Trieste, Italy
Trieste, Italy

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Ruiz-Gonzalez Y.,University "Marta Abreu" of Las Villas | Perez-Diaz M.,University "Marta Abreu" of Las Villas | Martinez-Aguila D.,University "Marta Abreu" of Las Villas | Diaz-Barreto M.,Centro Para El Control Estatal Of Medicamentos | And 5 more authors.
International Journal of Computer Assisted Radiology and Surgery | Year: 2016

Purpose: Phase-contrast mammography with synchrotron radiation is an innovative X-ray imaging practice that improves the identification of breast lesions. Previous studies have proven the superiority of the mammography images taken in the phase-contrast modality using synchrotron radiation beams as compared with images taken in conventional mammography by subjective analyses. However, to our knowledge, no previous study has compared different acquisition systems in order to quantify this improvement by means of objective robust indicators. In this research, we intend to quantify the superiority of phase-contrast imaging by means of objective metrics of image quality. Methods: Images from the American College of Radiology Mammographic Accreditation Phantom were obtained at hospitals, in two digital mammography equipment and at the Elettra synchrotron radiation facility (Trieste, Italy), using free space propagation phase-contrast modality. Regions of interest were selected to analyze image quality at the fibers (phase object) and masses (area object) simulated on the phantom by means of the signal-to-noise ratio, the figure of merit, the contrast and the edge visibility. Results: The image contrast and edge visibility were significantly higher at the phase-contrast modality as compared with digital mammography equipment. The figure of merit using phase-contrast modality was higher for the fibers and comparable for the masses. Conclusion: The results showed an improvement of the contrast and edge visibility in phase-contrast images. These improvements may be important in the detection of small lesions and details. © 2015, CARS.


Valeri G.,Clinical Radiology | Mazza F.A.,Radiology Postgraduate School | Maggi S.,Health Physics | Aramini D.,AOU Ospedali Riuniti | And 3 more authors.
Radiologia Medica | Year: 2015

Materials and methods: We selected 23 programs for Windows and 20 programs for Mac from 150 possible OSS programs including DICOM viewers and various tools (converters, DICOM header editors, etc.). The programs selected all meet the basic requirements such as free availability, stand-alone application, presence of graphical user interface, ease of installation and advanced features beyond simple display monitor. Capabilities of data import, data export, metadata, 2D viewer, 3D viewer, support platform and usability of each selected program were evaluated on a scale ranging from 1 to 10 points.Purpose: The purpose of this paper is to evaluate the use of open source software (OSS) to process DICOM images.Results: Twelve programs received a score higher than or equal to eight. Among them, five obtained a score of 9: 3D Slicer, MedINRIA, MITK 3M3, VolView, VR Render; while OsiriX received 10.Conclusions: OsiriX appears to be the only program able to perform all the operations taken into consideration, similar to a workstation equipped with proprietary software, allowing the analysis and interpretation of images in a simple and intuitive way. OsiriX is a DICOM PACS workstation for medical imaging and software for image processing for medical research, functional imaging, 3D imaging, confocal microscopy and molecular imaging. This application is also a good tool for teaching activities because it facilitates the attainment of learning objectives among students and other specialists. © 2014, Italian Society of Medical Radiology.


PubMed | Elettra - Sincrotrone Trieste, University of Trieste, Health Physics, University "Marta Abreu" of Las Villas and Centro Para El Control Estatal Of Medicamentos
Type: Journal Article | Journal: International journal of computer assisted radiology and surgery | Year: 2016

Phase-contrast mammography with synchrotron radiation is an innovative X-ray imaging practice that improves the identification of breast lesions. Previous studies have proven the superiority of the mammography images taken in the phase-contrast modality using synchrotron radiation beams as compared with images taken in conventional mammography by subjective analyses. However, to our knowledge, no previous study has compared different acquisition systems in order to quantify this improvement by means of objective robust indicators. In this research, we intend to quantify the superiority of phase-contrast imaging by means of objective metrics of image quality.Images from the American College of Radiology Mammographic Accreditation Phantom were obtained at hospitals, in two digital mammography equipment and at the Elettra synchrotron radiation facility (Trieste, Italy), using free space propagation phase-contrast modality. Regions of interest were selected to analyze image quality at the fibers (phase object) and masses (area object) simulated on the phantom by means of the signal-to-noise ratio, the figure of merit, the contrast and the edge visibility.The image contrast and edge visibility were significantly higher at the phase-contrast modality as compared with digital mammography equipment. The figure of merit using phase-contrast modality was higher for the fibers and comparable for the masses.The results showed an improvement of the contrast and edge visibility in phase-contrast images. These improvements may be important in the detection of small lesions and details.


Suman V.,Health Physics | Datta D.,Health Physics | Sarkar P.K.,Health Physics | Kushwaha H.S.,Bhabha Atomic Research Center
Indian Journal of Pure and Applied Physics | Year: 2010

Radiation transport calculations for shielding studies in the field of accelerator technology often involve intensive numerical computations. Traditionally, radiation transport equation is solved using finite difference scheme or advanced finite element method with respect to specific initial and boundary conditions suitable for the geometry of the problem. All these computations need CPU intensive computer codes for accurate calculation of scalar and angular fluxes. Computation using symbols of the analytical expression representing the transport equation as objects is an enhanced numerical technique in which the computation is completely algorithm and data oriented. Algorithm on the basis of symbolic math architecture is developed using Symbolic math toolbox of MATLAB software. Present paper describes the symbolic math algorithm and its application as a case study in which shielding calculation of rectangular slab geometry is studied for a line source of specific activity. Study of application of symbolic math in this domain evolves a new paradigm compared to the existing computer code such as DORT.


Valeri G.,Clinical Radiology | Cegna S.,UNIVPM | Mari A.,Health Physics | La Riccia L.,AOU Ospedali Riuniti | And 3 more authors.
Radiologia Medica | Year: 2015

Purpose: This study was done to evaluate the appropriateness of dose indices in computed tomography (CT) by comparing the body computed tomography dose index (CTDI) and the size-specific dose estimates (SSDE) to determine which of these two parameters is more appropriate to estimate the radiation dose to both adult and paediatric patients. Materials and methods: We analysed 150 thoracic CT and 150 abdominal CT scans, half of which from adult patients and the other half from paediatric patients. We compared the values of the CTDIvol and the SSDE reporting the average, maximum and minimum percentage difference for each body region and depending on the age of the patients. Results: In the thoracic CT and abdominal CT scans, we found values of difference between the SSDE and the CTDIvol of 26.3 and 27.3 %, respectively, in adult patients and of 46.9 and 48.5 % in paediatric patients. Conclusions: The SSDE is a good tool for estimating the average radiation dose for a given patient depending on the input parameters and the dimensions of the specific person in question before a CT examination. © 2014, Italian Society of Medical Radiology.


Marini C.,CNR Institute of Neuroscience | Seitun S.,Interventional Radiology | Zawaideh C.,Clinic of Cardiovascular Diseases | Bauckneht M.,Nuclear Medicine | And 16 more authors.
Journal of Nuclear Cardiology | Year: 2016

Background: Recent technical advances in multi-detector computed tomography (MDCT) allow for assessment of coronary flow reserve (CFR). We compared regional CFR by dynamic SPECT and by dynamic MDCT in patients with suspected or known coronary artery disease (CAD). Methods: Thirty-five patients, (29 males, mean age 69 years) with greater than average Framingham risk of CAD, underwent dipyridamole vasodilator stress imaging. CFR was estimated using dynamic SPECT and dynamic MDCT imaging in the same patients. Myocardial perfusion findings were correlated with obstructive CAD (≥50% luminal narrowing) on CT coronary angiography (CA). Results: Mean CFR estimated by SPECT and MDCT in 595 myocardial segments was not different (1.51 ± 0.46 vs. 1.50 ± 0.37, p = NS). Correlation of segmental CFR by SPECT and MDCT was fair (r2 = 0.39, p < 0.001). Bland-Altman analysis revealed that MDCT in comparison to SPECT systematically underestimated CFR in higher CFR ranges. By CTCA, 12 patients had normal CA, 11 had non-obstructive, and 12 had obstructive CAD. CFR by both techniques was significantly higher in territories of normal CA than in territories subtended by non-obstructive or obstructive CAD. SPECT CFR was also significantly different in territories subtended by non-obstructive and obstructive CAD, whereas MDCT CFR was not. Conclusion: Despite relative underestimation of high CFR values, MDCT CFR shows promise for assessing the pathophysiological significance of anatomic CAD. © 2016 American Society of Nuclear Cardiology


PubMed | Nuclear Medicine, CNR Institute of Neuroscience, Epidemiology Unit, University of Genoa and 3 more.
Type: | Journal: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology | Year: 2016

Recent technical advances in multi-detector computed tomography (MDCT) allow for assessment of coronary flow reserve (CFR). We compared regional CFR by dynamic SPECT and by dynamic MDCT in patients with suspected or known coronary artery disease (CAD).Thirty-five patients, (29 males, mean age 69 years) with greater than average Framingham risk of CAD, underwent dipyridamole vasodilator stress imaging. CFR was estimated using dynamic SPECT and dynamic MDCT imaging in the same patients. Myocardial perfusion findings were correlated with obstructive CAD (50% luminal narrowing) on CT coronary angiography (CA).Mean CFR estimated by SPECT and MDCT in 595 myocardial segments was not different (1.510.46 vs. 1.500.37, p=NS). Correlation of segmental CFR by SPECT and MDCT was fair (r Despite relative underestimation of high CFR values, MDCT CFR shows promise for assessing the pathophysiological significance of anatomic CAD.

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