Alor Setar, Malaysia
Alor Setar, Malaysia

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PubMed | Biostatistics unit, Hospital Sultanah Nur Zahirah HSNZ, Hospital Ampang, Hospital Sultanah Bahiyah HSB and 2 more.
Type: Journal Article | Journal: Malaysian orthopaedic journal | Year: 2014

Hip fractures entail a growing economic burden on the health care system. Study is warranted to further our understanding of its patterns and to create increased awareness in health care providers and the public.Data was extracted from the ongoing National Orthopaedic Registry of Malaysia (NORM), for the period June 2008 till December 2009. Patients aged 50 years and above without previous pathological fracture hip fractures were included in the study.Most hip fracture patients were 70 years and above (69.5%) with a mean (SD) age of 73.8 (10.3) years. Females represented the majority of the patients in this study (68.4%). Low energy trauma (i.e. trivial fall) was to the main mechanism of hip fractures in this study (81.3%).Aging adults should be made aware of timely preventive strategies (including osteoporosis prevention) fall prevention measures, and encouraged to maintain physically active lifestyles.Hip fracture, pre-fracture status.

Ang H.L.,Hospital Tengku Ampuan Rahimah HTAR | Mohamad Adam B.,Biostatistics Unit | Tajuddin A.,Hospital Sultanah Nur Zahirah HSNZ | Isnoni I.,Hospital Sultanah Nur Zahirah HSNZ | And 6 more authors.
Malaysian Journal of Public Health Medicine | Year: 2016

The incidence of hip fractures is increasing within the aging population.We determined the risk factors of in-hospital mortality following hip fracture across major hospitals in Malaysia. This is a retrospective cohort review from 18 hospitals across Malaysia in National Orthopaedic Registry of Malaysia (NORM) . We collected demographic data, pre-fracture co-morbidities, previous hip fracture, pre-fracture walking ability, fracture type and stability, mechanism of injury, type of management (operative or non-operative), operation types and grade of surgeon. Between 2008 and 2009, 685 patients were admitted with a hip fracture to 18 government hospitals with orthopaedic service. The overall in-hospital mortality was 2.2%. We found more in-hospital mortality in elderly patients and patients with eye and hearing problems as pre-fracture morbidity. In conclusion, patients who were elderly with multiple co-morbidities especially those with eye and hearing impairment were had higher risk for immediate mortality.

Marican Abu Backer F.,Universiti Sains Malaysia | Nik Mustapha N.R.,Hospital Sultanah Bahiyah HSB | Othman N.H.,Universiti Sains Malaysia
Infectious Diseases in Obstetrics and Gynecology | Year: 2011

Objective. We studied the clinicopathological parameters of adenocarcinoma arising from endocervix (ECA) and from endometrium (EMA) based on the expression of P16ink4a, P21waf1, and p27Kip1 proteins. Study Design. Immunohistochemistry was done on sections of confirmed ECA and EMA from hysterectomy specimens which have had no prior chemotherapy/radiotherapy. Results. There were 40 ECAs and 92 EMAs. The mean age of ECA was 49.82 (SD 10.29); the youngest was 30 years old and the oldest 75 years old. The mean age of EMA was 54.45 (SD 10.92); the youngest was 30 years old and the oldest was 82 years old. For ECA, the size of the tumour is significantly associated with age and with depth of infiltration. FIGO stage is associated with histological grade. p21WAF1 expression is significantly associated with infiltration of the corpus and lymph node metastasis. p27Kip1 expression is significantly associated with lymph node invasion. The presence of lymph node metastasis is strongly associated when p16INK4a and p27Kip1 expressions are analyzed in combination. For EMA, p16INK4a expression is associated with histologic grade. Conclusion. Our study shows that we could use these cell cycle markers as predictors for more aggressive subsets of adenocarcinoma of the cervix and endometrium. © 2011 Farveen Marican Abu Backer et al.

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