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Mountain Road, VA, United States

Hollins University is a four-year private institution of higher education located on a 475-acre campus on the border of Roanoke and Botetourt counties in the U.S. state of Virginia. Founded in 1842 as Valley Union Seminary in the historical settlement of Botetourt Springs, it is one of the oldest institutions of higher education for women in the United States.Hollins has since evolved into a full university with approximately 800 enrolled undergraduate and graduate students. As Virginia's first chartered women's college, all undergraduate programs are female-only. Men are admitted to the graduate-level programs.Hollins is known for its undergraduate and graduate writing programs, which have produced Pulitzer Prize–winning authors Annie Dillard, current U.S. poet laureate Natasha Trethewey, and Henry S. Taylor. Other prominent alumnae include pioneering sportswriter Mary Garber, 2006 Man Booker Prize winner Kiran Desai, Goodnight Moon author Margaret Wise Brown, Lee Smith, photographer Sally Mann, and Ellen Malcolm, founder of EMILY's List. Wikipedia.

Han J.,Hollins University | Han J.,University of Virginia
Physical Review A - Atomic, Molecular, and Optical Physics | Year: 2011

We have observed a density-dependent frequency shift of more than 4 MHz in a cold 85Rb Rydberg gas trapped in a magneto-optical trap. A one-dimensional linearly aligned four-body model is proposed to explain the experimental data, and the calculation matches the experimental data. The calculation also shows that if the energy detuning between the two coupled states, the nsnsns(n+1)s and nsnsnpnp states in this case, is small, the lowest level of the nsnsnpnp manifold has the maximum mixing probability, causing a frequency shift instead of line broadening. The results reported may be used for few-body blockade, Rydberg single-atom imaging, studying few-body to many-body transitions and interactions, and few-body ionization as well as quantum metrology. © 2011 American Physical Society.

This paper is a critical study of contemporary Lexington, Virginia, examining issues of collective memory and heritage within this traditional "mecca" of Confederate remembrance. My reading of Lexington is the result of ten years of fieldwork in the town from 2004 to 2010 and is designed to highlight and critique the continued dominance of neo-Confederate forms of nationalism and masculinity within the town's tourist sites and on the campuses of its two colleges, Washington and Lee University (W & L) and the Virginia Military Institute (VMI). Lexington is perhaps best known for its association with the two most prominent Confederate "heroes" of the past, Generals Robert E. Lee and Stonewall Jackson. My extended critical analysis of Southern masculinity at both universities links these prevailing forms of Old South masculinity in Lexington. Finally, this paper highlights how recent demographic and political changes in the town have resulted in public campaigns that challenge the dominance of neo-Confederacy in Lexington.

Stoltzfus J.D.,University of Pennsylvania | Stoltzfus J.D.,Hollins University | Bart S.M.,University of Pennsylvania | Lok J.B.,University of Pennsylvania
PLoS Pathogens | Year: 2014

The infectious form of the parasitic nematode Strongyloides stercoralis is a developmentally arrested third-stage larva (L3i), which is morphologically similar to the developmentally arrested dauer larva in the free-living nematode Caenorhabditis elegans. We hypothesize that the molecular pathways regulating C. elegans dauer development also control L3i arrest and activation in S. stercoralis. This study aimed to determine the factors that regulate L3i activation, with a focus on G protein-coupled receptor-mediated regulation of cyclic guanosine monophosphate (cGMP) pathway signaling, including its modulation of the insulin/IGF-1-like signaling (IIS) pathway. We found that application of the membrane-permeable cGMP analog 8-bromo-cGMP potently activated development of S. stercoralis L3i, as measured by resumption of feeding, with 85.1±2.2% of L3i feeding in 200 μM 8-bromo-cGMP in comparison to 0.6±0.3% in the buffer diluent. Utilizing RNAseq, we examined L3i stimulated with DMEM, 8-bromo-cGMP, or the DAF-12 nuclear hormone receptor (NHR) ligand Δ7-dafachronic acid (DA)-a signaling pathway downstream of IIS in C. elegans. L3i stimulated with 8-bromo-cGMP up-regulated transcripts of the putative agonistic insulin-like peptide (ILP) -encoding genes Ss-ilp-1 (20-fold) and Ss-ilp-6 (11-fold) in comparison to controls without stimulation. Surprisingly, we found that Δ7-DA similarly modulated transcript levels of ILP-encoding genes. Using the phosphatidylinositol-4,5-bisphosphate 3-kinase inhibitor LY294002, we demonstrated that 400 nM Δ7-DA-mediated activation (93.3±1.1% L3i feeding) can be blocked using this IIS inhibitor at 100 μM (7.6±1.6% L3i feeding). To determine the tissues where promoters of ILP-encoding genes are active, we expressed promoter::egfp reporter constructs in transgenic S. stercoralis post-free-living larvae. Ss-ilp-1 and Ss-ilp-6 promoters are active in the hypodermis and neurons and the Ss-ilp-7 promoter is active in the intestine and a pair of head neurons. Together, these data provide evidence that cGMP and DAF-12 NHR signaling converge on IIS to regulate S. stercoralis L3i activation. © 2014 Stoltzfus et al.

In this paper, we look at what it means to 'eat Hawai'i' and examine how Hawai'i Regional Cuisine (HRC) imagines, produces, and consumes place through particular constructions of local foods. The term 'local' attaches to foods as a marker of numerous positive attributes such as seasonal, sustainable, and community-based. Drawing upon ongoing ethnographic research on Hawai'i Island, we examine spatial and discursive constructions of local and how this particular cuisine places itself in local food networks while simultaneously using place to localize itself within the Island's food networks. Using a case study approach to carefully contextualize localness, we show how Merriman's Restaurant and HRC complicate notions of alternative and local food systems in its discursive and material production and reproduction of Local food and locally grown food. © 2011 Copyright Taylor and Francis Group, LLC.

Kirkorian H.L.,University of Wisconsin - Madison | Choi K.,University of Wisconsin - Madison | Pempek T.A.,Hollins University
Child Development | Year: 2016

Researchers examined whether contingent experience using a touch screen increased toddlers' ability to learn a word from video. One hundred and sixteen children (24-36 months) watched an on-screen actress label an object: (a) without interacting, (b) with instructions to touch anywhere on the screen, or (c) with instructions to touch a specific spot (location of labeled object). The youngest children learned from contingent video in the absence of reciprocal interactions with a live social partner, but only when contingent video required specific responses that emphasized important information on the screen. Conversely, this condition appeared to disrupt learning by slightly older children who were otherwise able to learn words by passively viewing noninteractive video. Results are interpreted with respect to selective attention and encoding. © 2016 The Society for Research in Child Development, Inc.

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