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Celik T.,Bolu Gerede State Hospital | Yuksel D.,Ankara Nuclear Research And Training Center | Kosker M.,Ulus State Hospital | Kasim R.,Ankara Nuclear Research And Training Center | Simsek S.,Haydarpasa Training and Research Hospital
Current Eye Research | Year: 2015

Abstract Purpose: To evaluate the fibrovascular in-growth of coralline and synthetic hydroxyapatite orbital implants by reporting the enhancement patterns on Gadolinium-Dietilen triamin penta acetic acid (Gad-DTPA) enhanced magnetic resonance imaging (MRI). Methods: The medical records of 26 patients who had undergone primary or secondary orbital implantation between April 2008 and February 2011 were reviewed. T1 weighted Gad-DTPA MRI was performed between 5 and 12 months (mean 9.2 ± 5.9 months) after implantation and graded as follows to evaluate the fibrovascular in-growth of the implants; grade 1 (rim enhancement), grade 2 (peripheral foci of enhancement, not including the center), grade 3 (central, non-homogenous enhancement), grade 4 (central, homogenous enhancement) and grade 5 (central, intense enhancement).Results were analysed according to vascularization patterns on Gad-DTPA MRI. Results: Central vascularization patterns (grade 3, 4 or 5) were seen 62.5% of coralline orbital implants and 46.1% of synthetic orbital implants. Central fibrovascular in-growth of the coralline implants were found significantly more than synthetic implants (p < 0.05). Central vascularization of coralline implants with primary implantation was 75% and with secondary implantation was 50%. Synthetic orbital implantation with primary surgery demonstrated 66.6% and synthetic orbital implantation with secondary surgery demonstrated 26.6% central vascularization pattern. In both natural coralline and synthetic implants, primary orbital implantation was demonstrated significantly better fibrovascular in-growth than secondary implantation (p < 0.05). Two patients with synthetic orbital implants had dehiscence that was repaired by using autogenous fascia lata. Conclusions: In both coralline and synthetic orbital implants, central vascular in-growth was observed much more with primary orbital implantation. This study indicates that coralline HA orbital implants significantly supply more rapid and homogenous vascularization than synthetic implants. © 2014 Informa Healthcare USA, Inc. All rights reserved: reproduction in whole or part not permitted.

Koyuncu H.,Yeditepe University | Serefoglu E.C.,Kzltepe State Hospital | Yencilek E.,Haydarpasa Training and Research Hospital | Atalay H.,Yeditepe University | And 2 more authors.
International Journal of Impotence Research | Year: 2011

The aim of this study was to determine the impact of long-term escitalopram treatment on semen parameters of patients with lifelong premature ejaculation (PE). Between November 2008 and January 2010, patients admitted to urology outpatient clinic with a self-reported complaint of PE were evaluated. Medical and sexual history of patients were recorded and patients with lifelong PE (a total of 25 patients) who met the International Society of Sexual Medicine definition were asked to record their intravaginal ejaculatory latency time (IELT) for 1 month, complete Premature Ejaculation Diagnostic Tool (PEDT) questionnaire and give semen samples. Afterwards, patients received 10 mg escitalopram daily for 12 weeks and were invited for control visits at first and third month of treatment. During control visits, PEDT was administered again whereas IELTs were recorded and semen samples were re-examined. PEDT scores, arithmetic means of IELTs and results of semen analyses, which were recorded at baseline, first and third month were compared. At the third month of treatment, a significant increase in mean IELTs and a significant decrease in PEDT scores were detected. However there was a significant decrease in sperm concentration, motility and morphology when compared with the baseline semen measures. Daily escitalopram treatment effects the semen parameters of patients with lifelong PE. Further investigations with larger series are needed to see whether other serotonin reuptake inhibitors have similar side effects and to expose the exact mechanism underlying it. Different treatment modalities should be suggested to patients who desire fertility. © 2011 Macmillan Publishers Limited All rights reserved.

Yenigun A.,Bezmialem Foundation University | Meric A.,Bezmialem Foundation University | Verim A.,Haydarpasa Training and Research Hospital | Ozucer B.,Bezmialem Foundation University | And 2 more authors.
European Archives of Oto-Rhino-Laryngology | Year: 2012

A novel method for repair of septal perforations. Fifteen volunteers with symptomatic septal perforations were recruited. Open technique rhinoplasty approach was preferred: auricular conchal cartilage graft with intact perichondrium on both sides was harvested and shaped to fit the perforated site and attached to the septum with absorbable sutures. All margins of the graft were covered with nasal mucosa. The severity of patient symptoms was assessed at preoperation, 3 and 6 months postoperatively via visual analogue scale (VAS). Crust formation, whistling, nasal blockage, epistaxis and overall comfort were evaluated. Mucosal physiology was assessed by nasal mucociliary clearance time. The mean age of the patients was 47.3 years. Average perforation size was 1.86 ± 0.78 cm. 14/15 (93.3%) perforations were repaired, and only one patient required revision surgery. VAS scores improved significantly (p < 0.001). Mean mucociliary clearance time improved from 17.6 ± 3.83 to 10.3 ± 3.30 min and 9.3 ± 3.36 min at 3 and 6 months, respectively. This is a novel, simple and safe method for repairing the deficient mucosal area in septal perforations up to 25 mm in diameter. © Springer-Verlag 2012.

Ozturk A.,Dumlupinar University | Deveci E.,Bezmialem Foundation University | Bagcioglu E.,Afyon Kocatepe University | Atalay F.,Pendik State Hospital | Serdar Z.,Haydarpasa Training and Research Hospital
Turkish Journal of Medical Sciences | Year: 2013

Aim: To investigate the psychiatric characteristics of acne vulgaris and the effects of the disease on quality of life. Materials and methods: We included 70 acne patients and 50 healthy controls. The Structured Clinical Interview for DSM-IV Axis I Disorders, Hospital Anxiety and Depression Scale, Liebowitz Social Anxiety Scale, Quality of Life Scale Short Form, and Acne Quality of Life Questionnaire were applied. Results: Anxiety and depression scores of the acne patients were significantly higher than those of the control group. In patients with acne, significantly higher levels of social anxiety were detected. Social anxiety levels of severe acne cases were significantly higher. Social phobia was the most common axis I disorder. According to the SF-36 scale, vitality, social functioning, and emotional role difficulty scores were significantly higher in acne patients. Conclusion: Especially when acne vulgaris is severe, psychiatric evaluation and psychotherapeutic interventions particularly aimed at social anxiety symptoms and social functioning should be important parts of the treatment plan. © TÜBİTAK.

Kaya B.,Fatih Sultan Mehmet Training and Research Hospital | Eris C.,Haydarpasa Training and Research Hospital
Clinical Medicine Insights: Pathology | Year: 2011

An appendicolith is composed of firm feces and some mineral deposits. After increased use of abdominal computed tomography, appendicoliths are more frequently detected. Most of the patients with appendicolith are asymptomatic. However, an appendicolith may be associated with complicated appendicitis with serious outcomes. We reported three patients who exhibited different clinical symptoms due to appendicolithiasis. While one of the patients was confused with urolithiasis, the other two patients presented with phlegmenous and perforated appendicitis. We submit that appendicoliths may present different clinical findings and can mimic several pathologies including urinary disorders. © the author(s), publisher and licensee Libertas Academica Ltd.

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