Hindustan University is a university of engineering headquartered in Chennai, India. It was founded in 1985 by K. C. G. Verghese as Hindustan College of Engineering and was granted university status from the University Grants Commission in 2008 as the Hindustan Institute of Technology and Science , which it still uses as a subtitle. Wikipedia.
Abraham S.,Hindustan University
Asian Journal of Chemistry | Year: 2017
As metal oxide nanoparticles are widely used in biomedical field the interaction between bovine serum albumin (BSA) and Al2O3 nanoparticles and the effect of Al2O3 nanoparticles on the conformation of bovine serum albumin has been analyzed by various spectroscopic techniques. With increasing concentrations of Al2O3 nanoparticles in bovine serum albumin a shift in emission maximum, change in fluorescence intensity and change in lifetimes were observed compared to the emission maximum, fluorescence intensity and lifetimes of bovine serum albumin. Fluorescence emission spectra showed a blue shift with increasing concentrations of Al2O3 nanoparticles in bovine serum albumin which is indicative of increasing hydrophobicity. These studies showed that Al2O3 nanoparticles induced conformational changes in the structure of bovine serum albumin. © 2017, Chemical Publishing Co. All rights reserved.
Jeyapoovan T.,Hindustan University |
Murugan M.,B.S. Abdur Rahman University
Measurement: Journal of the International Measurement Confederation | Year: 2013
Surface roughness is an important factor in determining the satisfactory functioning of the machined components. Conventionally the surface roughness measurement is done with a stylus instrument. Since this measurement process is intrusive and is of contact type, it is not suitable for online measurements. There is a growing need for a reliable, online and non-contact method for surface measurements. Over the last few years, advances in image processing techniques have provided a basis for developing image-based surface roughness measuring techniques. Based upon the vision system, novel methods used for human identification in biometrics are used in the present work for characterization of machined surfaces. The Euclidean and Hamming distances of the surface images are used for surface recognition. Using a CCD camera and polychromatic light source, low-incident-angle images of machined surfaces with different surface roughness values were captured. A signal vector was generated from image pixel intensity and was processed using MATLAB software. A database of reference images with known surface roughness values was established. The Euclidean and Hamming distances between any new test surface and the reference images in the database were used to predict the surface roughness of the test surface. © 2013 Elsevier Ltd.
Prakash A.,Hindustan University
International Journal of Network Security | Year: 2014
Most existing computer and network systems authenticate a user only at the initial login session. This could be a critical security weakness, especially for high-security systems because it enables an impostor to access the system resources with the initial access permission. To address this security flaw, Continuous authentication of the user is necessary, to continuously monitors and authenticates the user throughout the session. Existing continuous authentication schemes primarily uses hard biometric traits, which is inconvenient to the user. To mitigate this problem, a new continuous user authentication scheme is designed to authenticate the user irrespective of their posture in front of the system. The system continuously monitors the user by using soft biometrics (color of user's clothing and facial skin) along with hard biometrics. It automatically registers soft biometric traits every time the user logs in and fuses soft biometric matching with the conventional face biometric authentication.
Balasubramaniam K.,Hindustan University
Procedia Computer Science | Year: 2015
Ontology is a way to represent the domain knowledge into a human understandable and machine readable format. It is used as one of the major knowledge representation mechanism for semantic web. Introducing the ontology knowledge provides more relevant search results for the users information need. To deal with uncertain information, the mechanism supported by the regular ontology may not be adequate and the requirement for new technique arises. Fuzzy based methods are the proven methods to interpret the uncertain information. The combination of Fuzzy and Ontology based information retrieval provides better results as they mainly deal with the semantics and the uncertainty of information. Keyword matching is one another widely used method which matches the input keywords with the existing information domain to find the best match results. When the input queries are complex the fuzzy ontology based information retrieval which respects the user's keyword and the domain produces more accurate results. This work enlarges the fuzzy ontology knowledge results along with the input queries and keyword matching. The given algorithm is a hybrid technique based on matching extracted instances from the input queries and in information domain. Overall, compared to the existing query models supported by fuzzy ontology or keyword based models the hybrid ontology with keyword matching is sufficient and easy way to retrieve the documents in semantic web. The performance of the hybrid ontology approach is measured using improved precision, recall and f-measure values. © 2015 The Authors.
Prabaharan M.,Hindustan University
International Journal of Biological Macromolecules | Year: 2015
Nanoparticles (NPs) have immense potential as drug-delivery carriers for cancer therapy due to their unique physicochemical properties. These particles can improve the pharmacological and therapeutic properties of the anti-cancer drugs by controlling release rates and targeted delivery process, which eliminate the limitations of conventional anti-cancer treatment methods. In recent years, chitosan-based NPs are emerging as one of the most promising delivery vehicles for cancer chemotherapy and diagnosis due to their unique characteristics such as biodegradability, biocompatibility, remarkable cell membrane penetrability, high drug-carrying capacities, pH-dependent therapeutic unloading, ability to have a multi-functionality and prolonged circulating time. This article reviews the recent developments on the preparation, properties and tumor-targeted drug-delivery applications of NPs based on chitosan and its derivatives. © 2014 Elsevier B.V.
Kamalakkannan K.,Hindustan University
SAE Technical Papers | Year: 2013
A semi-active suspension system (SASS) uses a damper whose damping rates can be varied automatically, by the influence of an electromagnet, in real-time according to the continuously changing road conditions. The method by which the damper is controlled is one of the crucial factors that ultimately determine the success or failure of it. In order to achieve success; the rear suspension damper is controlled, based on the inputs from sensors placed at front part of a vehicle, using H Skyhook Input Based control. The test vehicle is an All Terrain Vehicle (ATV) used in the standard of BAJASAE. This study includes a suspension system comprising of two controllable magneto-rheological dampers, associated sensors and controller. This paper reports the simulation result and performance of input based control of SASS fitted in a full car model. Copyright © 2013 SAE International.
Karthikeyan S.,Indira Institute of Engineering and Technology |
Ravikumar Solomon G.,Hindustan University |
Kumaresan V.,Anna University |
Velraj R.,Anna University
Energy Conversion and Management | Year: 2014
The focus of the present work is to perform parametric studies on the performance of a packed bed storage unit filled with phase change material (PCM) encapsulated spherical containers, suitable for low temperature solar air heating applications. A parametric analysis was carried out using the validated enthalpy based numerical model that considers the thermal gradient inside the PCM container. The results of simulation analysis showed that the size of the PCM ball, fluid inlet temperature and the mass flow rate of the heat transfer fluid (HTF) influenced respectively the heat transfer area in the packed bed, temperature difference between the HTF and PCM and the surface convective heat transfer coefficient between the HTF and PCM balls. The poor thermal conductivity of the PCM has only negligible effect on heat transfer due to high surface convective resistance provided by the air. The influence of various parameters for the selected range of values were analyzed using the charging time, instantaneous heat stored and cumulative heat stored during the charging process. © 2013 Elsevier Ltd. All rights reserved.
Jain V.,Defence Institute of Physiology and Allied science DIPAS |
Baitharu I.,Defence Institute of Physiology and Allied science DIPAS |
Prasad D.,Defence Institute of Physiology and Allied science DIPAS |
Ilavazhagan G.,Hindustan University
PLoS ONE | Year: 2013
Adverse environmental conditions such as hypobaric hypoxia (HH) cause memory impairment by affecting cellular machinery leading to neurodegeneration. Providing enriched environment (EE) is found to be beneficial for curing several neurodegenerative disorders. The protective role of EE in preventing HH induced neuronal death has been reported previously but the involved mechanism is still not clearly understood. The present study is an attempt to verify the impact of EE on spatial memory during HH and also to explore the possible role of neurotrophin in EE mediated neuroprotection. Signaling mechanism involved in neuroprotection was also explored. Male Sprague Dawley rats were simulated to HH condition in an Animal Decompression Chamber at an altitude of 25000 feet in standard and enriched cages for 7 days. Spatial memory was assessed through Morris Water Maze. Role of different neurotrophins was explored by gene silencing and inhibitors for their respective receptors. Further, using different blockers signaling pathway was also explored. Finding of the present study suggested that EE prevents HH mediated memory impairment and neurodegeneration. Also brain-derived neurotrophic factor (BDNF) plays a major role in EE mediated neuroprotection and it effectively prevented neurodegeneration by activating PI3K/AKT pathway resulting in GSK3β inactivation which further inhibits apoptosis. Moreover GSK3β phosphorylation and hence its inactivation upregulates CREB phosphorylation which may also accounts for activation of survival machinery in cells and provides neuroprotection. From these observations it can be postulated that EE has a therapeutic potential in amelioration of HH induced memory impairment and neurodegeneration. Hence it may be used as a non invasive and non pharmacological intervention against various neurological disorders. © 2013 Jain et al.
Sathyamurthy R.,Hindustan University |
El-Agouz S.A.,Tanta University |
Dharmaraj V.,Veltech Multitech Dr Rangarajan Dr Sakunthala Engineering College
Desalination | Year: 2015
In this paper, a new model portable solar still is designed, fabricated and tested in the summer conditions of Chennai climatic condition. The phase change material is used in order to divide a single slope portable solar still into evaporating and condensing chambers. The result shows that a maximum efficiency of 14% of the solar still with phase change material is achievable. The accumulated yield and obtained with PCM is 52% more efficient than accumulated yield obtained without PCM. The still continues to produce fresh water after the sunset. More than 34% of total water production is pertaining to this time. © 2015 Elsevier B.V.
Seralathan S.,Hindustan University |
Roy Chowdhury D.G.,Hindustan University
Procedia Engineering | Year: 2013
Efficient, compact centrifugal compressors with higher pressure ratios along with adequate surge margins are required for the future. Achieving these necessitates development of newer non-conventional diffuser designs and rotating vaneless diffusers is one such concept. One method of reducing the shear losses on the stationary vaneless diffuser sidewalls, with probable improved efficiency and flow range of low-to-medium specific speed stages, is the use of a "rotating diffuser". A particular type of rotating vaneless diffuser is forced rotating vaneless diffuser, in which the rotational speed equals that of the impeller and the rotating vaneless diffuser is integral with the centrifugal impeller which is created by extending the impeller disks beyond the blades. In the present paper, the effect of extended shroud by 10% with impeller exit diameter are analysed on flow diffusion and performance and compared with stationary vaneless diffuser. The higher static pressure rise with reduced losses and increased efficiency is achieved by shroud extension. © 2013 The Authors. Published by Elsevier Ltd.