preparation was performed with 10% mannitol solution in 978 patients (97.8%), being considered appropriate in 97.6% of cases. Main indications were: diagnosis (56.4%), therapy (9.6%), screening (17.3%), and surveillance (22%). Cecal and ileocecal valve intubation rates were 90.3 and 58.6%, respectively. Colonoscopy was normal in 45.8% of cases. The most common diagnosis was diverticulosis (18.5%), followed by polyps (17%) and malignancies (6.8%). Findings consistent with an inflammatory process were identified in 122 patients (12.2%) and vascular abnormalities were detected in 11 patients (1.1%). Other diagnoses accounted for 3.9% of cases. There were two cases (0.2%) of complications (submucosal hematoma and bleeding), both after polypectomy, with no need for surgical intervention. The residents under supervision and guidance of specialists can perform colonoscopies with excellent success and low complication rates, with final results comparable to those achieved by fully trained endoscopists.
Lobo M.E.,Hospital Universitario Of Brasilia
BMJ case reports | Year: 2010
Stiff-person syndrome (SPS) is a rare neurological condition consisting of progressive and fluctuating rigidity of the axial muscles combined with painful spasms. The pathophysiology of SPS is not fully understood, but there seems to be an autoimmune component. The use of rituximab, a chimeric monoclonal antibody targeting CD20 protein in the surface of mature B cells, for the treatment of SPS is a recent therapeutical approach showing promising results. The authors present a case report of a 41-year-old female patient diagnosed with SPS who was treated with rituximab in a public hospital in Brasília, Brazil, showing a good and safe response to the treatment so far. Our data go along with some recent articles published in the literature.
Depression with postpartum onset: A prospective cohort study in women undergoing elective cesarean section in Brasilia, Brazil [Depressão com início após o parto: Estudo de corte prospectivo em mulheres submetidas à cesárea eletiva em Brasília,Brasil]
Zaconeta A.M.,University of Brasilia |
De Queiroz I.F.B.,Hospital Universitario Of Brasilia |
Amato A.A.,University of Brasilia |
Da Mottal L.D.C.,University of Brasilia |
Casulari L.A.,University of Brasilia
Revista Brasileira de Ginecologia e Obstetricia | Year: 2013
PURPOSE: It was to determine the prevalence of depressive symptoms in a sample of puerperal women from Brasília, Brazil, distinguishing cases with onset after delivery from those already present during pregnancy. METHODS: A prospective cohort study with convenience sampling of patients submitted to elective cesarean section at two private hospitals. As an instrument for assessing depressive symptoms, the Edinburgh Postnatal Depression Scale with cutoff ≥13 was applied shortly before delivery and four to eight weeks after childbirth. RESULTS: Among the 107 women who completed the study, 11 (10.3%) had significant depressive symptoms during pregnancy and 12 (11.2%) during the postpartum period. Among the 12 patients with postpartum symptoms, 6 had symptoms during pregnancy, so that 5.6% of the sample had postpartum onset of depression. The higher overall frequency of depression was significantly among single women than among married women (p=0.04), a fact mainly due to a higher frequency of single women experiencing persistent depressive symptoms both before and after delivery (p=0.002). The risk of depression was not influenced by age, parity or educational level. CONCLUSION: Women with depression identified during the postpartum period comprise a heterogeneous group, in which symptoms may have started before pregnancy, during pregnancy or after childbirth. In this sample, half of the postpartum depression cases already presented symptoms during late pregnancy. Since depression can arise before and after childbirth, it may have different etiologies and, therefore, a different response to treatment, a possibility that should be considered by clinicians and researchers.
PubMed | Hospital Universitario Of Brasilia and University of Brasilia
Type: Case Reports | Journal: Revista da Sociedade Brasileira de Medicina Tropical | Year: 2016
The human T-cell lymphotropic virus-1 (HTLV-1) affects worldwide population; the estimated number of currently infected individuals is 10-20 million. In this report, we describe the clinical findings of three family members with vertical transmission of HTLV-1. This case report highlights the importance of healthcare providers who have optimal knowledge about HTLV-1 including its transmission and pertinent attributes, and who are able to provide affected individuals with adequate information regarding their condition.