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Mittal A.,Hind Institute of Medical science | Kumar S.,Lady Hardinge Medical College
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

Prospective and interventional. We studied the pH of external auditory canal (EAC) in normal individuals and patients with acute otitis externa (AOE), its variation with change of temperature and humidity, different symptoms and number of symptoms at presentation (Day 0) and various stages of treatment in 100 normal ears and forearms and 50 ears having AOE. The mean pH of normal EAC was 3.950 ± 1.199 while that of forearm was 4.775 ± 0.910. There was increase in the number of patients with increase in relative humidity, however, the change in the pH of EAC was statistically not significant (p > 0.05). Significant fall in pH was observed at 1 and 2 weeks of treatment. The normal EAC pH is relatively more acidic as compared to that of forearm skin and it became more alkaline in cases of AOE with reversion back to acidic pH after treatment. Acidification of the EAC is the only treatment required in most cases. No significant change in pH of ears was observed with changes of temperatures and humidity. © 2013 Association of Otolaryngologists of India. Source


Khare V.,Hind Institute of Medical science
BMJ case reports | Year: 2013

An 85-year-old man was admitted to the medical intensive care unit with a 10-day history of severe breathlessness, fever and cough. The patient was known to have chronic obstructive pulmonary disease and had been receiving corticosteroids in the preceding 18 months. He had been treated for tuberculosis 2.5 years previously. On examination he was febrile, tachycardic with a respiratory rate of 46/min. Auscultation revealed bilateral crepitation's and wheeze. Chest radiograph revealed patchy infiltrates on right lung. The patient developed respiratory depression and was mechanically ventilated. His sputum and endotracheal aspirates revealed Nocardia brasiliensis on culture which was found to be co-trimoxazole resistant. Once this became known imipenem was substituted for co-trimoxazole but unfortunately condition of the patient did not improve and he died following a cardiac arrest. Source


Gupta S.K.,Hind Institute of Medical science
International Journal of Dermatology | Year: 2015

Leprosy is a chronic granulomatous inflammation primarily of the peripheral nervous system, skin, and reticuloendothelial system caused by Mycobacterium leprae. It presents clinically as an erythematous or hypopigmented anesthetic patch and a thickened and/or tender cutaneous nerve trunk. Leprosy is also called Hansen disease. Leprosy is a great imitator of other skin diseases, and it can present with different morphological lesions, which is why an expert eye is needed to diagnose it. One of the important clinical presentations of leprosy is histoid leprosy, which is very difficult to diagnose due to different clinical and histopathological findings that mimic, e.g., a fibromatous disorder. Histoid leprosy is a very rare clinicopathological variant of leprosy. It is clinically characterized by skin-colored, soft, succulent nodules, and plaques on apparently normal skin and histologically by a dense bundle of histiocytes arranged in storiform. Though histoid leprosy is a very rare type of leprosy, the higher load of lepra bacilli in these cases makes it a concern as a reservoir for leprosy. © 2015 International Society of Dermatology. Source


Goel R.K.,Hind Institute of Medical science | Bhati Y.,Vardhman Mahavir Medical College and Safderjung Hospital | Dutt H.K.,Veer Chandra Singh Garhwali Government Medical science and Research Institute | Chopra V.S.,Santosh Medical College and Hospital
Journal of Applied Pharmaceutical Science | Year: 2013

The study was done to find out the current prescribing pattern in this tertiary care teaching hospital in Ghaziabad. The study was carried out at Santosh Medical College and Hospital over a period of 3 months. A total of 500 prescriptions were collected and analyzed. Total number of drugs prescribed was 1450 out of which 564 drugs were prescribed by generic names. Average number of drugs was 2.9. 327 drugs were fixed dose combinations while only 595 were from essential drug list. The mean number of drugs per prescription should be as low as possible otherwise there is increase risk of drug interaction, bacterial resistance, non-compliance and increase in cost The prescribing practices are more of irrational types like polypharmacy, use of vitamins and injections, less number of drugs by generic names and lesser drugs from Essential Drug List. There is an urgent need for some interventions to improve the situation. © 2013 Goel RK et al. Source


Thakur N.,Hind Institute of Medical science | Batra P.,University of Delhi | Gupta P.,University of Delhi
Indian Pediatrics | Year: 2016

Noise, a modern day curse of advancing infrastructure and technology, has emerged as an important public health problem. Exposure to noise during pregnancy may result in high-frequency hearing loss in newborns, growth retardation, cochlear damage, prematurity and birth defects. Newborns exposed to sound above 45 decibels may experience increase in blood pressure, heart rate, respiratory rate; decreased oxygen saturation; and increased caloric consumption. Noise exposure in older children may result in learning disabilities, attention difficulties, insulin resistance, hypertension, stress ulcers and cardiovascular diseases. Sudden exposure to loud noise can lead to rupture of eardrum. The damaging effects of noise pollution are more noticeable in large metropolitan cities, the hubs of urban settlements and industrial growth. Another concern is noise pollution inside the hospitals (particularly intensive care areas) that can lead to serious health consequences both for caregivers and for children. The issue needs to be addressed by both researchers and policy makers on an urgent basis. © 2016, Indian Academy of Pediatrics. Source

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