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Murviel-lès-Montpellier, France

Delpech P.,French National Institute for Agricultural Research | Bornes S.,University dAuvergne | Alaterre E.,French National Institute for Agricultural Research | Alaterre E.,HORIBA ABX SAS | And 4 more authors.
Food Microbiology | Year: 2015

Growth of the foodborne pathogen Staphylococcus aureus can be inhibited in milk and in cheese by the hydrogen peroxide-producing Lactococcus garvieae N201 dairy strain. Transcriptomic responses of two S.aureus strains, the S. aureus SA15 dairy strain and the MW2 human pathogenic strain, to this growth inhibition were investigated in Brain-Heart Infusion broth under a high or a low aeration level. We demonstrated that S.aureus MW2 had a higher resistance to L.garvieae inhibition under the high aeration level: this correlated to a higher survival under hydrogen peroxide exposure. Conversely, the two strains were similarly inhibited under the low aeration level. Expression of S.aureus genes involved in response to H2O2 or other stresses as well as in cell division was generally repressed by L.garvieae. However, differential expressions between the two S.aureus strains were observed, especially under the high aeration level. Additionally, expression of virulence-related genes (enterotoxins, regulatory genes) was modulated by L.garvieae depending on the aeration level and on the S.aureus strain. This study led to new insights into potential molecular mechanisms of S.aureus inhibition by Lactic Acid Bacteria via H2O2 production. © 2015 Elsevier Ltd. Source

Horiba Abx Sas | Date: 2013-03-14

The subject of the invention is a device for positioning an object in space, comprising at least 4 plates, each one able to move with respect to another of said plates which is contiguous with it along one of the 3 axes of space, it being possible for the movement of one plate with respect to another plate to be guided by a tenon/mortise assembly in which said tenon is secured to one of the plates and its mortise is produced in the other plate, the spatial orientation of each of the tenon/mortise assemblies being different from the other 2 and along one of the 3 axes of space.

The present invention concerns a device for analyzing biological parameters from a sample (

The invention relates to an electro-optical device for measurements of flow for the characterization of microparticles, comprising a measurement chamber (CUM) in which there circulates the flow of the fluid to be characterized, at least two luminous sources (S

The present invention relates to a method for compensating for the breakdown of a reagent stored in an aqueous phase comprising at least one fluorescent compound and enabling the identification of particles, including the steps of: (i) measuring the fluorescence level FLUOm(t) of particles marked with said reagent; (ii) measuring the absorbance at at least one wavelength of a solution of said reagent, at a time t close to the time of said fluorescence level FLUOm(t) measurements, so as to determine at least one current optical density DO(t) of the reagent; and (iii) calculating a correction of the fluorescent level measurements using said at least one current optical density DO(t) and at least one initial optical density DO(0) of the reagent that has not been broken down. The invention also relates to a biological analysis device implementing the method.

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