Hiroshima-shi, Japan

Hiroshima Shudo University

Hiroshima-shi, Japan

Hiroshima Shudo University is a private university in Hiroshima, Hiroshima, Japan. The predecessor of the school, Hiroshima Domain's Han school, was founded in 1725. It was chartered as a junior college in 1952 and became a four-year college in 1960. The school adopted the present name in 1973. It was announced in March 2013 that Shudo Gakuen, the educational corporation behind the university, would merge in April 2015 with Suzugamine Gakuen, the educational corporation behind Suzugamine Women's College. Wikipedia.

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Takahama T.,Hiroshima City University | Sakai S.,Hiroshima Shudo University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2017

Differential Evolution (DE) has been successfully applied to various optimization problems. The performance of DE is affected by algorithm parameters such as a scaling factor F and a crossover rate CR. Many studies have been done to control the parameters adaptively. One of the most successful studies on controlling the parameters is JADE. In JADE, the values of each parameter are generated according to one probability density function (PDF) which is learned by the values in success cases where the child is better than the parent. However, search performance might be improved by learning multiple PDFs for each parameter based on some characteristics of search points. In this study, search points are divided into plural groups according to the rank of their objective values and the PDFs are learned by parameter values in success cases for each group. The advantage of JADE with the group-based learning is shown by solving thirteen benchmark problems. © Springer International Publishing AG 2017.

Kawamura K.,Hiroshima Shudo University | Maurel M.-C.,CNRS Systematics, Biodiversity and Evolution Institute
Origins of Life and Evolution of Biospheres | Year: 2017

Here we overview the chemical evolution of RNA molecules from inorganic material through mineral-mediated RNA formation compatible with the plausible early Earth environments. Pathways from the gas-phase reaction to the formation of nucleotides, activation and oligomerization of nucleotides, seem to be compatible with specific environments. However, how these steps interacted is not clear since the chemical conditions are frequently different and can be incompatible between them; thus the products would have migrated from one place to another, suitable for further chemical evolution. In this review, we summarize certain points to scrutinize the RNA World hypothesis. © 2017 Springer Science+Business Media Dordrecht

Rozin P.,University of Pennsylvania | Moscovitch M.,University of Toronto | Imada S.,Hiroshima Shudo University
Neuropsychologia | Year: 2016

We present evidence that individuals from East or South Asian cultures (Japanese college students in Japan and East or South Asian born and raised college students in the USA) tend to exhibit default thinking that corresponds to right hemisphere holistic functions, as compared to Caucasian individuals from a Western culture (born and raised in the USA). In two lateralized tasks (locating the nose in a scrambled face, and global-local letter task), both Asian groups showed a greater right hemisphere bias than the Western group. In a third lateralized task, judging similarity in terms of visual form versus functional/semantic categorizations, there was not a reliable difference between the groups. On a classic, ambiguous face composed of vegetables, both Eastern groups displayed a greater right hemisphere (holistic face processing) bias than the Western group. These results support an “East - Right Hemisphere, West - Left Hemisphere” hypothesis, as originally proposed by Ornstein (1972). This hypothesis is open as to the degree to which social-cultural forces were involved in hemispheric specialization, or the opposite, or both. Our aim is to encourage a more thorough analysis of this hypothesis, suggesting both lateralization studies corresponding to documented East-West differences, and East-West studies corresponding to lateralization differences. © 2016 Elsevier Ltd

Ogata T.,Waseda University | Ogata T.,Hiroshima Shudo University | Oishi Y.,Kumamoto University | Higuchi M.,Waseda University | Muraoka I.,Waseda University
Biochemical and Biophysical Research Communications | Year: 2010

This study investigated regulation of autophagy in slow-twitch soleus and fast-twitch plantaris muscles in fasting-related atrophy. Male Fischer-344 rats were subjected to fasting for 1, 2, or 3 days. Greater weight loss was observed in plantaris muscle than in soleus muscle in response to fasting. Western blot analysis demonstrated that LC3-II, a marker protein for macroautophagy, was expressed at a notably higher level in plantaris than in soleus muscle, and that the expression level was fasting duration-dependent. To identify factors related to LC3-II enhancement, autophagy-related signals were examined in both types of muscle. Phosphorylated mTOR was reduced in plantaris but not in soleus muscle. FOXO3a and ER stress signals were unchanged in both muscle types during fasting. These findings suggest that preferential atrophy of fast-twitch muscle is associated with induction of autophagy during fasting and that differences in autophagy regulation are attributable to differential signal regulation in soleus and plantaris muscle. © 2010 Elsevier Inc. All rights reserved.

Takahama T.,Hiroshima City University | Sakai S.,Hiroshima Shudo University
2013 IEEE Congress on Evolutionary Computation, CEC 2013 | Year: 2013

We have proposed to utilize a rough approximation model, which is an approximation model with low accuracy and without learning process, to reduce the number of function evaluations in unconstrained optimization. Although the approximation errors between the true function values and the approximation values estimated by the rough approximation model are not small, the rough model can estimate the order relation of two points with fair accuracy. In order to use this nature of the rough model, we have proposed estimated comparison which omits the function evaluations when the result of the comparison can be judged by approximation values. In this study, we propose to utilize the estimated comparison in constrained optimization and propose the εDEkr, which is the combination of the ε constrained method and the estimated comparison using kernel regression. The εDEkr is a very efficient constrained optimization algorithm that can find high-quality solutions in a very small number of function evaluations. It is shown that the εDEkr can find near optimal solutions stably in a very small number of function evaluations compared with various other methods on well-known nonlinear constrained problems. © 2013 IEEE.

Takahama T.,Hiroshima City University | Sakai S.,Hiroshima Shudo University
IEEE International Conference on Fuzzy Systems | Year: 2011

Differential Evolution (DE) is a newly proposed evolutionary algorithm. DE is a stochastic direct search method using a population or multiple search points. DE has been successfully applied to optimization problems including nonlinear, non-differentiable, non-convex and multimodal functions. However, the performance of DE degrades in problems having strong dependence among variables, where variables are related strongly to each other. In this study, we propose to utilize partition entropy given by fuzzy clustering for solving the degradation. It is thought that a directional search is desirable when search points are distributed with bias. Thus, when the entropy is low, algorithm parameters can be controlled to make the directional search. Also, we propose to use a species-best strategy for improving the efficiency and the robustness of DE. The effect of the proposed method is shown by solving some benchmark problems. © 2011 IEEE.

Iwata H.,Fukuoka Institute of Technology | Okada K.,Hiroshima Shudo University
Environmental Economics and Policy Studies | Year: 2014

Our study empirically investigates the effects of the Kyoto Protocol’s quantified emission limitation or reduction commitments on various greenhouse gas (GHG) emissions such as carbon dioxide (CO2), methane (CH4), nitrous oxide (N2O), and other greenhouse gases consisting of hydrofluorocarbons (HFCs), perfluorocarbons (PFCs), and sulfur hexafluoride (SF6). These GHG emissions are considered to be the main source of global warming issues, and 39 countries approved to meet the commitments by ratifying the Kyoto Protocol. Our empirical analysis is based on the Stochastic Impacts by Regression on Population, Affluence, and Technology (STIRPAT) model, the stochastic version of the IPAT model, using the data of 119 countries from 1990 to 2005. Our main findings are that the effects of the commitments to the Kyoto Protocol are (1) significantly negative for the cases of CO2and CH4emissions, (2) not significant for the case of N2O emissions, and (3) significantly positive for the case of other greenhouse gas emissions. These results have important policy implications for global warming issues. © 2012, Springer.

RNA played a central role in the emergence of the first life-like system on primitive Earth since RNA molecules contain both genetic information and catalytic activity. However, there are several drawbacks regarding the RNA world hypothesis. Here, I briefly discuss the feasibility of the RNA world hypothesis to deduce the RNA functions that are essential for forming a life-like system. At the same time, I have conducted a conceptual analysis of the characteristics of biosystems as a useful approach to deduce a realistic life-like system in relation to the definition of life. For instance, an RNA-based life-like system should possess enough stability to resist environmental perturbations, by developing a cell-like compartment, for instance. Here, a conceptual viewpoint is summarized to provide a realistic life-like system that is compatible with the primitive Earth environment and the capabilities of RNA molecules. According to the empirical and conceptual analysis, I propose the hypothesis that the first life-like system could have initiated from only two genes. © 2016 by the authors; licensee MDPI, Basel, Switzerland.

Hiraki S.,Hiroshima Shudo University
Journal of Japan Industrial Management Association | Year: 2010

When determining the sequence of a mixed-model assembly line, the following two objectives are usually considered: (1) leveling the load (total assembly time) for each process within the assembly line, and (2) maintaining a constant rate of use of each part in the line. For the first objective, we usually determine the sequence that minimizes maximum work congestion. For the second objective, a sequence is selected in which the quantity used per hour (i.e. consumption speed) of each part in the mixed-model assembly line is kept as constant as possible. Some studies have considered these two objectives simultaneously. In this paper, from the standpoint of supply chain management (SCM), we propose a new sequencing method that considers not only the two aforementioned traditional objectives, but also a third objective, that is, shortening the delivery time to a dealer when the final products are delivered by car-carriers. We propose an approach utilizing a two-stage sequencing method. In Stage 1, to maintain a constant rate of parts usage and meet the date of delivery, we divide the production period into shorter periods, and determine the production volume of each product for each period. Next, in Stage 2, we establish a production schedule for each divided period that realizes smoother production in the assembly line. We display numerical examples to explain and clarify the effectiveness of the proposed sequencing procedure.

Kawamura K.,Hiroshima Shudo University
Biochimie | Year: 2012

Following the discovery of ribozymes, the "RNA world" hypothesis has become the most accepted hypothesis concerning the origin of life and genetic information. However, this hypothesis has several drawbacks. Verification of the hypothesis from different viewpoints led us to proposals from the viewpoint of the hydrothermal origin of life, solubility of RNA and related biopolymers, and the possibility of creating an evolutionary system comparable to the in vitro selection technique for functional RNA molecules based on molecular biology. © 2011 Elsevier Masson SAS. All rights reserved.

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