Ross J.G.C.,University of Washington |
Bernaudin F.,Hospital Intercommunal de Creteil |
Strunk R.C.,University of Washington |
Kamdem A.,Hospital Intercommunal de Creteil |
And 4 more authors.
Journal of Pediatric Hematology/Oncology | Year: 2011
Asthma in children with sickle cell anemia (SCA) is associated with increased morbidity and mortality. However, the definition of asthma in SCA is based on a physician's impression. In a retrospective cohort of children with SCA, relationships between a physician diagnosis of asthma and total and allergen-specific immunoglobulin E levels were evaluated. In children with SCA, elevated total and specific immunoglobulin E levels were significantly associated with a diagnosis of asthma (P<0.05), further supporting the concept that asthma is a separate comorbid condition of SCA. Copyright © 2011 by Lippincott Williams & Wilkins. Source