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Przybylik-Mazurek E.,Jagiellonian University | Zagrodzki P.,Jagiellonian University | Zagrodzki P.,Henryk Niewodniczanski Institute of Nuclear Physics | Kuzniarz-Rymarz S.,Jagiellonian University | Hubalewska-Dydejczyk A.,Jagiellonian University
Biological Trace Element Research | Year: 2011

The trace elements studied in this work (Se, Cu, Zn) are the essential constituents or cofactors required to activate numerous enzymes and proteins, playing crucial role in various physiological processes. The disturbed levels of abovementioned elements may adversely affect the endocrine system, resulting in various thyroid disorders among other upsets. The aim of this study was to investigate possible associations between them and parameters of redox balance, thyroid function indices as well as clinical records (duration of disease and therapy, lag time between thyroid surgery and this study examination, LT4 dosage) in patients with different thyroid disorders, including malignant diseases of the gland. In the group of patients with papillary carcinoma, we found a statistically significant higher Cu concentration compared with controls and patients with Hashimoto disease. In the same groups, the parameter of Zn/Cu ratio demonstrated reciprocally arranged statistically significant differences. For the group of papillary cancer patients, there was a negative correlation between lag time since thyroid operation and GPX3 activity. Our data support hypothesis of indirect involvement of Zn and Cu in thyroid regulation. For selenium, lack of simple correlation between its serum level and thyroid indices implies the need for further research on other selenium status parameters more adequately depicting changes in endocrine system. © 2010 Springer Science+Business Media, LLC. Source

La Rosa J.J.,IAEA Marine Environment Laboratory MEL | La Rosa J.J.,U.S. National Institute of Standards and Technology | Mietelski J.W.,Henryk Niewodniczanski Institute of Nuclear Physics | Wyse E.,IAEA Marine Environment Laboratory MEL | Wyse E.,Advanced Technologies and Laboratories International
Journal of Radioanalytical and Nuclear Chemistry | Year: 2010

Described are results and the procedure for a pilot study on 237Np content in forest litter samples from Poland in relation to their plutonium activity. Neptunium was determined by inductively coupled plasma mass spectrometry (ICP-MS) and Pu by alpha spectrometry. Two samples originated from a location with pure global fallout and two others from a place with about 65% of the plutonium from Chernobyl. Plutonium activities were determined twice: at Krakow and in Monaco. The two results were consistent and 239 + 240Pu activities ranged from about 1 to about 7 Bq/kg dry weight (dw). The chemical recovery for Np was between 27 and 89%. Results for 237Np activity concentrations were between 0.099 ± 0.005 and 2.21 ± 0.076 mBq/kg dw. Observed activity ratios were lower than expected and could be explained by fractionation of Np against Pu in forest litter. © 2009 Akadémiai Kiadó, Budapest, Hungary. Source

Cerkaski M.,Henryk Niewodniczanski Institute of Nuclear Physics | Nazmitdinov R.G.,University of the Balearic Islands | Nazmitdinov R.G.,Joint Institute for Nuclear Research
Journal of Physics: Conference Series | Year: 2014

We discuss a novel theoretical approach which explains the self-organization of charged particles in a disk geometry. It allows to calculate readily equilibrium configurations for n ≤ 400 with a remarkable accuracy, when compared with the molecular dynamics calculations. © Published under licence by IOP Publishing Ltd. Source

Szybinski Z.,Jagiellonian University | Walas S.,Jagiellonian University | Zagrodzki P.,Henryk Niewodniczanski Institute of Nuclear Physics | Sokolowski G.,Jagiellonian University | And 2 more authors.
Biological Trace Element Research | Year: 2010

The purpose of this work was to determine trace element levels in urine and evaluate possible associations between urinary iodine concentration (UIC), other trace elements (Cr, Cu, Fe, Mn, Na, Se, Zn), toxic elements (Cd, Pb), anthropometrical measures (body weight and height), glycemic indices (serum insulin and glucose), and several parameters related to thyroid function (thyroid stimulating hormone, free thyroxine, antithyroid peroxidase antibodies, thyroid volume, and thyroid echogenicity) in pregnant women. One hundred sixty-nine participants were recruited. The whole study group, originating from Krakow region, comprised three subgroups belonging to three trimesters: I trimester (n = 28), II trimester (n = 83), and III trimester (n = 58). Trace elements were determined using inductively coupled plasma mass/(atomic emission) spectrometry. Partial least square model was used to reveal correlation structure between parameters investigated, as well as a possible causal relationship between dependent parameters and potentially explanatory parameters. Results obtained for trace and toxic elements in urine were comparable with results of other authors, although the study group was not homogenous. We confirmed (1) low iodine excretion in pregnant women, (2) the existence of statistically significant correlation between UIC and urinary selenium, and (3) lack of correlation between latter parameter and typical indices of thyroid function. Urinary selenium correlated with other urinary trace elements, but physiological significance of this finding remains uncertain. The fact that a large number of pregnant women fail to meet dietary recommendations for iodine is the major reason for concern. © 2010 Springer Science+Business Media, LLC. Source

Czerski P.,Henryk Niewodniczanski Institute of Nuclear Physics
International Journal of Modern Physics A | Year: 2011

Net proton rapidity distributions are calculated, reproduce very well data obtained at AGS, SPS, RHIC and predict results for the LHC experiment. Presence of non-ideal plasma effects due to strongly coupled plasma in the early stage of relativistic heavy-ion collisions is investigated in the framework of non-conventional statistical mechanics. © 2011 World Scientific Publishing Company. Source

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