Peng Zhang M.M.,Henan UniversityHenan |
Jifeng Li M.M.,Henan UniversityHenan |
Xiao Wang M.M.,Henan UniversityHenan
International Journal of Surgery | Year: 2017
Objective To compare the efficacy and safety of the combined application of both intravenous and topical tranexamic acid versus the single use of either application in patients with total knee and hip arthroplasty. Methods Potentially relevant studies were identified from electronic databases including Medline, PubMed, Embase, ScienceDirect and the Cochrane Library. Patients undergoing primary total knee and hip arthroplasty were included in our studies, with an experimental group that received combined intravenous and topical application of tranexamic acid and a control group that received a single application of tranexamic acid or normal saline. The primary outcomes were total blood loss, hemoglobin decline and transfusion requirements. The secondary outcomes were length of stay, operation time and tranexamic acid-related adverse effects, such as superficial infection, deep vein thrombosis or pulmonary embolism. Modified Jadad scores were used to assess the quality of the included randomized controlled trials (RCTs). The data was pooled using RevMan 5.3. After testing for heterogeneity across studies, the data were aggregated using random-effects modeling when appropriate. We have registered the trial at http://www.researchregistry.com. Results Six RCTs that included 704 patients met the inclusion criteria. The present meta-analysis indicated significant differences existed in the total blood loss (MD = −134.65, 95% CI: −191.66 to −77.64, P < 0.0001), postoperative hemoglobin level (MD = 0.74, 95% CI: 0.39 to 1.10, P < 0.0001), drainage volume (MD = −40.19, 95% CI: −55.95 to −24.43, P < 0.00001) and transfusion rate (RD = −0.07, 95% CI: −0.11 to −0.03, P = 0.0004) between groups. Conclusion Combined administration of tranexamic acid in total knee and hip arthroplasty was associated with significantly reduced total blood loss, postoperative hemoglobin decline, drainage volume, and transfusion requirements. Based on the limitations of current meta-analysis, well-designed, high-quality RCTs with long-term follow-up are still required. © 2017 IJS Publishing Group Ltd
Wang X.,Henan UniversityHenan |
Wang X.,Henan University |
Lv X.,Henan UniversityHenan |
Zhang B.,Henan UniversityHenan |
And 2 more authors.
Journal of Chemical Engineering of Japan | Year: 2015
Polyaspartic acid/diethylenetriamine (PASP/DETA) graft copolymer was synthesized by urea, maleic anhydride and diethylenetriamine and its performance was evaluated by the static scale inhibition method. Due to the intramolecular hydrogen bonds of the side chains, the seven-member heterocycles were formed in graft copolymers. The results showed that the graft copolymers possessed improved scale inhibition performance against Ca3(PO4)2compared with PASP. The scale inhibition efficiency was close to 100% against Ca3(PO4)2and CaCO3, when the concentration of PASP/DETA was 15 mg/L and 6 mg/L, respectively. Meanwhile, its scale inhibition performance was studied in different solution pH and temperature. The CaCO3 and Ca3(PO4)2 crystal turned into irregular shapes with the introduction of PASP/DETA in the solution, which was observed by scanning electron microscopy. © 2015 The Society of Chemical Engineers, Japan.
Li H.Q.,Henan UniversityHenan |
Si L.X.,Henan UniversityHenan
Material Science and Environmental Engineering - Proceedings of the 3rd annual 2015 International Conference on Material Science and Environmental Engineering, ICMSEE 2015 | Year: 2016
Kaifeng City, surrounded by sand, was greatly endangered by sandstorms especially in the spring because the northwest wind blew throughout the year in the Northern Song dynasty. For this purpose, some measures were taken to improve the environment, such as planting trees, sprinkling water on the streets, greening streets, cleaning ditches, and excavating lakes. These measures can serve as a reference for present-day urban environmental regulation. © 2016 Taylor and Francis Group, London.