HORIBA Medical

Murviel-lès-Montpellier, France

HORIBA Medical

Murviel-lès-Montpellier, France
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NEW YORK--(BUSINESS WIRE)--Medpod, Inc. a digital health innovator, is officially launching the Medpod platform, which integrates proprietary communication software with real-time active polling of medical and laboratory device data to extend the physician’s reach, transform traditional care environments and create new beneficial settings of care.. Medpod will be showcasing the medical office of the future at the upcoming ATA conference in Orlando, FL. The telemedicine innovator joins ATA as a platinum sponsor and participant in the Experience Zone where simulations will allow visitors to experience telemedicine first-hand. Medpod is developing next-generation general care, on-demand care and distance care. Medpod is meeting the difficult challenges of healthcare head-on through the development, aggregation and integration of medical software, hardware and physical infrastructure into seamless, innovative care delivery solutions. By leveraging technologies that empower healthcare providers to extend their reach, Medpod optimizes available resources and deliver the value of augmented medicine. Medpod works with best-in-class medical device manufacturers, distributors, physicians and health systems, to engineer and innovate new physical structures and delivery care options. Partners include such prestigious leaders as: Henry Schein, Inc., Midmark Corporate, Welch Allyn, Hill-Rom, HORIBA Medical, WellnessCodes, BewellConnect Corp, and MasterWorld. The company’s technology enables any practice, ambulatory clinic, hospital system or healthcare organization to augment the medical care it delivers and empowers practitioners to improve patient lives and revolutionize the standard of healthcare. In the Experience Zone Simulation Showcase, participants will walk through a guided tour of four distinct areas to learn how telemedicine services are best utilized in environments where they are often provided. The medical office of the future will join three other simulations: interoperability of technology in the ICU, the ER, and the Senior Living facility. Tours will last 15 minutes and take place regularly throughout the show. Reservations are required for the tour and can be made through the ATA. The ATA 2017 International Conference & Tradeshow is the world’s premiere event in the telehealth industry that brings together professionals to share their expertise and knowledge with their peers. The conference provides an invaluable education experience and an opportunity to attend over 100 sessions that highlight the hottest topics in the telemedicine industry. For more information on the Medpod exhibit, contact: Lisa Osorio, Senior Director, Integrated Marketing, Lisa.Osorio@henryschein.com 631.390.8287. ABOUT MEDPOD: Medpod, Inc. has created a proprietary healthcare platform that combines cutting edge infrastructure and software with professional medical and laboratory devices to extend the physician’s reach, transform traditional care environments and create new beneficial settings of patient care. Medpod works in close collaboration with best-in-class medical device manufacturers, distributors, physicians and health systems, to engineer and innovate new physical structures and delivery care options. Medpod’s mission is to enable healthcare providers to extend reach, redistribute resources, build volume and transform their business by advancing the science of virtual care, reducing costs and improving outcomes and enabling the new value based healthcare paradigm. Medpod… more than telemedicine, augmented medicine.


Rongeat N.,Horiba Medical | Ledroit S.,Horiba Medical | Chauvet L.,Horiba Medical | Cremien D.,Horiba Medical | And 3 more authors.
Journal of Biomedical Optics | Year: 2011

Precise identification of eosinophils, basophils, and specific subpopulations of blood cells (B lymphocytes) in an unconventional automatic hematology analyzer is demonstrated. Our specific apparatus mixes two excitation radiations by means of an acousto-optics tunable filter to properly control fluorescence emission of phycoerythrin cyanin 5 (PC5) conjugated to antibodies (anti-CD20 or anti-CRTH2) and Thiazole Orange. This way our analyzer combining techniques of hematology analysis and flow cytometry based on multiple fluorescence detection, drastically improves the signal to noise ratio and decreases the spectral overlaps impact coming from multiple fluorescence emissions. © 2011 Society of Photo-Optical Instrumentation Engineers (SPIE).


Rongeat N.,HORIBA Medical | Leproux P.,University of Limoges | Couderc V.,University of Limoges | Brunel P.,HORIBA Medical | And 5 more authors.
Cytometry Part A | Year: 2012

Multiple wavelength operation in a flow cytometer is an exciting way for cell analysis based on both fluorescence and optical scattering processing. For example, this multiparametric technique is currently used to differentiate blood cells subpopulations. The choice of excitation wavelengths matching fluorochrome spectra (it is currently the opposite) and the use of a broader range of fluorochromes can be made by taking advantage of a filtered supercontinuum white light source. In this study, we first wished to validate the use of a specific triggered supercontinuum laser in a flow cytometer based on white light scattering and electric sizing on human blood cells. Subsequently, to show the various advantages of this attractive system, using scattering effect, electrical detections, and fluorescence analysis, we realized cells sorting based on DNA/RNA stained by thiazole orange. Discrimination of white blood cells is efficiently demonstrated by using a triggered supercontinuum-based flow cytometer operating in a "one cell-one shot" configuration. The discriminated leukocyte populations are monocytes, lymphocytes, granulocytes, immature granulocytes, and cells having a high RNA content (monoblasts, lymphoblasts, and plasma cells). To the best of our knowledge, these results constitute the first practical demonstration of flow cytometry based on triggered supercontinuum illumination. This study is the starting point of a series of new experiments fully exploiting the spectral features of such a laser source. For example, the large flexibility in the choice of the excitation wavelength allows to use a larger number of fluorochromes and to excite them more efficiently. Moreover, this work opens up new research directions in the biophotonics field, such as the combination of coherent Raman spectroscopy and flow cytometry techniques. © 2012 International Society for Advancement of Cytometry.


— The analysts forecast the global tissue diagnostics market to grow at a CAGR of 11.59% during the period 2016-2020. Tissue diagnostics involves the diagnosis of diseases or analysis of the biological causes of the disease by extracting and analyzing a specific tissue. It has a broad range of applications in clinical research, clinical diagnostics, and cell biology. It is considered one of the most accurate techniques for the diagnosis of inflammatory conditions. Medical specialists particularly use tissue diagnostics in the area of molecular biology for cancer screening, therapy selection, diagnosis, and relapse monitoring. It helps in the screening and diagnosis of lymphoma, melanoma, leukemia, and breast, ovarian, cervical, head and neck, pancreatic, non-small cell lung, colorectal, brain, prostate, lung, and endometrial cancers. Pathologists use different technologies such as in situ hybridization (ISH), immunohistochemistry (IHC), special staining, and digital pathology and related methods including core biopsy, fine needle aspiration cytology, and open biopsy to study and diagnose cells. For more information or any query mail at sales@wiseguyreports.com The report covers the present scenario and the growth prospects of the global tissue diagnostics market for 2016-2020. To calculate the market size, the report considers the revenue generated from the sales of diagnostic devices based on the following techniques: The market is divided int the following segments based on geography: • Americas • APAC • EMEA The report, Global Tissue Diagnostics Market 2016-2020, has been prepared based on an in-depth market analysis with inputs from industry experts. The report covers the market landscape and its growth prospects over the coming years. The report also includes a discussion of the key vendors operating in this market. Other prominent vendors • 20/20 GeneSystems • Abcam • AdnaGen • Advanced Cell Diagnostics • Affymetrix • Agendia • AutoGenomics • AVIVA BioSciences • Biocare Medical • Biocartis • Cancer Genetics • ELITechGroup • Enzo Biochem • Epic Sciences • Fluidigm • HORIBA Medical • Janssen Diagnostics • Olympus Diagnostics Systems Group • Omnyx (a joint venture of GE Healthcare and the University of Pittsburgh Medical Center, US) • Oxford Gene Technology • PANAGENE • Protea Biosciences Group • Sakura Finetek Market driver • Implementation by new customers • For a full, detailed list, view our report Market challenge • Insurance coverage and reimbursement issues • For a full, detailed list, view our report Key questions answered in this report • What will the market size be in 2020 and what will the growth rate be? • What are the key market trends? • What is driving this market? • What are the challenges to market growth? • Who are the key vendors in this market space? • What are the market opportunities and threats faced by the key vendors? • What are the strengths and weaknesses of the key vendors? PART 06: Reimbursement and coverage: An overview • Current scenario: Validating diagnostic tests • Reimbursement structure in US • Reimbursement structure in EU • Prevailing issues of reimbursement policies PART 08: Market segmentation by technology • Global tissue diagnostics market by advanced staining • Global tissue diagnostics market by digital pathology • Global tissue diagnostics market by preanalytical and routine staining PART 09: Market segmentation by product • Global tissue diagnostics market segmentation by consumables • Global tissue diagnostics market segmentation by instruments For more information or any query mail at sales@wiseguyreports.com ABOUT US: Wise Guy Reports is part of the Wise Guy Consultants Pvt. Ltd. and offers premium progressive statistical surveying, market research reports, analysis & forecast data for industries and governments around the globe. Wise Guy Reports features an exhaustive list of market research reports from hundreds of publishers worldwide. We boast a database spanning virtually every market category and an even more comprehensive collection of market research reports under these categories and sub-categories. For more information, please visit https://www.wiseguyreports.com


Manaargadoo-Catin M.,Horiba Medical | Manaargadoo-Catin M.,Montpellier University | Ali-Cherif A.,Horiba Medical | Pougnas J.-L.,Horiba Medical | Perrin C.,Montpellier University
Advances in Colloid and Interface Science | Year: 2016

An overview of the use of surfactants for erythrocyte lysis and their cell membrane action mechanisms is given. Erythrocyte membrane characteristics and its association with the cell cytoskeleton are presented in order to complete understanding of the erythrocyte membrane distortion. Cell homeostasis disturbances caused by surfactants might induce changes starting from shape modification to cell lysis. Two main mechanisms are hypothesized in literature which are osmotic lysis and lysis by solubilization even if the boundary between them is not clearly defined. Another specific mechanism based on the formation of membrane pores is suggested in the particular case of saponins. The lytic potency of a surfactant is related to its affinity for the membrane and the modification of the lipid membrane curvature. This is to be related to the surfactant shape defined by its hydrophobic and hydrophilic moieties but also by experimental conditions. As a consequence, prediction of the hemolytic potency of a given surfactant is challenging. Several studies are focused on the relation between surfactant erythrolytic potency and their physico-chemical parameters such as the critical micellar concentration (CMC), the hydrophile-lipophile balance (HLB), the surfactant membrane/water partition coefficient (K) or the packing parameter (P). The CMC is one of the most important factors considered even if a lytic activity cut-off effect points out that the only consideration of CMC not enough predictive. The relation K.CMC must be considered in addition to the CMC to predict the surfactant lytic capacity within the same family of non ionic surfactant. Those surfactant structure/lytic activity studies demonstrate the requirement to take into account a combination of physico-chemical parameters to understand and foresee surfactant lytic potency. © 2015 Elsevier B.V. All rights reserved.


Rongeat N.,HORIBA Medical | Brunel P.,HORIBA Medical | Gineys J.-P.,HORIBA Medical | Cremien D.,HORIBA Medical | And 2 more authors.
Optics Express | Year: 2011

The aim of this study is to combine multiple excitation wavelengths in order to improve accuracy of fluorescence characterization of labeled cells. The experimental demonstration is realized with a hematology analyzer based on flow cytometry and a CW laser source emitting two visible wavelengths. A given optical encoding associated to each wavelength allows fluorescence identification coming from specific fluorochromes and avoiding the use of noisy compensation method. © 2011 Optical Society of America.


Isebe D.,HORIBA Medical | Nerin P.,HORIBA Medical
International Journal for Numerical Methods in Biomedical Engineering | Year: 2013

This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice-electrode system. The model allows to simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and to compute the voltage pulses generated by the modification of the inner dielectric medium. This approach gives important information about particles size distribution and allows to quantify the role of trajectory and orientation of particles on the size measurement. Copyright © 2012 John Wiley & Sons, Ltd. In most cases, counting and sizing of biological cells are based on electrical gating through a microorifice in a close orifice-electrode system that we don't experimentally apprehend. In this framework, we have developed a complete numerical approach to compute the exact particle size distribution by taking into account the trajectory and the orientation of the particles through the microorifice. This numerical approach is fully innovative in diagnosis engineering and can be used to perform particle sizing measurement by optimizing shape design or fluidic conditions. © 2012 John Wiley & Sons, Ltd.


PubMed | HORIBA Medical
Type: Journal Article | Journal: International journal for numerical methods in biomedical engineering | Year: 2013

This paper describes how to numerically tackle the problem of counting and sizing particles by impedance measurement in an orifice-electrode system. The model allows to simulate the particle dynamics submitted to strong hydrodynamic stresses through a microorifice and to compute the voltage pulses generated by the modification of the inner dielectric medium. This approach gives important information about particles size distribution and allows to quantify the role of trajectory and orientation of particles on the size measurement.


PubMed | Horiba Medical and Montpellier University
Type: | Journal: Advances in colloid and interface science | Year: 2016

An overview of the use of surfactants for erythrocyte lysis and their cell membrane action mechanisms is given. Erythrocyte membrane characteristics and its association with the cell cytoskeleton are presented in order to complete understanding of the erythrocyte membrane distortion. Cell homeostasis disturbances caused by surfactants might induce changes starting from shape modification to cell lysis. Two main mechanisms are hypothesized in literature which are osmotic lysis and lysis by solubilization even if the boundary between them is not clearly defined. Another specific mechanism based on the formation of membrane pores is suggested in the particular case of saponins. The lytic potency of a surfactant is related to its affinity for the membrane and the modification of the lipid membrane curvature. This is to be related to the surfactant shape defined by its hydrophobic and hydrophilic moieties but also by experimental conditions. As a consequence, prediction of the hemolytic potency of a given surfactant is challenging. Several studies are focused on the relation between surfactant erythrolytic potency and their physico-chemical parameters such as the critical micellar concentration (CMC), the hydrophile-lipophile balance (HLB), the surfactant membrane/water partition coefficient (K) or the packing parameter (P). The CMC is one of the most important factors considered even if a lytic activity cut-off effect points out that the only consideration of CMC not enough predictive. The relation K.CMC must be considered in addition to the CMC to predict the surfactant lytic capacity within the same family of non ionic surfactant. Those surfactant structure/lytic activity studies demonstrate the requirement to take into account a combination of physico-chemical parameters to understand and foresee surfactant lytic potency.


PubMed | HORIBA Medical, Chiyoda Corporation, Osaka Medical College and HORIBA ABX
Type: Journal Article | Journal: International journal of laboratory hematology | Year: 2015

We evaluated the basic performance of Microsemi CRP, an unique automated hematology analyzer which can simultaneously measure CBC including 3-part WBC differential (3-Diff) and CRP using whole blood treated with EDTA-2K anticoagulant.We found that it produced generally the acceptable results for all parameters performed (repeatability, reproducibility, linearity, interference effect, carry over, and correlation) using control materials, fresh human whole bloods, and serum samples.CBC data examined using Microsemi CRP showed the good correlation with the previous model, Micros CRP200 (r 0.9), and also those obtained using the routine analyzer, ADVIA 2120i (r 0.989). Concerning the 3-Diff, both GRA (%) and LYM (%) showed the excellent correlation coefficient between Microsemi CRP and Micros CRP200 (r 0.992) as well as ADVIA 2120i (r 0.957). MON (%) showed good correlation between Microsemi CRP and Micros CRP200 (r = 0.959), but lower correlation between Microsemi CRP and ADVIA 2120 i (r = 0.471). CRP data showed the good correlation with HITACHI7600 (r 0.997) and Micros CRP200 (r 0.997).From these findings, we concluded that Microsemi CRP seemed the convenient laboratory analyzer in the setting of point of care testing (POCT) especially at NICU or primary care unit.

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