Henan Hospital of Traditional Chinese Medicine

Zhengzhou, China

Henan Hospital of Traditional Chinese Medicine

Zhengzhou, China
SEARCH FILTERS
Time filter
Source Type

Wang S.,Meridian | Wang S.,Shanghai University of Traditional Chinese Medicine | Lv J.,Shanghai JiaoTong University | Feng X.,Meridian | And 2 more authors.
Urology | Year: 2016

Objective To compare the efficacies of electrical pudendal nerve stimulation (EPNS) vs electromyogram biofeedback (BF)-assisted pelvic floor muscle training (PFMT) plus transvaginal electrical stimulation (TES) in treating female stress urinary incontinence (SUI) and to evaluate the posttreatment and long-term efficacies of EPNS for female SUI. Materials and Methods Forty-two female SUI patients were randomized into groups I and II, 21 in each group. The two groups were treated by EPNS and BF-assisted PFMT plus TES, respectively, for comparison of their effects. Group III (196 patients) were treated by EPNS for evaluation of its effects. To perform EPNS, long acupuncture needles were deeply inserted into four sacrococcygeal points and electrified to stimulate pudendal nerves. Outcome measures were stress test, 24-hour pad test, and a questionnaire to measure the severity of symptoms and quality of life in women with SUI. Results After 4 weeks of treatment, the questionnaire score was lower and the therapeutic effect was better in group I (questionnaire score 0 [0, 6] and a ≥ 50% symptom improvement rate of 85.7%, respectively) than in group II (questionnaire score 9 [5.5, 15.5] and a ≥ 50% symptom improvement rate of 28.6%) (both P <.01). In group III, complete resolution occurred in 94 cases (48.0%), with a ≥ 50% symptom improvement rate of 85.7%, after 20.3 ± 16.8 sessions of treatment. At the mean follow-up of 52.9 months, complete resolution occurred in 32 (47.1%) of the 68 patients in group III who attained ≥50% posttreatment improvement. Conclusion EPNS is more effective than BF-assisted PFMT plus TES in treating female SUI. It has good posttreatment and long-term effects on female SUI. © 2016 Elsevier Inc.


Li Y.,Hubei University | Li Y.,Henan Hospital of Traditional Chinese Medicine | Zhang X.,Henan Hospital of Traditional Chinese Medicine | Wang C.,Henan Hospital of Traditional Chinese Medicine | And 5 more authors.
Molecular Medicine Reports | Year: 2015

Pseudomonas aeruginosa continues to be a predominant cause of infections with high intrinsic resistance to antibiotics, resulting in treatment failure. P. aeruginosa is the leading cause of respiratory infections among cystic fibrosis (CF) patients. Resistance to carbapenem antibiotics among P. aeruginosa has been reported. Thus, this study was undertaken to characterize the metallo-β-lactamase (MBL) production of P. aeruginosa by phenotypic and genotypic methods. A total of 572 sputum samples were collected from cystic fibrosis patients along with the patient demographic details in a questionnaire. In total, 217 P. aeruginosa isolates were collected and an antibiogram revealed that 159 (73.3%) and 141 (64.9%) of these colonies exhibited resistance to imipenem and meropenem, respectively. Ceftazidime and tobramycin resistance were both identified in 112 (51.6%) isolates, and resistance to piperacillin.tazobactam, gatifloxacin and netilmicin was detected in 96 (44.2%) respective samples. A total of 62 (28.6%) respective samples were resistant to cefoperazone, cefepime and ceftriaxone. The least antibiotic resistance was shown to amikacin and ceftizoxime with 51 (23.5%) and 32 (14.7%) respective colonies resistant to the antibiotics. The minimum inhibitory concentration (MIC) for imipenem revealed a reduction in the MIC values. MBL screening by the zone enhancement method using ceftazidime plus EDTA discs demonstrated that 63 (56.25%) of the colonies were positive for MBL. A total of 53 (84.1%) samples expressed blaVIM and 48 (76.1%) expressed blaIMP genes, as detected by duplex polymerase chain reaction. In conclusion, carbapenem resistance is of great clinical concern in cystic fibrosis patients with P. aeruginosa infection. Therefore, mandatory regular screening and monitoring the resistance in P. aeruginosa among CF patients is required.


PubMed | Hubei University and Henan Hospital of Traditional Chinese Medicine
Type: Journal Article | Journal: Molecular medicine reports | Year: 2014

Pseudomonas aeruginosa continues to be a predominant cause of infections with high intrinsic resistance to antibiotics, resulting in treatment failure. P. aeruginosa is the leading cause of respiratory infections among cystic fibrosis (CF) patients. Resistance to carbapenem antibiotics among P. aeruginosa has been reported. Thus, this study was undertaken to characterize the metallo--lactamase (MBL) production of P. aeruginosa by phenotypic and genotypic methods. A total of 572 sputum samples were collected from cystic fibrosis patients along with the patient demographic details in a questionnaire. In total, 217 P. aeruginosa isolates were collected and an antibiogram revealed that 159 (73.3%) and 141 (64.9%) of these colonies exhibited resistance to imipenem and meropenem, respectively. Ceftazidime and tobramycin resistance were both identified in 112 (51.6%) isolates, and resistance to piperacillin-tazobactam, gatifloxacin and netilmicin was detected in 96 (44.2%) respective samples. A total of 62 (28.6%) respective samples were resistant to cefoperazone, cefepime and ceftriaxone. The least antibiotic resistance was shown to amikacin and ceftizoxime with 51 (23.5%) and 32 (14.7%) respective colonies resistant to the antibiotics. The minimum inhibitory concentration (MIC) for imipenem revealed a reduction in the MIC values. MBL screening by the zone enhancement method using ceftazidime plus EDTA discs demonstrated that 63 (56.25%) of the colonies were positive for MBL. A total of 53 (84.1%) samples expressed blaVIM and 48 (76.1%) expressed blaIMP genes, as detected by duplex polymerase chain reaction. In conclusion, carbapenem resistance is of great clinical concern in cystic fibrosis patients with P. aeruginosa infection. Therefore, mandatory regular screening and monitoring the resistance in P. aeruginosa among CF patients is required.


Shi D.-L.,Henan Hospital of Traditional Chinese Medicine | Yang H.,Henan Hospital of Traditional Chinese Medicine | He Z.-K.,Henan Hospital of Traditional Chinese Medicine | Wang Z.-H.,Henan University of Traditional Chinese Medicine
Chinese Journal of Tissue Engineering Research | Year: 2013

Background: Bone morphogenetic protein 2 and LIM mineralization protein 1 play an important role in osteoblast differentiation and maturation, which are greatly associated with cervical diseases. Objective: To observe the influence of Liubaichangsha granule on bone morphogenetic protein 2 and LIM mineralization protein 1 in the peripheral serum of cervical disease rabbit models. Methods: Fifty adult rabbits were randomly divided into five groups. Cervical disease models were made through keeping squatting and head-bending position in all the groups except for the normal control group. Intragastric administration of 0.25 g Jingfukang granule, 0.5 g Liubaichangsha granule and 0.25 Liubaichangsha granule per day was performed respectively in the Jingfukang group, low-dose and high-dose Liubaichangsha groups. The same volume of diluted water was given in the normal control and model groups. All the rabbits were examined with roentgenogram and dual energy radiograph absorptiometry for the cervical vertebrae in the 4th and 12th weeks, the pathology of the cervical intervertebra discs were measured in the 12th week, and bone morphogenetic protein 2 and LIM mineralization protein 1 levels in the peripheral blood serum were determined and observed in the 12th week. Results and Conclusion: The bone morphogenetic protein 2 and LIM mineralization protein 1 levels in the high-dose Liubaichangsha group were significantly higher than those in the normal control, model and low-dose Liubaichangsha groups (P < 0.05). The model group had a lower levels of bone morphogenetic protein 2 and LIM mineralization protein 1 as compared with the normal control, Jingfukang and high-dose Liubaichangsha groups (P < 0.05), but not differ from the low-dose Liubaichangsha group (P > 0.05). These findings indicate that Liubaichangsha granule can increase the levels of bone morphogenetic protein 2 and LIM mineralization protein 1 so as to cure cervicaldiseases.


Gao Z.,Henan University of Traditional Chinese Medicine | Yu H.,Henan Hospital of Traditional Chinese Medicine
Proceedings - 2013 5th International Conference on Intelligent Human-Machine Systems and Cybernetics, IHMSC 2013 | Year: 2013

Aimed at solving the data packet loss problems using target tracking methods in WSN, analyzs several mathematical model and algorithm with uncertain observation filter can achieve it Based on Kalman filter framework, thus establish WSN target tracking filter simulation model, and use the algorithm simulation test was carried out. Simulation results show that the different model under uncertain observation filtering method of filtering effect is different, multi-step packet loss model applied to moving target tracking in WSN has excellent tracking performance. © 2013 IEEE.


Cao Y.,Henan Hospital of Traditional Chinese Medicine | Lv Q.,Henan Hospital of Traditional Chinese Medicine | Lv C.,Henan University of Traditional Chinese Medicine
International Journal of Molecular Medicine | Year: 2015

Elucidation of the molecular mechanisms governing the osteogenic differentiation of human mesenchymal stem cells (hMSCs) is of great importance for improving the treatment of bone-related diseases. MicroRNAs (miRNAs or miRs), a class of small non-coding RNAs, are critical in a number of biological processes, including the proliferation, differentiation and survival of cells and organisms. Emerging evidence indicates that miRNAs are essential in regulating osteoblastogenesis and bone formation. However, the role of miRNAs in osteoblast mechanotransduction remains to be defined. The present study aimed to examine the role of miR-153 in the osteogenesis of hMSCs and to investigate the impact of miR-153 on bone morphogenetic protein receptor type II (BMPR2) expression. The overexpression of miR-153 inhibited the osteogenic differentiation of hMSCs, whereas downregulation of miR-153 enhanced the process. Furthermore, bioinformatic analysis predicted that miR-153 is a potential regulator of BMPR2. The direct binding of miR-153 to the BMPR2 3'-untranslated region (3'-UTR) was demonstrated by a luciferase reporter assay using a construct containing the BMPR2 3'-UTR. In addition, knockdown of BMPR2 by RNA interference inhibited the osteogenic differentiation of hMSCs, with a similar effect to the upregulation of miR-153. In conclusion, the results suggest that miR-153 is a mechano-sensitive miRNA that regulates osteoblast differentiation by directly targeting BMPR2, and that therapeutic inhibition of miR-153 may be an efficient anabolic strategy for skeletal disorders caused by pathological mechanical loading.


Liu Y.-J.,Henan University of Traditional Chinese Medicine | Dai D.-S.,Henan Hospital of Traditional Chinese Medicine
Acta Crystallographica Section E: Structure Reports Online | Year: 2012

The asymmetric unit of the title compound, C7H7BrIN, contains two independent mol-ecules, which are linked by weak N-H⋯N hydro-den-bonding inter-actions between the amino groups.


Niu X.,Henan Hospital of Traditional Chinese Medicine
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology | Year: 2013

To establish the evaluation reference for domestic anti-hepatitis C virus (HCV) enzyme immunoassay (EIA) diagnostic kits. 4833 serum samples which were collected from different provinces of China were screened with 5 domestic anti-HCV EIA kits and redetected with 2 foreign anti-HCV EIA kits. Then the selected samples were confirmed with Chiron RIBA HCV 3.0 SIA and real-time quantitative PCR reagents. The confirmed positive samples were examined for HCV genotypes. The positive samples (classified as low, medium and high titers), negative samples, mixed-titer positive dilution samples and special samples were selected for preparing the evaluation reference for anti-HCV diagnostic reagent kits. The established evaluation reference consisted of 30 positive serum samples including high, medium and low titers, and 10 single band samples confirmed by RIBA, and 6 dilution samples to evaluate the sensitivity, and 30 confirmed negative samples including some high negative value samples and interferential samples. The evaluation reference samples could offer dependable detection results, and covered abundant antibody repertoire, thus providing important reference for the improvement of the qualities of domestic anti-HCV EIA kits.


PubMed | Henan Hospital of Traditional Chinese Medicine
Type: Journal Article | Journal: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology | Year: 2013

To establish the evaluation reference for domestic anti-hepatitis C virus (HCV) enzyme immunoassay (EIA) diagnostic kits.4833 serum samples which were collected from different provinces of China were screened with 5 domestic anti-HCV EIA kits and redetected with 2 foreign anti-HCV EIA kits. Then the selected samples were confirmed with Chiron RIBA HCV 3.0 SIA and real-time quantitative PCR reagents. The confirmed positive samples were examined for HCV genotypes. The positive samples (classified as low, medium and high titers), negative samples, mixed-titer positive dilution samples and special samples were selected for preparing the evaluation reference for anti-HCV diagnostic reagent kits.The established evaluation reference consisted of 30 positive serum samples including high, medium and low titers, and 10 single band samples confirmed by RIBA, and 6 dilution samples to evaluate the sensitivity, and 30 confirmed negative samples including some high negative value samples and interferential samples.The evaluation reference samples could offer dependable detection results, and covered abundant antibody repertoire, thus providing important reference for the improvement of the qualities of domestic anti-HCV EIA kits.

Loading Henan Hospital of Traditional Chinese Medicine collaborators
Loading Henan Hospital of Traditional Chinese Medicine collaborators