Ho Chi Minh City, Vietnam
Ho Chi Minh City, Vietnam

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Hai T.H.,Ho Chi Minh City Institute of Physic | Phuc L.H.,Ho Chi Minh City Institute of Physic | Vinh L.K.,Ho Chi Minh City Institute of Physic | Long B.D.,Ho Chi Minh City Institute of Physic | And 6 more authors.
International Journal of Nanotechnology | Year: 2011

This paper presents the synthesis and properties of magnetic silica-coated Fe3O4 nanoparticles. Uncoated Fe3O4 nanoparticles with an average diameter of 9-16 nm and saturation magnetisation of around 66 emu/g were first prepared by co-precipitation method. After being coated by SiO2 using the sol-gel method, the diameters of the coated particles ranged from 29 nm to 230 nm and their corresponding saturation magnetisation was reduced to 29 emu/g. The magnetic coated nanoparticles were attached to the monoclonal antibodies of HPV18 and E. coli O157:H7. The TG/DTA analyses indicated that antibodies were attached to the magnetic nanoparticles. The obtained results revealed that magnetic SiO2-coated Fe 3O4 nanoparticles can be a promising candidate for the diagnosis of cervical cancer at an early stage with high accuracy. Copyright © 2011 Inderscience Enterprises Ltd.

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