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Lisbon, Portugal

Macias V.C.,Hospital de Curry Cabral | Rafael M.,Instituto Portugues Of Oncologia Francisco Gentil | Fernandes C.,Instituto Portugues Of Oncologia Francisco Gentil | Rosa J.C.,Instituto Portugues Of Oncologia Francisco Gentil
Anais Brasileiros de Dermatologia | Year: 2013

Although infrequent, alopecia can be caused by benign cutaneous tumours. Neurofibromas are common benign tumors that originate in the peripheral nerve sheath. Diffuse neurofibroma is a rare variant of neu-rofibroma that is thought to occur mainly in the head and neck of children and young adults. Histology generally shows an infiltrative tumor, composed of spindle cells in the dermis and subcutaneous tissue. Despite being rare, malignant transformation has been reported. The association between diffuse neurofibromas and neurofi-bromatosis type 1 still remains to be determined since some authors question the low incidence usually described. We report the case of a 42-year-old man who had a diffuse neurofibroma on the scalp presenting as alopecic plaques. © 2013 by Anais Brasileiros de Dermatologia.

Mendes J.J.,Centro Hospitalar Of Lisbon Central Epe | Marques-Costa A.,Podiatry Outpatient Clinic | Vilela C.,University of Lisbon | Neves J.,Centro Hospitalar Of Lisbon Central Epe | And 3 more authors.
Diabetes Research and Clinical Practice | Year: 2012

Aims: An epidemiological survey of diabetic foot infections (DFIs) in Lisbon, stratifying the bacterial profile based on patient demographical data, diabetic foot characteristics (PEDIS classification), ulcer duration and antibiotic therapy. Methods: A transversal observational multicenter study, with clinical data collection using a structured questionnaire and microbiological products (aspirates, biopsies or swabs collected using the Levine method) of clinically infected foot ulcers of patients with diabetes mellitus (DM). Results: Forty-nine hospitalized and ambulatory patients were enrolled in this study, and 147 microbial isolates were cultured. Staphylococcus was the main genus identified, and methicillin-resistant Staphylococcus aureus (MRSA) was present in 24.5% of total cases. In the clinical samples collected from patients undergoing antibiotic therapy, 93% of the antibiotic regimens were considered inadequate based on the antibiotic susceptibility test results. The average duration of an ulcer with any isolated multi-drug resistant (MDR) organism was 29 days, and previous treatment with fluoroquinolones was statistically associated with multi-drug resistance. Conclusions: Staphylococcus aureus was the most common cause of DFIs in our area. Prevalence and precocity of MDR organisms, namely MRSA, were high and were probably related to previous indiscriminate antibiotic use. Clinicians should avoid fluoroquinolones and more frequently consider the use of empirical anti-MRSA therapy. © 2011 Elsevier Ireland Ltd.

Fidalgo C.,Instituto Portugues Of Oncologia Of Lisbon Francisco Gentil | Fidalgo C.,Instituto Portugues Of Oncologia Francisco Gentil | Calado J.,Hospital de Curry Cabral | Cravo M.,Instituto Portugues Of Oncologia Of Lisbon Francisco Gentil
BioDrugs | Year: 2010

Systemic AA amyloidosis is a serious complication of many chronic inflammatory disorders. Its association with Crohn's disease implies that the inflammatory burden is high enough for amyloid fibrils to form deposits in tissues. A case is presented in which this complication occurred while the patient was clinically well, with biological and endoscopic markers showing an inactive or mildly active disease under anti-tumor necrosis factor alpha therapy. © 2010 Adis Data Information BV. All rights reserved.

Maio P.,Hospital de Curry Cabral | Santos R.,Hospital de Curry Cabral | Cardoso J.,Hospital de Curry Cabral
Dermatology Online Journal | Year: 2012

The importance of emotional factors in dermatological disorders has been recognized for several decades. However, very few reports have been published to date about the diagnosis and management of these disorders. A 78-year-old woman came to our department with 3 months evolution of a symmetrically distributed dermatosis involving only the face. It was characterized by multiple erosions, some of which had slightly geometrical shapes. We report an unusual case of late onset dermatitis artefacta with a rare successful outcome. © 2012 Dermatology Online Journal.

Pinto R.,Dr Gama Pinto Institute of Ophthalmology | Lino S.,Hospital de Curry Cabral | Nogueira V.,Dr Gama Pinto Institute of Ophthalmology | Fonseca A.,Hospital de Santa Maria | Ornelas C.,Dr Gama Pinto Institute of Ophthalmology
International Journal of STD and AIDS | Year: 2013

We present a case of structural and functional changes compatible with didanosine retinopathy in a patient who also developed non-cirrhotic portal hypertension.

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