Horphag Research

Genève, Switzerland

Horphag Research

Genève, Switzerland
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News Article | May 12, 2017
Site: www.prnewswire.com

Attendees of the event, who enjoyed a full round of golf, reception, and dinner, also supported the nonprofit by raising more than $26,000 on site. The success of the event was made possible through the generous support of the following sponsors: The Vitamin Shoppe®, Nature's Value, Inc., Barrington Nutritionals, Glanbia Performance Nutrition, H&M USA, Inc.,  Nutrawise Health and Beauty, Vitaquest, Iovate Health Sciences, Naturex, Inc., ABH Pharma, Inc., CapsCanada Corp., Kura Nutrition, NutraClick, Package All Corp., Reservage & Twinlab, Dymatize, Healthy Natural Solutions, Horphag Research (USA), Inc., Indena USA, Inc., Natural Factors, Nutrabolt, Nutraland USA, Inc., and ZoomEssence. Individuals interested in attending a future Vitamin Angels event can visit: vitaminangels.org/attend-an-event. Throughout the month of May, online and in stores, the Vitamin Shoppe is accepting customer donations to support Vitamin Angels. About The Vitamin Shoppe The Vitamin Shoppe® is an omni-channel, specialty retailer and contract manufacturer of nutritional products based in Secaucus, New Jersey.  In its stores and on its website, the Company carries a comprehensive retail assortment including: vitamins, minerals, specialty supplements, herbs, sports nutrition, homeopathic remedies, green living products, and beauty aids.  In addition to offering products from approximately 900 national brands, the Vitamin Shoppe also carries products under The Vitamin Shoppe®, BodyTech®, True Athlete®, MyTrition®, plnt®, ProBioCare®, Next Step® and Betancourt Nutrition® brands. The Vitamin Shoppe conducts business through more than 775 company-operated retail stores under The Vitamin Shoppe and Super Supplements retail banners, and through its website, www.vitaminshoppe.com.  Follow The Vitamin Shoppe® on Facebook at http://www.facebook.com/THEVITAMINSHOPPE and on Twitter at http://twitter.com/VitaminShoppe. About Nature's Value Nature's Value is one of the world's premier nutritional supplement manufacturers. For over 20 years Nature's Value has been producing only the finest quality nutritional supplements. Nature's Value is part of the industry that promotes good health and well-being in individuals' lives. Its goal is to provide seamless, fully integrated manufacturing services at quality and price levels that meet or exceed our client's needs and expectations. Vitamin Angels helps at-risk populations in need—specifically pregnant women, new mothers, and children under five—gain access to lifesaving and life changing vitamins and minerals. Vitamin Angels works to reach underserved communities across the U.S. and in nearly 60 countries around the world. Vitamin Angels has a four-star rating from Charity Navigator for Financial Health, Accountability and Transparency. To learn more, visit vitaminangels.org. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/benefit-golf-outing-raises-330000-for-vitamin-angels-300456606.html


Gulati O.P.,Horphag Research
Phytotherapy Research | Year: 2015

The present review provides an update of the biological actions of Pycnogenol® in the treatment of metabolic syndrome and related disorders such as obesity, dyslipidaemia, diabetes and hypertension. Pycnogenol® is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. Subsp. atlantica. Its strong antioxidant, antiinflammatory, endothelium-dependent vasodilator activity, and also its anti-thrombotic effects make it appropriate for targeting the multifaceted pathophysiology of metabolic syndrome. Clinical studies have shown that it can reduce blood glucose levels in people with diabetes, blood pressure in mild to moderate hypertensive patients, and waist circumference, and improve lipid profile, renal and endothelial functions in metabolic syndrome. This review highlights the pathophysiology of metabolic syndrome and related clinical research findings on the safety and efficacy of Pycnogenol®. The results of clinical research studies performed with Pycnogenol® are discussed using an evidence-based, target-oriented approach following the pathophysiology of individual components as well as in metabolic syndrome overall. Copyright © 2015 John Wiley & Sons, Ltd.


Gulati O.P.,Horphag Research
Phytotherapy Research | Year: 2014

The present review provides an update of the biological profile of Pycnogenol in the light of its use in the treatment of chronic venous insufficiency (CVI) and related venous disorders such as deep vein thrombosis (DVT), post-thrombotic syndrome, long haul air-travel-related leg oedema, venous ulcers and acute haemorrhoids. Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. subsp. atlantica. Its strong antioxidant, anti-inflammatory and vasodilator activities, antithrombotic effects and collagen stabilizing properties make it uniquely able to target the multi facet pathophysiology of CVI and related venous disorders. Clinical studies have shown that it can reduce oedema of the legs in CVI, reduce the incidence of deep venous thrombosis during long haul flights and enhance the healing of venous ulcers and haemorrhoidal episodes by topical application and/or oral administration. This review highlights clinical research findings on the safety, compliance and efficacy of Pycnogenol, including its use in combination products. © 2013 John Wiley & Sons, Ltd.


Marini A.,IUF Leibniz Research Institute for Environmental Medicine | Grether-Beck S.,IUF Leibniz Research Institute for Environmental Medicine | Jaenicke T.,IUF Leibniz Research Institute for Environmental Medicine | Weber M.,IUF Leibniz Research Institute for Environmental Medicine | And 5 more authors.
Skin Pharmacology and Physiology | Year: 2012

Introduction and Objectives: In recent years there has been an increasing interest in the use of nutritional supplements to benefit human skin. Molecular evidence substantiating such effects, however, is scarce. In the present study we investigated whether nutritional supplementation of women with the standardized pine bark extract Pycnogenol®will improve their cosmetic appearance and relate these effects to expression of corresponding molecular markers of their skin. Materials and Methods: For this purpose 20 healthy postmenopausal women were supplemented with Pycnogenol for 12 weeks. Before, during and after supplementation, their skin condition was assessed (i) by employing noninvasive, biophysical methods including corneometry, cutometry, visioscan and ultrasound analyses and (ii) by taking biopsies and subsequent PCR for gene expression analyses related to extracellular matrix homeostasis. Results: Pycnogenol supplementation was well tolerated in all volunteers. Pycnogenol significantly improved hydration and elasticity of skin. These effects were most pronounced in women pre-senting with dry skin conditions prior to the start of supplementation. The skin-physiological improvement was accompanied by a significant increase in the mRNA expression of hyaluronic acid synthase-1 (HAS-1), an enzyme critically involved in the synthesis of hyaluronic acid, and a noticeable increase in gene expression involved in collagen de novo synthesis. Conclusions: This study provides skin-physiological and for the first time molecular evidence that Pycnogenol supplementation benefits human skin by increasing skin hydration and skin elasticity. These effects are most likely due to an increased synthesis of extracellular matrix molecules such as hyaluronic acid and possibly collagen. Pycnogenol supplementation may thus be useful to counteract the clinical signs of skin aging. Copyright © 2012 S. Karger AG, Basel.


Orszaghova Z.,Comenius University | Waczulikova I.,Comenius University | Burki C.,Horphag Research | Rohdewald P.,University of Munster | urackova Z.,Comenius University
Phytotherapy Research | Year: 2015

The purpose of our study was to examine the psychological benefits of the treatment with Robuvit® (Horphag Research Ltd.) - polyphenolic extract obtained from the wood of oak Quercus robur - on the healthy elderly individuals using energy subscale scores of the Activation - Deactivation Adjective Check List. Analysis was focused on the comparison of pre-post treatment effect of Robuvit on symptoms of fatigue. In the total group of volunteers, significant increase of average question scores was found in three of four subscales of feelings (energy, tiredness, and tension) after 4 weeks of Robuvit administration. Effects of extract were observed mainly after stratification of total group of volunteers according to the level of feeling at the pre-treatment questionnaire. Our results demonstrate positive effect of Robuvit on mental and energy level in healthy human without any unwanted side effects. © 2015 The Authors Phytotherapy Research Published by John Wiley & Sons Ltd.


PubMed | Horphag Research
Type: Journal Article | Journal: Phytotherapy research : PTR | Year: 2014

The present review provides an update of the biological profile of Pycnogenol in the light of its use in the treatment of chronic venous insufficiency (CVI) and related venous disorders such as deep vein thrombosis (DVT), post-thrombotic syndrome, long haul air-travel-related leg oedema, venous ulcers and acute haemorrhoids. Pycnogenol is a French maritime pine bark extract produced from the outer bark of Pinus pinaster Ait. subsp. atlantica. Its strong antioxidant, anti-inflammatory and vasodilator activities, antithrombotic effects and collagen stabilizing properties make it uniquely able to target the multi facet pathophysiology of CVI and related venous disorders. Clinical studies have shown that it can reduce oedema of the legs in CVI, reduce the incidence of deep venous thrombosis during long haul flights and enhance the healing of venous ulcers and haemorrhoidal episodes by topical application and/or oral administration. This review highlights clinical research findings on the safety, compliance and efficacy of Pycnogenol, including its use in combination products.

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