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Thakur N.,Hind Institute of Medical science | Rai N.,Hind Institute of Medical science
Journal of Tropical Pediatrics | Year: 2016

Eosinophilia is very common among rural poulation in Barabanki and neighbouring districts with no access to hygienic mode of stool disposition. Significant proportions of these children are suffering from anemia, undernutrition, anorexia, pain abdomen, cough and hence long term morbidity. This adds to the DALY of a developing country like India. All these chronic problems are preventable and treatable with simple corrective steps of which the most important ones are access to safe drinking water and toilet. The present study was conducted to study clinical and laboratory profile of patients with eosinophilia and to identify possible causes. © The Author 2016. Published by Oxford University Press.


Ramesh Babu C.S.,P.A. College | Lalwani R.,A.I.I.M.S. | Kumar I.,Hind Institute of Medical science
Journal of Clinical and Diagnostic Research | Year: 2014

Anomalies of the inferior vena cava (IVC) are uncommon and most of them remain asymptomatic. Though rare, anomalies of IVC can lead to severe hemorrhagic complications especially during aortoiliac surgery. Prior knowledge of these variations facilitates proper interpretation of radiological images and safe performance of interventional procedures and surgeries. During routine anatomical dissection of abdomen in a female cadaver we observed the presence of right sided duplication of inferior vena cava. Both IVCs were present on the right side of abdominal aorta, one ventral and the other more dorsal in position and named ventral right IVC and dorsal right IVC. The ventrally and medially placed IVC, which appeared to be the main IVC was formed by the union of two common iliac veins in front of the right common iliac artery (Preaortic iliac confluence -"Marsupial Cava"). The right external iliac vein continued as the more dorsally and laterally placed dorsal right IVC. The right internal iliac vein after receiving a transverse anastomotic vein from the external iliac continued as the right common iliac vein. This transverse anastomosis was present behind the right common iliac artery. The narrower dorsal right IVC joined the wider ventral right IVC just below the level of renal veins to form a single IVC. The abdominal aorta presented a convexity to the left.


Goel R.K.,Hind Institute of Medical science | Bhati Y.,Vardhman Mahavir Medical College and Safderjung Hospital | Dutt H.K.,Veer Chandra Singh Garhwali Government Medical Science and Research Institute | Chopra V.S.,Santosh Medical College and Hospital
Journal of Applied Pharmaceutical Science | Year: 2013

The study was done to find out the current prescribing pattern in this tertiary care teaching hospital in Ghaziabad. The study was carried out at Santosh Medical College and Hospital over a period of 3 months. A total of 500 prescriptions were collected and analyzed. Total number of drugs prescribed was 1450 out of which 564 drugs were prescribed by generic names. Average number of drugs was 2.9. 327 drugs were fixed dose combinations while only 595 were from essential drug list. The mean number of drugs per prescription should be as low as possible otherwise there is increase risk of drug interaction, bacterial resistance, non-compliance and increase in cost The prescribing practices are more of irrational types like polypharmacy, use of vitamins and injections, less number of drugs by generic names and lesser drugs from Essential Drug List. There is an urgent need for some interventions to improve the situation. © 2013 Goel RK et al.


Khare V.,Hind Institute of Medical science
BMJ case reports | Year: 2013

An 85-year-old man was admitted to the medical intensive care unit with a 10-day history of severe breathlessness, fever and cough. The patient was known to have chronic obstructive pulmonary disease and had been receiving corticosteroids in the preceding 18 months. He had been treated for tuberculosis 2.5 years previously. On examination he was febrile, tachycardic with a respiratory rate of 46/min. Auscultation revealed bilateral crepitation's and wheeze. Chest radiograph revealed patchy infiltrates on right lung. The patient developed respiratory depression and was mechanically ventilated. His sputum and endotracheal aspirates revealed Nocardia brasiliensis on culture which was found to be co-trimoxazole resistant. Once this became known imipenem was substituted for co-trimoxazole but unfortunately condition of the patient did not improve and he died following a cardiac arrest.


Ahuja R.,Hind Institute of Medical science | Rajpurohit A.C.,Hind Institute of Medical science
Indian Journal of Community Health | Year: 2014

Background: There is evidence of inequalities in immunization in India, despite the fact that childhood immunization has been an important part of maternal and child health services since the 1940s [1]. Objective: To evaluate the gender inequality in the missed opportunity for immunization in pre-school children in the rural population of Barabanki, Uttar Pradesh, India. Methods: This was a cross-sectional study conducted in the rural areas of Barabanki district among the children of 1-2 years of age. The information was collected on pre-designed questionnaire. A total of 15 villages were covered. A door to door survey was conducted in all the villages. There was 6% non-response due unavailability of mother/father of children. A total of 447 children were included in the study. Results: Out of the total children, 50.6% (226/447) were males and 49.4% (221/447) were females. Overall, 49.7% were fully immunized and 20.4% partially immunized. However, 5.8% were having contraindication for immunization. The percentage of fully immunized children was higher among males (54.4%) compared with females (44.8%). However, the percentage of partially immunized was found to be higher among females (21.3%) than males (19.5%). The percentage of contraindication was similar among both male and female children. Conclusion: Missed opportunity for immunization can be brought down by creating awareness periodically once in 2 or 3 months for immunization among health personnel. © Indian Association of Preventive and Social Medicine. All rights reserved.


Mittal A.,Hind Institute of Medical science | Mittal A.,Shekhar Hospital | Kumar S.,Lady Hardinge Medical College
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

Prospective and interventional. We studied the pH of external auditory canal (EAC) in normal individuals and patients with acute otitis externa (AOE), its variation with change of temperature and humidity, different symptoms and number of symptoms at presentation (Day 0) and various stages of treatment in 100 normal ears and forearms and 50 ears having AOE. The mean pH of normal EAC was 3.950 ± 1.199 while that of forearm was 4.775 ± 0.910. There was increase in the number of patients with increase in relative humidity, however, the change in the pH of EAC was statistically not significant (p > 0.05). Significant fall in pH was observed at 1 and 2 weeks of treatment. The normal EAC pH is relatively more acidic as compared to that of forearm skin and it became more alkaline in cases of AOE with reversion back to acidic pH after treatment. Acidification of the EAC is the only treatment required in most cases. No significant change in pH of ears was observed with changes of temperatures and humidity. © 2013 Association of Otolaryngologists of India.


Gupta S.,Hind Institute of Medical science | Gupta V.,Hind Institute of Medical science
Indian Journal of Dermatology | Year: 2015

Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprising of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual to develop two different types of tumor, benign and malignant, to arise simultaneously within a single sebaceus nevus. Here in, we report a case of a 27-year-old male with two neoplastic proliferations including a syringocystadenoma papilliferum a benign tumor and basal cell carcinoma a malignant tumor arising in a long-standing nevus sebaceus on the face. Neoplastic changes are common in nevus sebaceous present on scalp but our case is unique due to the presence of two different types of neoplasm in a nevus sebaceous which was present on face. © 2015 Indian Journal of Dermatology | Published by Wolters Kluwer - Medknow.


Upadhyaya P.,Mahatma Gandhi Medical College | Seth V.,Hind Institute of Medical science | Moghe V.V.,Mahatma Gandhi Medical College | Sharma M.,Mahatma Gandhi Medical College | Ahmed M.,Mahatma Gandhi Medical College
Therapeutics and Clinical Risk Management | Year: 2012

Introduction: Poor reporting of adverse drug reactions (ADRs) by doctors is a major hindrance to successful pharmacovigilance. The present study was designed to assess first-year residents' knowledge of ADR reporting. Methods: First-year postgraduate doctors at a private medical college completed a structured questionnaire. The responses were analyzed by nonparametric methods. Results: All doctors were aware of the term "adverse drug reactions." Fifty percent of the doctors reported being taught about ADR reporting during their undergraduate teaching, and 50% had witnessed ADRs in their internship training. Ten percent of patients suffering an ADR observed and reported by doctors required prolonged hospitalization for treatment as a result. Only 40% of interns reported the ADRs that they observed, while 60% did not report them. Twenty-eight percent reported ADRs to the head of the department, 8% to an ADR monitoring committee, and 4% to the pharmacovigilance center. Eighty-six percent of the doctors surveyed felt that a good knowledge of undergraduate clinical pharmacology therapeutics would have improved the level of ADR reporting. Conclusion: The knowledge of first-year doctors regarding ADR reporting is quite poor. There is a dire need to incorporate ADR reporting into undergraduate teaching, and to reinforce this during internships and periodically thereafter. © 2012 Upadhyaya et al, publisher and licensee Dove Medical Press Ltd.


Thakur N.,Hind Institute of Medical science | Batra P.,University of Delhi | Gupta P.,University of Delhi
Indian Pediatrics | Year: 2016

Noise, a modern day curse of advancing infrastructure and technology, has emerged as an important public health problem. Exposure to noise during pregnancy may result in high-frequency hearing loss in newborns, growth retardation, cochlear damage, prematurity and birth defects. Newborns exposed to sound above 45 decibels may experience increase in blood pressure, heart rate, respiratory rate; decreased oxygen saturation; and increased caloric consumption. Noise exposure in older children may result in learning disabilities, attention difficulties, insulin resistance, hypertension, stress ulcers and cardiovascular diseases. Sudden exposure to loud noise can lead to rupture of eardrum. The damaging effects of noise pollution are more noticeable in large metropolitan cities, the hubs of urban settlements and industrial growth. Another concern is noise pollution inside the hospitals (particularly intensive care areas) that can lead to serious health consequences both for caregivers and for children. The issue needs to be addressed by both researchers and policy makers on an urgent basis. © 2016, Indian Academy of Pediatrics.


Gupta S.K.,Hind Institute of Medical science
International Journal of Dermatology | Year: 2015

Leprosy is a chronic granulomatous inflammation primarily of the peripheral nervous system, skin, and reticuloendothelial system caused by Mycobacterium leprae. It presents clinically as an erythematous or hypopigmented anesthetic patch and a thickened and/or tender cutaneous nerve trunk. Leprosy is also called Hansen disease. Leprosy is a great imitator of other skin diseases, and it can present with different morphological lesions, which is why an expert eye is needed to diagnose it. One of the important clinical presentations of leprosy is histoid leprosy, which is very difficult to diagnose due to different clinical and histopathological findings that mimic, e.g., a fibromatous disorder. Histoid leprosy is a very rare clinicopathological variant of leprosy. It is clinically characterized by skin-colored, soft, succulent nodules, and plaques on apparently normal skin and histologically by a dense bundle of histiocytes arranged in storiform. Though histoid leprosy is a very rare type of leprosy, the higher load of lepra bacilli in these cases makes it a concern as a reservoir for leprosy. © 2015 International Society of Dermatology.

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