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Han S.,Wenzhou Medical College | Ji S.,Henan Provincial Tumor Hospital | Guo S.,Wenzhou Medical College | Li W.,Wenzhou Medical College
Chinese-German Journal of Clinical Oncology | Year: 2010

Cloacogenic carcinoma is a rare tumor of rectum and anus, which originating from epithelium of the anal transition zone of embryonic residuals. We described the medical history of two patients with cloacogenic carcinoma of anal canal and reviewed of the Chinese literature (January 1994 to March 2009). In conclusion, cloacogenic carcinoma of anal canal can obtain good results with a abdominoperineal excision (APE). © Springer-Verlag Berlin Heidelberg 2010. Source


Xu J.-L.,Henan Provincial Peoples Hospital | Li Y.-L.,Henan Provincial Peoples Hospital | Lian J.-M.,Henan Provincial Peoples Hospital | Dou S.-W.,Henan Provincial Peoples Hospital | And 3 more authors.
Neuroradiology | Year: 2010

Introduction: This study aims to evaluate the differentiated effectiveness of MR diffusion tensor imaging (DTI) to postoperative recurrent glioma and radiation injury. Methods: Conventional MRI and DTI examination were performed using Siemens 3.0 T MR System for patients with new contrast-enhancing lesions at the site of treated tumor with postoperative radiotherapy. The region of interest was manually drawn on ADC and FA maps at contrast-enhancing lesion area, peri-lesion edema, and the contra-lateral normal white matter. Then ADC and FA values were measured and, the ADC ratio and FA ratio were calculated. Twenty patients with recurrent tumor and 15 with radiation injury were confirmed by histopathologic examination (23 patients) and clinical imaging follow-up (12 patients), respectively. The mean ADC ratio and FA ratio were compared between the two lesion types. Results: The mean ADC ratio at contrast-enhancing lesion area was significantly lower in patients with recurrent tumor (1.34∈±∈0.15) compared to that with radiation injury (1.62∈±∈0.17; P∈<∈0.01). The mean FA ratio at contrast-enhancing lesion area was significantly higher in patients with recurrent tumor (0.45∈±∈0.03) compared to that with radiation injury (0.32∈±∈0.03; P∈<∈0.01). Neither mean ADC ratio nor FA ratio in edema areas had statistical difference between the two groups. A recurrent tumor was suggested when either ADC ratio∈<1.65 or/and FA ratio >0.36 at contrast-enhancing lesion area according to the receiver operating characteristics curve analysis. Three patients with recurrent tumor and two with radiation injury were misclassified. Conclusion: DTI is a valuable method to distinguish postoperative recurrent glioma and radiation injury. © 2010 Springer-Verlag. Source


Wu S.-j.,Guangdong Provincial Hospital of Traditional Chinese Medicine | Liang K.-w.,Guangdong Provincial Hospital of Traditional Chinese Medicine | Wu Y.-b.,Guangdong Provincial Hospital of Traditional Chinese Medicine | Zhou J.,Henan Provincial Tumor Hospital | Tu S.-f.,Southern Medical University
Chinese Journal of Tissue Engineering Research | Year: 2012

BACKGROUND: At present, the method for the treatment of chronic graft versus host disease is not ideal due the adverse reactions, founding the traditional Chinese medicine for effective intervention and treatment of chronic graft versus host disease is one of the common focuses of attention for the transplant scholars. OBJECTIVE: To observe effect of Guifu rehmaniae bolus on preventing chronic graft versus host disease in major histocompatibilty complex halpo-identical bone marrow transplantation mice. METHODS: Transplantation models of major histocompatibilty complex halpo-identical hematopoietic stem cells transplantation mice were established by transplanting the hematopoietic stem cells of male Balb/cH-2d mice to female (Balb/c×C57BL/6) F1 H-2d/b (CB6F1) mice. After transplantation, 24 recipient mice were divided into two groups: Guifu rehmaniae bolus group and blank group, mice in the Guifu rehmaniae bolus group were lavaged from the first day after transplantation with 0.2 mL Guifu rehmaniae bolus liquid twice per day; mice in the blank group were lavaged with the same dose of normal saline and lasted for 100 days. RESULTS AND CONCLUSION: Five mice died in the Guifu rehmaniae bolus group, and all mice died in the blank group at 86 days after transplantation (P=0.004). The mice in the blank group depressed at 35 days after transplantation and the mice in the Guifu rehmaniae bolus group depressed at 45 days after transplantation, and the clinical score in the blank group was significantly higher than that in the Guifu rehmaniae bolus group (P < 0.05). Pathological observation showed that the mice with chronic graft versus host disease in Guifu rehmaniae bolus group mostly classified from 0 to 1 grade. Compared with blank group, the liver, skin and small intestine tissue of the mice in Guifu rehmaniae bolus group were improved. Guifu rehmaniae bolus can relieve symptoms of chronic graft versus host disease in major histocompatibilty complex halpo-identical bone marrow transplantation mice effectively and prolong their survival time, and improve histologic manifestations. Source


Zhao Y.Z.,Henan Provincial Tumor Hospital
Zhonghua yi xue za zhi | Year: 2011

To explore the effects of splenic flexure and sigmoid colon variation on anastomosis after left colectomy. The clinical data of 76 descending colon patients were collected retrospectively from March 2004 to April 2011 at our hospital. Statistical analysis was performed for the types of splenic flexure and sigmoid colon with regards to the choice of anastomosis. There were mesenteric type (n = 55), mobile type (n = 7) and adhesive type (n = 14) for splenic flexure. And among 61 regular types, 15 were of variable type for sigmoid colon variation. There was significant difference of anastomosis between the types of sigmoid colon variation [43 (78.2%) vs 5 (71.4%) vs 9 (64.3%), P > 0.05] while no significant difference existed between the types of splenic flexure [I type 56(91.8%) vs II type 1 (14.3%), III or IV type 0, P < 0.05]. A clinician should pay more attention to the types of sigmoid colon variation. And it helps to select the right approach of anastomosis after left colectomy. Source


Yang H.,Henan Provincial Tumor Hospital | Liu H.,Fudan University | Peng W.,Fudan University | Hua Y.,Fudan University
Journal of Computer Assisted Tomography | Year: 2012

OBJECTIVE: To evaluate the role of magnetic resonance imaging (MRI) in the detection of residual disease for patients after excisional biopsy of breast carcinoma, before re-excision. MATERIALS AND METHODS: We performed a retrospective review of 97 patients who underwent MRI soon after excisional biopsy of breast carcinoma with undeterminable margin status before further surgical intervention to determine the value of MRI in detecting residual disease. RESULTS: The positive predictive value was 50.0%. The negative predictive value was 78.9%. The MRI detected 54.5% of the residual disease for invasive ductal carcinoma and 100% for ductal carcinoma in situ. Positive predictive value and sensitivity for MRI conducted within 14 days of the original surgery were lower than those for MRI conducted after 14 days of the original surgery, being 31.6% and 46.2% versus 66.7% and 73.4%, respectively. The difference between the positive predictive value within 14 days versus after 14 days was statistically significant. CONCLUSION: Magnetic resonance imaging in detecting residual disease soon after excisional biopsy for breast carcinoma had a low positive predictive value and moderately high negative predictive value. Magnetic resonance imaging was more sensitive in detecting residual ductal carcinoma in situ than invasive ductal carcinoma. Magnetic resonance imaging conducted more than 14 days after the original biopsy had a significantly higher positive predictive value than MRI done within 14 days. © 2012 Lippincott Williams & Wilkins, Inc. Source

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