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Summersgill F.C.,High Street Partners | Kontoe S.,Imperial College London | Potts D.M.,Imperial College London
Computers and Geotechnics | Year: 2017

This study examines the use of nonlocal regularisation in a coupled consolidation problem of an excavated slope in a strain softening material. The nonlocal model reduces significantly the mesh dependency of cut slope analyses for a range of mesh layouts and element sizes in comparison to the conventional local approach. The nonlocal analyses are not entirely mesh independent, but the predicted response is much more consistent compared to the one predicted by local analyses. Additional Factor of Safety analyses show that for drained conditions the nonlocal regularisation eliminates the mesh dependence shown by the conventional local model. © 2016 The Authors


Parsons D.,High Street Partners | Goodhew S.,Nottingham Trent University | Fewkes A.,Nottingham Trent University | de Wilde P.,University of Plymouth
Urban Water Journal | Year: 2010

This work investigates the barriers that exist to deter the implementation of rainwater harvesting into new UK housing. A postal questionnaire was sent to a selection of large, medium and small house-builders distributed across the UK. Questions were asked concerning potential barriers to the inclusion of rainwater harvesting in homes separated into five sections;(1) institutional and regulatory gaps, (2) economic and financial constraints, (3) absence of incentives, (4) lack of information and technical knowledge, and (5) house-builder attitudes. The study concludes that although the knowledge of rainwater systems has increased these barriers are deterring house-builders from installing rainwater harvesting systems in new homes. It is further acknowledged that the implementation of rainwater harvesting will continue to be limited whilst these barriers remain and unless resolved, rainwater harvesting's potential to reduce the consumption of potable water in houses will continue to be limited. © 2010 Taylor & Francis.


Ousey J.C.,High Street Partners
Equine veterinary journal. Supplement | Year: 2012

Prostaglandins play an essential role during the perinatal period in the mare. Prostaglandin concentrations are low for the majority of pregnancy due to the regulatory action of progestagens on those enzymes responsible for metabolism of prostaglandins. Towards term, prostaglandin concentrations gradually increase, closely associated with upregulation of the fetal hypothalamo-pituitary-adrenal axis, stimulation of the prostaglandin synthesising enzyme PGHS-2 and changes in the ratio of progestagens and oestrogens. Recent evidence in the mare indicates that proinflammatory cytokines are key mediators of prostaglandin synthesis both at term parturition in healthy mares and at preterm parturition associated with placental infection. Prostaglandin concentrations rise substantially during active labour and decline after birth, associated with delivery of the placenta. During induced labour, prostaglandin concentrations are variable depending on the proximity to spontaneous parturition at term. Once the proinflammatory endocrine cascade is initiated, it is difficult to prevent active labour by administration of drugs that reduce prostaglandin concentrations in peripheral plasma. Further work is needed to establish the inter-relationships between prostaglandin production and other endocrine changes associated with labour at term and preterm in the mare.


Farmer N.,High Street Partners | Smith I.,High Street Partners
Advanced Composites in Construction 2011, ACIC 2011 - Proceedings of the 5th International Conference | Year: 2011

The paper describes a cross-sector collaborative project, part-funded by the Technology Strategy Board, to investigate node manufacture and joining for large 'all composite' truss structures and space frames (3D truss structures) based on 3D weave and 2D aligned fibre reinforcements - two areas that are considered most important in composite space frame technology. The specific objectives of this project were to:• develop baseline designs for 2D (aligned, chopped carbon) and 3D woven textile reinforced composite nodes • simulate infusion, cure and mechanical performance for the 3D weave reinforced nodes • manufacture nodes, based on carbon fibre and an advanced epoxy resin • develop automated 3D woven fabric and 2D aligned fibre reinforcement processes • develop joint design and modelling, for different sector requirements, based on three types of strut material, being aluminium, epoxy and vinyl ester composites • assess suitable structural health monitoring techniques and • determine suitable repair strategies for two different levels of damage. The Project Partners were drawn from the civil infrastructure, aeronautical, automotive, defence and composites sectors facilitating technology transfer across industries and embracing expertise drawn from academic establishments. The design, manufacture and testing of the nodes over the three year duration of the project are described and the application of this technology to footbridges over railways is examined.


Ramzan P.H.L.,High Street Partners | Palmer L.,High Street Partners
Veterinary Journal | Year: 2011

Musculoskeletal injury is the most common cause of lost training days in the young Thoroughbred horse in flat race training. To date, there has been little investigation of the regional patterns of injury frequently observed by clinicians in racehorse practice. The present study was conducted to determine incidence of musculoskeletal injuries in Thoroughbreds in training in Newmarket, United Kingdom. Veterinary records for all horses resident in three large (>100 horse) training yards were assessed for occurrence of significant musculoskeletal injury.A total of 248 injuries were recorded in 217 individual horses, from a total population of 616 individual horses; fractures of the tibia (20.7%) and proximal phalanx (14.5%) were the most common. Overall injury rates were similar between yards (23-26%/year), with seasonal patterns noted for some injury types. Incidence of certain injuries (P1, metacarpal/metatarsal condylar, pelvic fractures, and superficial digital flexor tendonitis) varied between yards. The majority of carpal, P1 fracture and SDF tendonitis cases were right-sided. © 2009 Elsevier Ltd.


Patent
High Street Partners | Date: 2012-06-06

A user interface to an application is used to manage a collection of data associated with a plurality of business management functions of a multi-national entity. The user interface includes a set of presentation objects, at least some of the presentation objects being operable to control a presentation of information within the user interface. Responsive to input selecting a first presentation object of the set, a first view of a subset of the collection of data associated with a first of the plurality of business management functions is visually rendered in a first region of the user interface.


PubMed | High Street Partners
Type: | Journal: Equine veterinary journal. Supplement | Year: 2012

Prostaglandins play an essential role during the perinatal period in the mare. Prostaglandin concentrations are low for the majority of pregnancy due to the regulatory action of progestagens on those enzymes responsible for metabolism of prostaglandins. Towards term, prostaglandin concentrations gradually increase, closely associated with upregulation of the fetal hypothalamo-pituitary-adrenal axis, stimulation of the prostaglandin synthesising enzyme PGHS-2 and changes in the ratio of progestagens and oestrogens. Recent evidence in the mare indicates that proinflammatory cytokines are key mediators of prostaglandin synthesis both at term parturition in healthy mares and at preterm parturition associated with placental infection. Prostaglandin concentrations rise substantially during active labour and decline after birth, associated with delivery of the placenta. During induced labour, prostaglandin concentrations are variable depending on the proximity to spontaneous parturition at term. Once the proinflammatory endocrine cascade is initiated, it is difficult to prevent active labour by administration of drugs that reduce prostaglandin concentrations in peripheral plasma. Further work is needed to establish the inter-relationships between prostaglandin production and other endocrine changes associated with labour at term and preterm in the mare.


News Article | December 16, 2016
Site: www.prweb.com

Globalization Partners, a global PEO and employer of record firm that helps companies expand internationally without setting up foreign branch offices, today announced that Debbie Millin will serve as the organization's chief operating officer, effective immediately. Millin joined Globalization Partners in June as senior director of systems and scalability. Thanks to her expertise and proven results driving executive-level expansion strategies, she has been instrumental in the company's rapid growth in the second half of 2016. Millin will continue to report directly to CEO Nicole Sahin. Millin brings more than 20 years of global experience to Globalization Partners. Prior to joining the company in June, she ran UpperLevel Solutions, a consulting firm she founded with the mission of helping startups manage the challenges that come with high growth and success. Previously, she was vice president of operations at High Street Partners (now Radius) where she played a key role in driving business operations. "Debbie is an incredible day-to-day resource for our entire team and has quickly become a central and exemplary addition to the health and growth of our organization," said Sahin. "I am confident that she will continue to thrive in the role of chief operating officer, pulling from her years of global and client relations experience to help us nimbly and efficiently run one of the fastest growing businesses in Boston." Globalization Partners addresses a major pain point for U.S. organizations looking to expand overseas by putting employees on its own payroll and therefore taking on all associated risk as it relates to human resources, payroll and compliance regulations. With a presence in more than 150 countries, Globalization Partners cuts the cost of international expansion by as much as 94 percent, reducing time to onboard a new employee from months to days and turning international payroll and HR management into a fast and easy process. "Even before joining Globalization Partners, I was incredibly impressed with the organization's work and the team's amazing and unique ability to help clients grow globally," said Millin. "I am more energized today than ever, and look forward to diving into my new role head first as we continue to grow and expand our business operations." Millin's appointment to chief operating officer comes on the heels of a tremendous growth year for Globalization Partners. In August, the company was ranked number six on the Inc. 500 list of fastest-growing companies in the U.S., reporting $17.7 million in 2015 revenue, an increase of 16,196 percent since its first year of business in 2012. It has also made several key hires in 2016, including the appointment of Dave Hughson as national director of business development in September, and the addition of several senior sales and business development representatives across the country. For more information, please visit http://www.globalization-partners.com. ABOUT GLOBALIZATION PARTNERS Founded with the goal of making it easy to hire employees in other countries while minimizing the legal, HR and tax red tape that companies typically encounter, Globalization Partners empowers companies to hire the most talented people in more than 150 countries without first incorporating in each country. Using tailored International PEO Services and our Global Employer of Record Platform, we minimize the risk of global expansion and enable fast entry into new markets. Less risk. More reward. Streamlined Global Employment.


PubMed | High Street Partners
Type: Journal Article | Journal: Equine veterinary journal | Year: 2013

Ultrasonographic (US) abnormalities of the suspensory ligament branch (SLB) have been poorly investigated but can have considerable impact on market value and career path when encountered in athletic horses. There is a need for determination of the prevalence and relationship to clinical injury of these US abnormalities in the Thoroughbred (TB) racehorse.To establish the prevalence of, and the repeatability of an US grading system for, subclinical US abnormalities of the forelimb SLB in a population of UK TB flat racehorses.Ultrasonographic assessment of the forelimb SLBs of 60 TB racehorses free from history and clinical indication of SLB desmopathy in a single UK training yard was performed. Images were viewed independently by 2 blinded observers and graded for US abnormality. Interobserver agreement was assessed using Cohens kappa statistic with 95% confidence intervals (95% CI).Prevalence of horses with subclinical US abnormality of the forelimb SLB of moderate severity was 6.7%. Medial branches were overrepresented. Inter observer agreement was substantial for US grade (kappa = 0.743; 95% CI 0.652-0.834) and almost perfect for appearance of sesamoid bone at ligament insertion (kappa = 0.817; 95% CI 0.66-0.98).The study reveals that a proportion of TB racehorses in flat training free from history or clinical signs of SLB injury have US abnormalities that could negatively impact on market value and career path.Clinicians should be aware that US abnormalities of the SLB may not always be related to clinical desmopathy. Further longitudinal studies are required to determine whether such findings are predictive for future injury.

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