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A pharmaceutical composition comprised of uric acid and citicoline is for the neuroprotective treatment of patients with ictus.


Fernandez H.,Galgo Medical | Macho J.M.,Hospital Clinic Provincial de Barcelona | Blasco J.,Hospital Clinic Provincial de Barcelona | Roman L.S.,Hospital Clinic Provincial de Barcelona | And 3 more authors.
International Journal of Computer Assisted Radiology and Surgery | Year: 2015

Purpose: An important issue in the deployment of braided stents, such as flow diverters, is the change in length, also known as foreshortening, underwent by the device when is released from the catheter into a blood vessel. The position of the distal end is controlled by the interventionist, but knowing a priori the position of the proximal end of the device is not trivial. In this work, we assess and validate a novel computer method to predict the length that a braided stent will adopt inside a silicon model of an anatomically accurate vessel. Methods: Three-dimensional rotational angiography images of aneurysmatic patients were used to generate surface models of the vessels (3D meshes) and then create accurate silicon models from them. A braided stent was deployed into each silicon model to measure its length. The same stents deployed on the silicon models were virtually deployed on the 3D meshes using the method being evaluated. Results: The method was applied to five stent placements on three different silicon models. The length adopted by the real braided device in the silicon models varies between 15 and 30 % from the stent length specified by the manufacturer. The final length predicted by the method was within the estimated error of the measured real stent length. Conclusions: The method provides, in a few seconds, the length of a braided stent deployed inside a vessel, showing an accurate estimation of the final length for the cases studied. This technique could provide useful information for planning the intervention and improve endovascular treatment of intracranial aneurysms in the future. © 2015, CARS. Source

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