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Hempstead, NY, United States

Hofstra University is a private, non-profit, nonsectarian institution of higher learning located in the Village of Hempstead, New York, United States, about 7 miles east of New York City. It originated in 1935 as an extension of New York University called "Nassau College – Hofstra Memorial of New York University at Hempstead, Long Island"; in 1937, the institution separated from NYU and gained independence as Hofstra College, and in 1963, Hofstra College gained university status. Comprising ten schools, including a School of Medicine and a School of Law, Hofstra is noted for a series of prominent Presidential conferences, as well as being selected to host United States Presidential Debates in 2008 and 2012. The university organizes a wide range of other international academic conferences , holds an annual Shakespeare festival in its own replica of the Globe Theatre, and has both an arboretum and bird sanctuary. Wikipedia.

Israeli R.,Hofstra University
Aesthetic surgery journal / the American Society for Aesthetic Plastic surgery | Year: 2011

Acellular dermal matrices (ADM) are becoming an integral component of immediate implant-based breast reconstruction, providing inferolateral coverage and support of the implant. Currently, five ADM products are available on the market for this purpose. Although their application has resulted in improved aesthetic results with low complication rates, the clinical performance of ADM when radiotherapy is a component of breast cancer treatment has yet to be defined. In this article, we present a thorough review of the current literature on the performance of ADM in the setting of radiotherapy from both animal and human studies, including our own experience with two proprietary ADM products. The other three products have little literature documenting their application for this type of reconstruction, and further studies specifically evaluating the performance of all ADM formulations in the setting of radiotherapy are still needed. Source

Israeli R.,Hofstra University
Plastic and reconstructive surgery | Year: 2012

Acellular dermal matrices have been used in breast surgery for a decade. They are widely used in implant-based breast reconstruction to provide coverage of the inferolateral aspects of the prosthesis. Numerous benefits have been reported with this approach including improved fold control, better support and control of the implant pocket with concomitant reduced risk of malposition, and improved lower pole expansion. Seroma, infection, mastectomy skin necrosis, and expander/implant loss are the most commonly reported complications with this approach, and the incidences vary widely among studies. Patient selection and adherence to established intraoperative technique principles related to acellular dermal matrix use are both critical to minimizing the risk of complications. Acellular dermal matrices are also being used in aesthetic breast surgery, revision breast surgery, and nipple reconstruction, but clinical experience is limited. This article reviews the complications associated with the use of matrices in breast surgery from the published literature. Source

Catalano A.,Hofstra University
Journal of Documentation | Year: 2013

Purpose: The purpose of this review is to draw out patterns of information seeking behavior of graduate students as described in the empirical research published from 1997 to the present. Design/methodology/approach: A systematic search of databases for studies on information behavior and graduate students was employed in order to retrieve studies for a systematic review. Common themes that emerged from the literature were synthesized into a discussion of behavior patterns. Additionally a study quality analysis was conducted for all retrieved studies using a critical appraisal checklist for library and information research. Findings: This review revealed that graduate students begin their research on the internet much like any other information seeker, consult their faculty advisors before other people, and use libraries in diverse ways depending on the discipline studied. Additionally differences were noted between international and home students, and doctoral and master's students. Practical implications: The findings of this review indicate that information behavior research conducted on graduate students should delineate between masters' and doctoral students. Further, the findings may inform both academic librarian and faculty practice as to how to assist students with their research by helping them to understand how students typically approach research and how other institutions address common issues with special populations, such as non-native speakers and distance learners. Originality/value: No comprehensive review of information behavior studies, encompassing only the behaviors of graduate students has been conducted to date. © Emerald Group Publishing Limited. Source

Harden C.L.,Hofstra University | Harden C.L.,Comprehensive NeuroScience | Pennell P.B.,Harvard University
The Lancet Neurology | Year: 2013

Complex, multidirectional interactions between hormones, seizures, and the medications used to control them can present a challenge for clinicians treating patients with epilepsy. Many hormones act as neurosteroids, modulating brain excitability via direct binding sites. Thus, changes in endogenous or exogenous hormone levels can affect the occurrence of seizures directly as well as indirectly through pharmacokinetic effects that alter the concentrations of antiepileptic drugs. The underlying structural and physiological brain abnormalities of epilepsy and the metabolic activity of antiepileptic drugs can adversely affect hypothalamic and gonadal functioning. Knowledge of these complex interactions has increased and can now be incorporated in meaningful treatment approaches for men and women with epilepsy. © 2013 Elsevier Ltd. Source

Sharaf R.N.,Hofstra University | Sharaf R.N.,Stanford University | Ladabaum U.,Stanford University
American Journal of Gastroenterology | Year: 2013

Objectives: Fecal occult blood testing (FOBT) and sigmoidoscopy are proven to decrease colorectal cancer (CRC) incidence and mortality. Sigmoidoscopy's benefit is limited to the distal colon. Observational data are conflicting regarding the degree to which colonoscopy affords protection against proximal CRC. Our aim was to explore the comparative effectiveness and cost-effectiveness of colonoscopy vs. sigmoidoscopy and alternative CRC screening strategies in light of the latest published data. Methods: We performed a contemporary cost-utility analysis using a Markov model validated against data from randomized controlled trials of FOBT and sigmoidoscopy. Persons at average CRC risk within the general US population were modeled. Screening strategies included those recommended by the United States (US) Preventive Services Task Force, including colonoscopy every 10 years (COLO), flexible sigmoidoscopy every 5 years (FS), annual fecal occult blood testing, annual fecal immunochemical testing (FIT), and the combination FS/FIT. The main outcome measures were quality-adjusted life-years (QALYs) and costs. Results: In the base case, FIT dominated other strategies. The advantage of FIT over FS and COLO was contingent on rates of uptake and adherence that are well above current US rates. Compared with FIT, FS and COLO both cost <50,000/QALY gained when FIT per-cycle adherence was <50%. COLO cost 56,800/QALY gained vs. FS in the base case. COLO cost <100,000/QALY gained vs. FS when COLO yielded a relative risk of proximal CRC of <0.5 vs. no screening. In probabilistic analyses, COLO was cost-effective vs. FS at a willingness-to-pay threshold of 100,000/QALY gained in 84% of iterations. Conclusions: Screening colonoscopy may be cost-effective compared with FIT and sigmoidoscopy, depending on the relative rates of screening uptake and adherence and the protective benefit of colonoscopy in the proximal colon. Colonoscopy's cost-effectiveness compared with sigmoidoscopy is contingent on the ability to deliver ∼50% protection against CRC in the proximal colon. © 2013 by the American College of Gastroenterology. Source

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