Hokkaido Bunkyo University

Chuo-ku, Japan

Hokkaido Bunkyo University is a private university in Hokkaido, Japan, established in 1999. It has campuses in Eniwa and Sapporo. Its junior college division is coeducational. The predecessor of the school, a women's school, was founded in 1942. Wikipedia.

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Saito M.,Hokkaido Bunkyo University | Ohtsuka Y.,Hokkaido University
Rigakuryoho Kagaku | Year: 2017

[Purpose] Rehabilitation is important for clinics in community-based integrated care systems. The aim of this study was to clarify the perspectives of clinical rehabilitation of doctors, nurses, physical therapists and social workers (staff) working at the same clinic. [Subjects and Methods] We gave a lecture about rehabilitation and conducted questionnaire surveys of the staff before and after the lecture. Questionnaire responses were compared. [Results] Staff showed improved awareness of rehabilitation after the lecture. [Conclusion] These results suggest that rehabilitation education and training system at clinics is essential for staff. © 2017, Society of Physical Therapy Science (Rigaku Ryoho Kagakugakkai). All rights reserved.

Saito M.,Hokkaido Bunkyo University | Ohtsuka Y.,Hokkaido University | Wakabayashi H.,Yokohama City University
Rigakuryoho Kagaku | Year: 2017

[Purpose] The objective of this study was to determine the current state of awareness regarding rehabilitation, diagnosis and training among general practice residents. [Subjects and Methods] Eight residents were included in this study. Seven were part of a senior training program for family doctors and general practitioners, and one was a cardiovascular resident. The qualitative research involved conducting focus group interviews and then analyzing the results using Steps for Coding and Theorization. [Results] Four basic concepts were extracted from the interviews: the ability of general practitioners to implement rehabilitation, a weak connection to rehabilitation work, the results of attending lectures, and the state of rehabilitation training among general practice residents. [Conclusion] A rehabilitation training system is needed for residents who are expected to become family doctors or to assume similar duties. © 2017, Society of Physical Therapy Science (Rigaku Ryoho Kagakugakkai). All rights reserved.

Nakamura R.,Japan National Institute of Health Sciences | Adachi R.,Japan National Institute of Health Sciences | Itagaki Y.,Hokkaido Bunkyo University | Fukutomi Y.,Sagamihara National Hospital | And 2 more authors.
International Archives of Allergy and Immunology | Year: 2013

Background: We performed an in vitro elicitation test to determine the ability of different types of wheat-allergic patients' IgE to induce humanized mast cell activation after the addition of various time-treated acid-hydrolyzed wheat proteins (HWPs). Methods: The reactivity of heat- and various time-treated acid-hydrolyzed glutens (acid-HGs) and commercial acid-HWP (HWP1), using serum IgE from wheat allergy accompanied by skin and rhinoconjunctival sensitization to HWP1 in the facial soap, pediatric subjects with food allergy to native wheat, adult wheat-dependent exercise-induced anaphylaxis subjects, and nonatopic healthy subjects, was elucidated by dot blot and a luciferase assay-based in vitro elicitation test (EXiLE test). Results: Serum from subjects sensitized with HWP1 reacted only to acid-HGs (acid-HGs treated for 0.5-3 or 6 h), but not native gluten, in the results of the dot blot. In contrast, sera from pediatric subjects sensitized with native wheat reacted to native gluten more strongly and showed only slight reactions to 0.5- to 1-hour-treated acid-HGs. The results of the in vitro elicitation test showed that acid hydrolyzation of the gluten attenuated antigen-induced luciferase expression in a time-dependent manner for sera from native-wheat-sensitized pediatric subjects. On the other hand, in the sera from HWP1-sensitized subjects, acid hydrolyzation of the gluten for 0.5 h dramatically increased luciferase expression. Conclusions: Even after prolonged hydrolyzation, acid-HGs still retained the ability to activate mast cells in the case of HWP1-sensitized subjects. © 2012 S. Karger AG, Basel.

Kakizaki I.,Hirosaki University | Tatara Y.,Hirosaki University | Majima M.,Hokkaido Bunkyo University | Kato Y.,Hirosaki University | Endo M.,Hirosaki University
Archives of Biochemistry and Biophysics | Year: 2011

There has been no structural information about the core protein of salmon nasal cartilage proteoglycan although its physiological activities have been investigated. Internal amino acid sequencing using nano-LC/MS/MS revealed that the salmon proteoglycan was aggrecan. Primer walk sequencing based on the amino acid information determined that the salmon aggrecan cDNA is comprised of 4207 bp nucleotides predicted to encode 1324 amino acids with a molecular mass of 143,276. It exhibited significant similarities to predicted pufferfish aggrecan, zebrafish similar to aggrecan, zebrafish aggrecan, bovine aggrecan and human aggrecan isoform 2 precursor; whose amino acid identities were 56%, 55%, 49%, 31% and 30%, respectively. Salmon cartilage aggrecan had globular domains G1, G2 and G3 as in mammalian aggrecans. Neither the putative keratan sulfate attachment domain enriched with serine, glutamic acid and proline, nor the putative chondroitin sulfate attachment domain with repeating amino acid sequence containing serine-glycine, found in mammalian aggrecans were observed in salmon, however, random serine-glycine (or glycine-serine) sequences predicted to the sugar chain attachment sites were observed. Based on cDNA analysis and amino acid analysis after β-elimination, the ratio of serine attached to sugar chains was calculated to be approximately 37.7% of total serine, that is, 46 of 123 serine residues. © 2010 Elsevier Inc. All rights reserved.

Kohei Y.,Sapporo Medical University | Kohei Y.,Hokkaido Bunkyo University | Sumi A.,Sapporo Medical University | Kobayashi N.,Sapporo Medical University
Epidemiology and Infection | Year: 2016

We investigated the seasonality of age-specific tuberculosis (TB) in Japan. To allow the development of TB control strategies for different age groups we used a time-series analysis, including a spectral analysis and least squares method, to analyse the monthly age-specific numbers of newly registered cases of all forms of active TB in Japan from January 1998 to December 2013. The time-series data are reported in 10-year age groups: 0-9, 10-19, ... , 70-79, and ≥80 years. We defined the contribution ratio of the 1-year cycle, Q 1, as the contribution of the amplitude of a 1-year cycle to the whole amplitude of the time-series data. The Q 1 values in the age groups corresponding to adolescence and middle life (10-39 years) and old age (≥70 years) were high. The peaks in the active TB epidemics for the ≥70 years age group occurred in August and September, 1-2 months behind the peaks for the 10-39 years age group (June and July). An active TB epidemic might be attributable to travel by public transport and irregular employment in the 10-39 years age group and immune system suppression by low winter temperatures in the ≥70 years age group. © Cambridge University Press 2016.

PubMed | Ibaraki Prefectural University of Health Sciences, Hokkaido Bunkyo University, Sapporo Medical University and Senri Rehabilitation Hospital
Type: Journal Article | Journal: Journal of physical therapy science | Year: 2016

[Purpose] This study aimed to determine the reliability and validity of our standing balance assessment index using a hand-held dynamometer (the hand-held dynamometer assessment index) in stroke patients. [Subjects and Methods] The participants were 60 stroke patients with impaired standing balance. Intrarater and interrater reliabilities were evaluated employing the intraclass correlation coefficient. Criterion-related validity was evaluated by Spearmans rank correlation coefficient between the HHD assessment index and the functional balance scale. [Results] The intraclass correlation coefficient values obtained ranged from 0.91 to 0.98, and the correlation coefficient with the FBS was 0.83. [Conclusion] Our findings confirmed the reliability and validity of the hand-held dynamometer assessment index in stroke patients.

Fujiwara K.,Kanazawa University | Yaguchi C.,Hokkaido Bunkyo University
Journal of Electromyography and Kinesiology | Year: 2013

In bilateral shoulder flexion with the arms moving from the sides of the body to the horizontal level while standing, no preceding activation of the triceps surae (TS) with respect to focal muscles has been found. Considering that preceding activation would offer a useful indicator of anticipatory postural control, it was attempted to induce preceding activation by limiting the anterior displacement range of the center of foot pressure in the anteroposterior direction (CoPap). Subjects were 13 healthy young adults. The 50% anterior range of CoPap displacement caused by shoulder flexion was calculated, and the floor inclined by the subject's weight when CoPap extended beyond that range. Subjects were instructed not to incline the floor during shoulder flexion. Under the limitation condition, the ankle and knee joints plantarflexed and extended at 1.1°, respectively, with no hip movement; that is, the whole body inclined backward by pivoting at the ankle. This limitation resulted in preceding muscle activation of TS as well as erector spinae and biceps femoris, and no significant differences in onset time were seen between these muscles. These results demonstrated that by limiting CoPap anterior displacement, preceding activation of TS could be induced with backward inclination of the whole body. © 2013 Elsevier Ltd.

Yaguchi C.,Hokkaido Bunkyo University | Yaguchi C.,Kanazawa University | Fujiwara K.,Kanazawa University
Clinical Neurophysiology | Year: 2012

Objective: We investigated effects of attentional dispersion on sensory-motor processing of anticipatory postural control during unilateral arm abduction. Methods: Thirteen adults performed arm abduction under two types of attentional dispersion conditions. A target stimulus was presented with 30% probability in two- or three-positions. By cue signal presentation, subjects either focused their attention on one position or divided attention for two or three positions and abducted right arm for target stimulus. Event-related potentials and onset time of postural muscles were measured. Results: P1-N1 and N2 amplitudes decreased with attentional dispersion in both conditions, but P3 did not change. With attentional dispersion to three-positions, N2 latency increased and start of late CNV was delayed, and also the onset time of gluteus medius was late in correlation to the late CNV changings, with no changings in two-positions. Conclusions: With attentional dispersion, brain activation decreased in the area related to the sensory processing and especially in the stimulus discrimination area. With increasing attentional dispersion, the delay in motor preparation or anticipatory attention to target stimuli was related to the delay in stimulus discrimination and onset time of postural muscle activation. Significance: Effects of attentional dispersion on sensory-motor processing of anticipatory postural control were experimentally demonstrated. © 2011 International Federation of Clinical Neurophysiology.

Yoshida K.,Hokkaido University | Yoshida K.,Hokkaido Bunkyo University | Sawamura D.,Health Sciences University of Hokkaido | Inagaki Y.,Hokkaido University | And 3 more authors.
Neuroscience Letters | Year: 2014

Flow is the holistic experience felt when an individual acts with total involvement. Although flow is likely associated with many functions of the prefrontal cortex (PFC), such as attention, emotion, and reward processing, no study has directly investigated the activity of the PFC during flow. The objective of this study was to examine activity in the PFC during the flow state using functional near-infrared spectroscopy (fNIRS). Twenty right-handed university students performed a video game task under conditions designed to induce psychological states of flow and boredom. During each task and when completing the flow state scale for occupational tasks, change in oxygenated hemoglobin (oxy-Hb) concentration in frontal brain regions was measured using fNIRS. During the flow condition, oxy-Hb concentration was significantly increased in the right and left ventrolateral prefrontal cortex. Oxy-Hb concentration tended to decrease in the boredom condition. There was a significant increase in oxy-Hb concentration in the right and left dorsolateral prefrontal cortex, right and left frontal pole areas, and left ventrolateral PFC when participants were completing the flow state scale after performing the task in the flow condition. In conclusion, flow is associated with activity of the PFC, and may therefore be associated with functions such as cognition, emotion, maintenance of internal goals, and reward processing. © 2014 Elsevier Ireland Ltd.

Mineo H.,Hokkaido Bunkyo University | Amita N.,Hokkaido Bunkyo University | Kawawake M.,Hokkaido Bunkyo University | Higuchi A.,Hokkaido Bunkyo University
Biochimica et Biophysica Acta - Biomembranes | Year: 2013

We examined the effect of dicarboxylic acids having 0 to 6 hydrocarbons and their corresponding monocarboxylic or tricarboxylic acids in changing the osmotic fragility (OF) in rat red blood cells (RBCs). Malonic, succinic, glutaric and adipic acids, which are dicarboxylic acids with 1, 2, 3 and 4 straight hydrocarbons located between two carboxylic groups, decreased the OF in a concentration-dependent manner. Other long-chain dicarboxylic acids did not change the OF in rat RBCs. The benzoic acid derivatives, isophthalic and terephthalic acids, but not phthalic acid, decreased the OF in a concentration-dependent manner. Benzene-1,2,3-tricarboxylic acid, but not benzene-1,3,5-tricarboxylic acid, also decreased the OF in rat RBCs. On the other hand, monocarboxylic acids possessing 2 to 7 straight hydrocarbons and benzoic acid increased the OF in rat RBCs. In short-chain dicarboxylic acids, a limited number of hydrocarbons between the two carboxylic groups are thought to form a V- or U-shaped structure and interact with phospholipids in the RBC membrane. In benzene dicarboxylic and tricarboxylic acids, a part of benzene nucleus between the two carboxylic groups is thought to enter the plasma membrane and act on acyl-chain in phospholipids in the RBC membrane. For dicarboxylic and tricarboxylic acids, limited numbers of hydrocarbons in molecules are speculated to enter the RBC membrane with the hydrophilic carboxylic groups remaining outside, stabilizing the structure of the cell membrane and resulting in an increase in osmotic resistance in rat RBCs. © 2013 Elsevier B.V.

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