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Riches O.,Arup | Wong K.Y.,HKSAR | Yeung N.,Arup
Long Span Bridges and Roofs - Development, Design and Implementation | Year: 2013

The New Forth Crossing, currently being constructed over the Forth Estuary will be 2.7km in length and will include the world's longest three tower cable stayed bridge. To implement a state-of-the-art Inspection and Maintenance System on this bridge a fully integrated Structural Health Monitoring System (SHMS) will be installed to monitor performance, give advanced warning of structural problems, and allow the planning and programming of a targeted inspection, intervention and maintenance regime. Comprising approximately one thousand sensors the SHMS will monitor, archive and process the environmental conditions, bridge actions and the associated effects and enable the diagnosis of structural problems and the prognosis of the future service life of the bridge. Source


Mok T.S.K.,Chinese University of Hong Kong | Hsia T.-C.,China Medical University at Taichung | Tsai C.-M.,Taipei Veterans General Hospital | Tsang K.,HKSAR | And 8 more authors.
Asia-Pacific Journal of Clinical Oncology | Year: 2011

Aim: The phase III AVAiL study evaluated the efficacy and safety of the anti-vascular epidermal growth factor agent bevacizumab combined with platinum-based chemotherapy as first-line treatment in patients with advanced non-small-cell lung cancer (NSCLC). We report the results of a preplanned analysis of Asian patients enrolled in AVAiL. Methods: Patients with recurrent or advanced non-squamous NSCLC were randomized to receive bevacizumab 7.5mg/kg, bevacizumab 15mg/kg or placebo, plus cisplatin 80mg/m2 and gemcitabine 1250mg/m2 for up to six cycles, followed by bevacizumab or placebo until disease progression. An exploratory analysis was undertaken to assess efficacy and safety in an Asian subgroup. Results: Of the 1043 patients enrolled, 105 were Asian and were included in the subgroup analysis. Progression-free survival was 8.5months (95% CI 7.3-10.8) in the bevacizumab 15-mg/kg group, 8.2 (95% CI 6.6-11.7) in the 7.5-mg/kg group and 6.1 (95% CI 5.1-8.0) in the placebo group. Median overall survival in the 7.5-mg/kg bevacizumab group was prolonged compared with placebo group (HR 0.46; 95% CI 0.22-0.97). Nausea was the most common adverse event, occurring at similar rates (ranging from 69-76%) in all study groups. Hypertension was the most common adverse event of special interest, seen in 29, 55 and 16% of patients in the 7.5-mg/kg and 15-mg/kg bevacizumab and placebo groups, respectively. Conclusion: Study results strongly suggest that bevacizumab at a dose of 7.5mg/kg improves the duration of overall survival when combined with cisplatin-gemcitabine in Asian patients. Bevacizumab was well tolerated in this patient group. © 2011 Blackwell Publishing Asia Pty Ltd. Source


Zheng J.,South China University of Technology | Zhong L.,Guangdong Provincial Environmental Monitoring Center | Wang T.,Hong Kong Polytechnic University | Louie P.K.K.,HKSAR | Li Z.,South China University of Technology
Atmospheric Environment | Year: 2010

The ambient air quality monitoring data of 2006 and 2007 from a recently established Pearl River Delta (PRD) regional air quality monitoring network are analyzed to investigate the characteristics of ground-level ozone in the region. Four sites covering urban, suburban, rural and coastal areas are selected as representatives for detailed analysis in this paper. The results show that there are distinct seasonal and diurnal cycles in ground-level ozone across the PRD region. Low ozone concentrations are generally observed in summer, while high O3 levels are typically found in autumn. The O3 diurnal variations in the urban areas are larger than those at the rural sites. The O3 concentrations showed no statistically significant difference between weekend and weekdays in contrast to the findings in many other urban areas in the world. The average ozone concentrations are lower in urban areas compared to the sites outside urban centers. Back trajectories are used to show the major air-mass transport patterns and to examine the changes in ozone from the respective upwind sites to a site in the center of the PRD (Wanqingsha). The results show higher average ozone concentrations at the upwind sites in the continental and coastal air masses, but higher 1 h-max O3 concentrations (by 8-16 ppbv) at the center PRD site under each of air-mass category, suggesting that the ozone pollution in the PRD region exhibits both regional and super-regional characteristics. © 2009 Elsevier Ltd. All rights reserved. Source


Zhong L.J.,Guangdong Provincial Environmental Monitoring Center | Louie P.K.K.,HKSAR | Zheng J.Y.,South China University of Technology | Wai K.M.,HKSAR | And 5 more authors.
Aerosol and Air Quality Research | Year: 2013

In November 2005 the Guangdong and Hong Kong governments established the Pearl River Delta regional air quality monitoring network ("PRD RAQMN"), which represented the first joint regional air pollution and reporting effort in this rapidly developing and heavy-polluted area in southern China. This project has recorded the air quality trends during the 11th Five-Year Plan (FYP), implemented between 2006 and 2010, and will continue to do so throughout the period of economic development and stringent emission control of coal-fired power plants and vehicles that are part of the 12th FYP, to be implemented between 2011 and 2015. The PRD RAQMN serves as a role model for cooperation among local administrative authorities, as well as for the joint prevention and management of air pollution. The PRD RAQMN demonstrates that regional collaboration is critical to address the air pollution problems that China faces in a more effective manner. © Taiwan Association for Aerosol Research. Source


Shing C.K.,City University of Hong Kong | Wu C.M.L.,City University of Hong Kong | Chen J.W.J.,HKSAR | Yuen C.S.,HKSAR | Tsui R.Y.C.,HKSAR
HKIE Transactions Hong Kong Institution of Engineers | Year: 2012

Biogenic sulfuric acid (BSA) attack against concrete structures has been reported for many years. This particular attack has been causing severe damages to structures with closed environments such as covered sedimentation tanks in sewage treatment plants. It is believed that BSA attack is the major cause of sewage concrete structure degradation. In order to inhibit the attack caused by BSA, numerous protective methods had been attempted. Measures such as epoxy coating, acidic inhibitors, admixtures were explored. Some accelerated tests were established to evaluate such attacks. In this paper, some commonly used testing techniques and methods are reviewed. The test results from an accelerated laboratory test established for this study on various concrete protection systems are presented and an in-situ test plan on coated concrete samples at a sewage treatment plant in Hong Kong is also outlined. © The Hong Kong Institution of Engineers. Source

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