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Nijmegen, Netherlands

Jonker A.M.,Heyendaalseweg 135 | Borrmann A.,Heyendaalseweg 135 | Van Eck E.R.H.,Heyendaalseweg 135 | Van Delft F.L.,Heyendaalseweg 135 | And 2 more authors.
Advanced Materials

(Figure Presented) Strain-promoted oxidation-controlled cyclooctyne 1,2 quinone cycloaddition (SPOCQ) is a fast and activatable cross-linking strategy for hydrogel formation. Gelation is induced by oxidation, which is performed both chemically using sodium periodate and enzymatically using mushroom tyrosinase. Due to the fast reaction kinetics, SPOCQ-formed hydrogels can be functionalized in one-pot with an azido-containing moiety using SPAAC cross-linking. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA. Source

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