Hematology and Blood Transfusion Unit

Abeokuta, Nigeria

Hematology and Blood Transfusion Unit

Abeokuta, Nigeria
SEARCH FILTERS
Time filter
Source Type

Motayo B.O.,Microbiology Unit | Motayo B.O.,University of Ibadan | Faneye A.O.,University of Ibadan | Udo U.A.,Hematology and Blood Transfusion Unit | And 4 more authors.
African Health Sciences | Year: 2015

Background: Transfusion transmissible infections, such as HIV, HBV, HCV and syphilis are on the rise and pose a threat to blood safety. Objective: To determine prevalence and demographic profiles of TTI’s among first time blood donors in Abeokuta, Nigeria. Methods: The study was conducted between February to November 2013; 130 first time blood donors were tested for the presence of HIV, HBsAg, HCV antibodies and Treponema palidium antibodies using EIA based rapid immunochromatographic kits. Data analysis was done using SPSS with a level of significance of p<0.05. Results: Prevalence rates to HIV, HBsAg, HCV antibody, were 6.2% (n=8), 10% (n=13) and 1.5% (n=2), there was 0% prevalence to Treponema palidium antibodies. Group specific prevalence rates revealed that educational status was associated with HBsAg positivity (p = 0.028), donors with a history of previous blood transfusion was also statistically associated with HIV sero-reactivity (p = 0.013). Conclusions: High levels of HBsAg and HIV were observed, there is need to revise the donor testing algorithm in Nigeria in line with the prevalence of TTI’s. We also advocate that a National surveillance system for TTI’s be established through our National blood transfusion service (NBTS) program, a second serological test is also suggested to reduce the risk of occult HBV infection in Nigeria. © Makerere University, Medical School. All rights reserved.


PubMed | Microbiology Unit, Hematology and Blood Transfusion Unit and University of Ibadan
Type: Journal Article | Journal: African health sciences | Year: 2015

Transfusion transmissible infections, such as HIV, HBV, HCV and syphilis are on the rise and pose a threat to blood safety.To determine prevalence and demographic profiles of TTIs among first time blood donors in Abeokuta, Nigeria.The study was conducted between February to November 2013; 130 first time blood donors were tested for the presence of HIV, HBsAg, HCV antibodies and Treponema palidium antibodies using EIA based rapid immunochromatographic kits. Data analysis was done using SPSS with a level of significance of p<0.05.Prevalence rates to HIV, HBsAg, HCV antibody, were 6.2% (n=8), 10% (n=13) and 1.5% (n=2), there was 0% prevalence to Treponema palidium antibodies. Group specific prevalence rates revealed that educational status was associated with HBsAg positivity (p = 0.028), donors with a history of previous blood transfusion was also statistically associated with HIV sero-reactivity (p = 0.013).High levels of HBsAg and HIV were observed, there is need to revise the donor testing algorithm in Nigeria in line with the prevalence of TTIs. We also advocate that a National surveillance system for TTIs be established through our National blood transfusion service (NBTS) program, a second serological test is also suggested to reduce the risk of occult HBV infection in Nigeria.

Loading Hematology and Blood Transfusion Unit collaborators
Loading Hematology and Blood Transfusion Unit collaborators