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Pavliš, Serbia

Mladenovic A.R.,Hemofarm AD | Mijin D.Z.,University of Belgrade | Drmanic S.Z.,University of Belgrade | Vajs V.E.,University of Belgrade | And 3 more authors.

The oxidative ability of donepezil, a frequently prescribed drug for the treatment of Alzheimer's disease is reported for the first time at a gold electrode. It was oxidized by cyclic voltammetry and determined by square wave voltammetry in phosphate buffer electrolyte. Electrochemical degradation of donepezil was carried out by long term potential cycling. The identification and characterization of the major product, isolated by preparative high performance liquid chromatography, was performed by high resolution mass spectrometry and 1D and 2D nuclear magnetic resonance spectroscopy. Donepezil hydroxy derivative was identified as the major electrochemical oxidation product from donepezil. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Source

The subject and the research objective presented in this article is establishing of the relationship between quality assurance and implementation of cleaner production in the generic pharmaceutical industry through the comprehensive concept of continuous improvement. This is mostly related to application of Lean and Six Sigma tools and techniques for process improvement and their link to other known concepts used in the industrial environment, especially manufacturing of generic pharmaceutical products from which two representative case studies were selected for comparative analysis, also considering relevant regulatory requirements in the field of quality management, as well as appropriate quality standards. Although the methodology discussed in this conceptual and practice oriented article is strongly related to chemical engineering, the focus is mainly on process industry, i.e., production systems, rather than any specific technological process itself. The scope of this research is an engineering approach to evaluation of the production systems in terms of continuous improvement concepts application, considering both quality aspects and efficiency of such systems. © 2016, CI and CEQ. All rights reserved. Source

Todorovic-Dudic A.,Hemofarm AD
International Journal of Industrial Engineering and Management

The strategic playing field of controllers from the perspective of the services to be delivered and the relationships to internal customer, were frequent references to how controllers should adapt their abilities to such challenges. Controllers should therefore under no circumstances take comfort in their very strong internal competitive position, but have to work actively on its ongoing strategic development. If controllers focus consistently on identifying new services for managers, if they keep their managers' satisfaction in mind, if they measure their tasks in the same way that they plan and monitor business development, then there are strong arguments why they should be able to maintain their market dominance in the area of management support. Source

Voskresenski V.,Hemofarm AD | Voskresenski K.,Technical Faculty Mihajlo Pupin | Odadzic V.,Zrenjaninska gimnazija
Technics Technologies Education Management

By applying analysis of differences in development of curriculum concept, the authors present the idea that two basic structural components of this concept can be identified. This is discussed in the first part of the thesis. The second part of the thesis gives practical possibilities of tuition planning according to the curriculum methodology using the example of Electrical Engineering teaching. The third, central and according to the authors, most significant part of the essay, points out that the curriculum components are, both by their structure and logical sequence, fully compatible with the subsystems and elements of control in cybernetic systems. Hence the belief of the authors that tuition planning using the methodology of curriculum modeled in cybernetic regulatory circle could create possibilities of managing, regulation and more impartial evaluation of the overall tuition planning process. The validity of such affirmations is justified by a short illustration of application of this concept in all educational systems, with minor exceptions, its effects being established only by application of classical positivistic pedagogical methodology. Source

The world today faces a considerable growth and spreading of telecommunication networks. Mobile communications companies have to build a sufficient number of base transceiver stations (BTSs) in order to provide high-quality mobile communications services for their customers. Maintenance of such dislocated technical systems is very demanding regarding the engaged manpower and maintenance expenses. The paper shows a modeled system of remote monitoring of parameters of uninterruptible power supply system for telecommunication devices within base transceiver stations in mobile telephony. In their research work the authors of the paper have discovered that application of modern information-telecommunication technologies in remote monitoring of technical systems contributes to increase of reliability and quality of mobile telephony services along with decrease of maintenance expenses. The importance of this paper lies in the attempt to recognize development tendencies and application of new information-telecommunication technologies in the process of maintenance of technical systems. Source

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