Hiroshima University | Date: 2016-08-23
An object of the present invention is to provide a method of detecting a nucleic acid binding protein and a method of screening for a binding inhibitor or promoter for a nucleic acid binding protein. According to the present invention, there is provided a method of detecting binding between a nucleic acid and a nucleic acid binding protein, comprising determining the degree of structural change in a nucleic acid complex having at least two nucleic acid duplex moieties.
Chugoku Electric Power Co., Hiroshima University and Toyo Koatsu Co. | Date: 2017-01-11
A heat exchanger includes: a flow passage unit arranged with a plurality of planar flow passage bodies each arranged with two flow passages adjacent to each other in a same plane, the plurality of the planar flow passage bodies being layered in an intersecting direction that intersects with the plane, and in two of the planar flow passage bodies adjacent in the intersecting direction of the plurality of the layered planar flow passage bodies, each one of two flow passage ports in both ends of each of the flow passages of one of the planar flow passage bodies is connected to each one of two flow passage ports in both ends of each of the flow passages of another of the planar flow passage bodies; and a high-pressure pipe that covers an outside of the flow passage unit.
Hiroshima University | Date: 2017-01-11
Disclosed is the provision of a method for assisting the detection of pancreatic cancer, the method assisting the detection of pancreatic cancer with high accuracy. In the method for assisting the detection of pancreatic cancer, the amounts of (1) miR-122-5p and (2) at least one miRNA selected from the group consisting of miR-16-5p, miR-19b-3p and miR-25-3p, all of which are contained in a test sample separated from a living body, are used as indicators. A larger amount of miR-122-5p and a smaller amount of at least one miRNA selected from the group consisting of miR-16-5p, miR-19b-3p and miR-25-3p than those in a healthy individual indicates that the living body is more likely to have developed pancreatic cancer.
Chugoku Electric Power Co., Hiroshima University and Toyo Koatsu Co. | Date: 2017-01-11
A double tube and the like includes: a cylindrical outer tube; a cylindrical inner tube including a helical protrusion in an outer circumferential surface, the inner tube being provided inside the outer tube; and a helical flow passage forming member that forms a helical flow passage inside the inner tube, the helical flow passage forming member being provided inside the inner tube.
Hiroshima University, Hoshikei Kinzoku Kogyo Co., Japan Construction Machinery And Construction Association, Akashin Corporation and Sankyo Tateyama Inc. | Date: 2017-03-29
Provided is a scissors-type retractable structure 1 which is extendable in an extension direction. The retractable structure 1 includes at least one scissors frame 4 including a plurality of frame elements 3 each comprised of two frame members 2 pin-connected to each other at central portions of the frame members 2, and formed by pin-connecting the plurality of frame elements 3 to each other at end portions of the frame members 2. When the scissors frame 4 is in an extended state, part of the frame members 2 forming the frame elements 3 and positioned on a near side are linearly coupled to each other, and the other part of the frame members 2 forming the frame elements 3 and positioned on a far side are linearly coupled to each other, thereby causing upper surfaces of the frame members 2 to form a continuous flat surface.
Hiroshima University | Date: 2017-06-21
The present application relates to a method for determining a risk of preterm birth and/or low birth weight of a pregnant female comprising measuring a galectin-3 (Gal-3) level in a blood, plasma, or serum sample obtained from the pregnant female, or a kit or marker which may be used in the method. The present application also relates to a medicament effective to reduce a risk of preterm birth and/or low birth weight, a pharmaceutical composition comprising the medicament, or a method for reducing a risk of preterm birth and/or low birth weight of a pregnant female comprising administering the medicament or the pharmaceutical composition to the pregnant female.
Hiroshima University and JMS Co. | Date: 2017-06-28
Provided is a gas storing mask which, with a simple configuration, allows a reduction in feeling of discomfort given to a patient. An oxygen delivering mask (1a) includes a first sheet (2) and a second sheet (3), oxygen supplied from outside the oxygen delivering mask (1a) being stored in a gas storing part (4) formed between the first sheet (2) and the second sheet (3).
Toyoda Iron Works Co. and Hiroshima University | Date: 2017-05-31
A wind power generation device that generates power via bending deformation of a piezoelectric element as a result of vibrations of a power generation unit due to wind, wherein damage due to an increase in amplitude of the vibrations at the time of strong wind is suppressed and power is generated stably and efficiently by wind in a wide wind velocity range without impairing power generation performance in a normal wind velocity range. A lower end portion of a power generation unit (14) is connected to a slidably fitted portion (30) of a tension adjustment mechanism (20). When a strong wind blows, the slidably fitted portion (30) is moved by a lifting power F of a wing-like portion (38) from a first position (lifted end) to a second position (lowered end) as a result of an increase in wind velocity, resulting in greater tensile force of the power generation unit (14). Thus, the power generation unit (14) is suppressed from being damaged due to an excess amplitude of the vibrations of the power generation unit (14) when a strong wind blows. When a strong wind does not blow, the slidably fitted portion (30) is held at the first position, where the power generation unit (14) has small tensile force and can vibrate with a greater amplitude, enabling efficient generation of power by bending deformation of a piezoelectric film (46).
Hiroshima University and Teijin Film Solutions Ltd | Date: 2017-07-12
The polyester sheet in accordance with an aspect of the present invention contains crystals of polyester which is a polycondensate of polyvalent carboxylic acid and polyalcohol. The polyester sheet contains nano-oriented crystals which contain crystals of polyester in each of which a polymer chain is highly oriented and each of which has a crystal size of 50 nm or less. A heatproof temperature of the polyester sheet is higher than a temperature that is lower than an equilibrium melting point of the polyester by 80C, and a melting point of the polyester sheet is higher than a temperature that is lower than the equilibrium melting point of the polyester by 40C.
Itoh T.,Hiroshima University
Chemical Reviews | Year: 2012
Considerable progress has been made during these three or four decades in the accumulation of the anomalous emission spectral data of organic molecules, including the emission from higher excited states. In particular, experiments in a supersonicjet expansion provided information on the intrinsic photophysical properties of cooled and isolated molecules in which the Boltzmann distribution is almost negligible. Organic molecules showing emission from higher excited states form unique systems to which a number of modern techniques should be applied to obtain more detailed information on their photophysical properties. These data will provide useful information for understanding the dynamical behavior of isolated molecules in their excited states. There seems to be at least three mechanisms for occurrence of fluorescence from higher excited states: (A) the fluorescence occurs through the thermal repopulation of the lower excited state, e.g., S1; (B) it occurs via the reverse internal conversion from the lower singlet state under collision-free conditions; and (C) it occurs directly from the higher singlet state without involvement of the fluorescence component via the reverse internal conversion from the lower singlet state, i.e., prompt fluorescence. In case (C), the internal conversion rate from the higher singlet state to the lower state is considered to be slow enough to compete with the fluorescence from the higher state. In terms of phosphorescence from higher triplet states, there is mainly one mechanism corresponding to case (A) for the occurrence of the emission, except for the case of halogenated benzenes, for which dual phosphorescence from the 3(∏, ∏*) and 3 (∏, σ*) states was observed. That is, in most cases the phosphorescence from the higher triplet excited state occurs as the result of the thermal activation of the lower triplet state. Further, at present only the T2 phosphorescence is known as an observed emission from the higher triplet e cited state. © 2012 American Chemical Society.