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Sharma R.D.,Himachal Institute of Dental science
Indian journal of dental research : official publication of Indian Society for Dental Research | Year: 2011

Recent advances in resin adhesives and restorative materials, as well as an increased demand for esthetics, have lead to the introduction of newer resin-based composites like nanocomposites and light-curing units like light emitting diodes (LEDs). The present study was conducted to evaluate the effect of conventional quartz tungsten halogen (QTH) curing unit and blue LED on marginal adaptation of microhybrid composite (Filtek Z250) and nanocomposite (Filtek Z350) resins. Eighty Class V cavities were prepared on, extracted human premolars and were divided into four groups of 20 each. The four groups were designed according to the restorative resin and light cure unit used microhybrid/QTH, nanocomposites/QTH, microhybrid/LED and nanocomposites/LED. After thermocycling and immersion in 2% Basic Fuschin dye solution, the teeth were sectioned and dye penetration was observed under a stereomicroscope at 20X magnification. Statistical Analysis: All the samples were scored and results were analyzed using the "Kruskal Wallis and Mann Whitney tests" with "Wilcoxone correction." The results revealed least microleakage in microhybrid composites exposed to QTH and maximum in nanocomposites exposed to LED. Conclusion: Microhybrid composites exhibited lesser microleakage than nanocomposite resins.

Batra R.,Himachal Institute of Dental science
Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology | Year: 2012

Failures in the normal course of embryonic development of the neural tube may give rise to a great variety of defects as the head and neck region develops. Such abnormalities may be manifested in the form of choristomas. The term choristoma applies to a cohesive tumor like mass consisting of normal cells in an abnormal location. Because of their benign tumor like growth and also their developmental pathogenesis, these need to be differentiated from neoplasms. Choristomas should also be distinguished from hamartomas which are tumor like malformations composed of a focal overgrowth of mature normal cells located where they are normally found. Since choristomas may arise from various tissues, mimicking various neoplasms, this review highlights the pathogenesis of different types of choristomas in the oral cavity. © 2011 Asian Association of Oral and Maxillofacial Surgeons.

Chauhan I.,Himachal Institute of Dental science | Beena V.T.,Government Dental College | Srinivas L.,Rajiv Gandhi Center for Biotechnology | Sathyan S.,Rajiv Gandhi Center for Biotechnology | Banerjee M.,Rajiv Gandhi Center for Biotechnology
Journal of Interferon and Cytokine Research | Year: 2013

Oral lichen planus (OLP) is a chronic mucocutaneous condition that affects the oral mucous membrane as well as skin. It is a chronic cell-mediated autoimmune condition where the T-cell-mediated immune response plays an important part in the pathogenesis by causing damage to basal keratinocytes in oral mucosa. Cytokine gene polymorphisms have an unquestionable role in the orchestration of the immune response, leading to different functional scenarios, which in turn influence the outcome of the disease establishment and evolution. The purpose of this study was to understand the role of these cytokine gene polymorphisms in the tumor necrosis factor-Alpha (TNF-α), interleukin-1β (IL-1β), and IL-6 genes with OLP in 101 individuals of Malayalam-speaking ethnicity from South India (Kerala). We further investigated the role of these polymorphisms in patients suffering from OLP with other comorbid factors. Genotyping was carried out by polymerase chain reaction-restriction fragment length polymorphism. The results demonstrate that the A allele in the TNF-α -308 polymorphism could play an important role in the susceptibility to OLP. IL-1β +3954 in OLP was associated with other comorbid factors in both allelic and genotypic combinations. However, when patients suffering from OLP were stratified to understand the involvement of other comorbid factors, we observed that the T and C alleles were independent risk factors for chronic periodontitits and diabetes mellitus. On the other hand, IL-6 -597 did not show any disease association with OLP in the study population. This study indicates that proinflammatory cytokines are an important factor in understanding the disease burden of OLP and their comorbid factors. © Copyright 2013, Mary Ann Liebert, Inc. 2013.

Verma G.,Himachal Institute of Dental science
Pain Research and Treatment | Year: 2013

Trigeminal neuralgia (TN) is a clinical condition characterized by paroxysmal attacks of severe and electric shock-like pain along the distribution of one or more branches of the trigeminal nerve. Various medicinal or surgical modalities have been employed in the past with variable success. Newer methods were tried in search of permanent cure or long-lasting pain relief. The purpose of this paper is to present the review of the literature regarding the use of botulinum toxin type-A (BTX-A) in the management of trigeminal neuralgia. © 2013 Gaurav Verma.

Kamal R.,Himachal Institute of Dental science | Dahiya P.,H.I.D.S
Journal of Natural Science, Biology and Medicine | Year: 2011

The nasolabial cyst is a rare nonodontogenic cyst originating in maxillofacial soft tissues. In the previous reports and literature, it is mentioned that nasolabial cyst clinical features of an asymptomatic swelling beneath the ala of nose and characteristic lip swelling are diagnostic. This is a case report of a 36-year-old male, who reported to our department with the chief complaint of swelling lateral to right ala of nose since 4 months. Characteristic lip swelling was missing. The reason for this unusual finding is not documented in the literature.

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