Haydarpasa Research and Training Hospital

İstanbul, Turkey

Haydarpasa Research and Training Hospital

İstanbul, Turkey
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Yenerel N.M.,Haydarpasa Research and Training Hospital | Kucumen R.B.,Yeditepe University
Turk Oftalmoloiji Dergisi | Year: 2015

Pregnancy causes significant changes in all systems of the body. Although most of them are physiological, they may also lead to pathological consequences. The resulting pathological changes may occur for the first time or existing diseases affected by pregnancy can become more serious or change course. Diseases specific only to pregnancy may arise. Like all systems of the body, the visual system is also affected by pregnancy, developing a wide range of physiological and pathological changes. Knowing the ocular physiological changes and diagnosing eye diseases that may develop during pregnancy, and preventing and treating these diseases is crucial to ensure the baby’s healthy development. Therefore, we have reviewed the conditions that an ophthalmologist should recognize, follow-up, and pay attention to during treatment and summarized them under the topic “pregnancy and the eye”. © 2015, Turkish Ophthalmology Society. All rights reserved.


Bez Y.,Dicle University | Kinis V.,Ergani State Hospital | Naiboglu B.,Haydarpasa Research and Training Hospital
International Journal of Pediatric Otorhinolaryngology Extra | Year: 2011

Various types of foreign bodies in external ear canals are commonly seen especially in children. They are usually managed without any severe complications if handled by trained personnel. Presentation of foreign bodies in both external ear canals is rarely encountered. Furthermore, repeated admission of a child with bilateral external ear involvement is also not reported before. Here, we present a 4 years old boy with repeated admission after inserting stones into his ear canals and discuss the behavioral correlates and their implications to otorhinolaryngology practice. © 2010 Elsevier Ireland Ltd.


Remzi Erdem M.,Haydarpasa Research and Training Hospital | Tepeler A.,Bezmialem Foundation University | Gunes M.,Bezmialem Foundation University | Silay M.S.,Bezmialem Foundation University | And 4 more authors.
Journal of the Society of Laparoendoscopic Surgeons | Year: 2014

Background and Objectives: In this study, we evaluated the safety and efficacy of using the LigaSure sealing system (Valleylab, Boulder, Colorado) for laparoscopic decortication of symptomatic hilar renal cysts. Methods: Seventeen patients underwent laparoscopic decortication of hilar renal cysts with the LigaSure system. Our study included only symptomatic, Bosniak type 1, simple and symptomatic renal cysts. The operative route, transperitoneal or retroperitoneal, was planned according to the location confirmed by computed tomography. The patients' symptoms were preoperatively and postoperatively evaluated by the Wong-Baker visual pain scale. Operative measures and radiologic outcomes were prospectively evaluated. Results: The mean age of the patients was 56.4 years, and the mean follow-up period was 12.5 months. Preoperative computed tomography showed only a single cyst in 15 patients (88.2%) and showed two separate cysts in 2 cases (11.8%). The cysts were located in the perihilar region close to the vascular structure in all patients. A transperitoneal approach was used in 9 patients, and a retroperitoneal approach was used in 8 patients. The mean operative time and hospitalization time were 56.4 minutes and 1.2 days, respectively. Minor complications were observed in 3 patients. Symptomatic and radiologic success rates of 94.2% and 100%, respectively, were achieved. Conclusion: Laparoscopic decortication of symptomatic hilar renal cysts-first reported in the literature in this study-using the LigaSure sealing system is feasible, effective, and safe, even if the cyst is located in the perihilar area. © 2014 by JSLS, Journal of the Society of Laparoendoscopic Surgeons.


Yigit S.,Gebze Fatih State Hospital | Sahin Z.,Haydarpasa Research and Training Hospital | Demir S.E.,Bezmialem Foundation University | Aytac D.H.,Haydarpasa Research and Training Hospital
Rheumatology International | Year: 2013

The importance of exercise and regular physiotherapy in patients with ankylosing spondylitis (AS) under treatment with tumor necrosis factor alpha inhibitors (TNFα inhibitors) was reported in some studies, but the literature on this topic is still scarce. The aim of this study was to assess the effects of home-based exercise therapy on functional capacity, disease activity, spinal mobility, quality of life, emotional state and fatigue in patients with AS receiving TNFα inhibitors. Forty-two AS patients were trained on the disease, and home-based exercise program was demonstrated to all the patients. At baseline and at the end of 10 week, we evaluated Bath AS Disease Activity Index, Bath AS Functional Index, Bath AS Metrology Index, Multidimensional Assessment of Fatigue Scale, Beck Depression Inventory and Short-Form 36. Patients following home-based exercise program five times a week at least 30 min per session (exercise group) were compared with those exercising less than five times a week (control group). At baseline, exercise and control group had similar demographic features. After 10 weeks, all outcome parameters showed statistically significant improvements in exercise group. There were significant differences in all the parameters except social functioning subscale of Short-Form 36 between groups in favor of exercise group at 10th week (P < 0.05). Home-based exercise program is an effective therapy in increasing functional capacity and joint mobility, decreasing disease activity, improving emotional state, fatigue and quality of life for AS patient receiving TNFα inhibitors. We need to find out new ways to provide continuity of AS patients with it. © 2012 Springer-Verlag.


Colak S.,Haydarpasa Research and Training Hospital | Erdogan M.O.,Haydarpasa Research and Training Hospital | Sogut O.,Bezmialem Foundation University | Yigit M.,Bezmialem Foundation University
Acta Medica Mediterranea | Year: 2014

Aims: The aim of this study is to evaluate the epidemiologic features of gluteal penetrating injuries (GPIs) and the effect of anatomic localization and muscle tissue penetration in severe cases. Methods: Forty-two patients admitted to our hospital emergency service between 2010 and 2012 for gluteal penetrating injuries were included in the study. Hospital records were evaluated retrospectively. Results: Thirty-six (85.7%) patients were male, and six (14%) patients were female. The mean age was 32.55 ± 12.85. Seven (31.8%) of the lower GPI patients had soft tissue haematomas, seven (31.8%) had intramuscular haematomas, two (9%) had vascular injuries, one (4.5%) had a peritoneal injury, one (4.5%) had a bone fracture and one (4.5%) had nerve injury. None in this group had rectal injury. Three (13.6%) of lower GPI patients were classified as severe injury, and all had muscle penetration. Eight (31.8%) of the upper GPI patients had soft tissue hematomas, 10 (50%) had intramuscular hematomas, three (15%) had intraperitoneal injuries, one (5%) had a rectum injury and one (5%) had vascular injury. None in this group had bone fracture or nerve injury. Five (25%) of the upper GPI patients were classified as severe injuries. Lower and upper GPI localizations were not related to the severity of the injury (p > 0.05). Severe injuries were more common in patients with muscle penetration (p < 0.004). Conclusions: Gluteal penetrating injuries (GPIs) are rare. These injuries are usually superficial and can be treated with local wound care. Severe and life-threating injuries might occur in GPIs, and our study showed that severe injuries can be seen in upper and lower GPIs. Anatomic classification did not predict the severity of injury. We recommend wound exploration in the initial evaluation of all GPIs. Patients with evidence of muscle penetration should be evaluated with further diagnostic imaging.


Ozel L.,Haydarpasa Numune Research and Training Hospital | Toros S.Z.,Haydarpasa Numune Research and Training Hospital | Unal E.,Haydarpasa Numune Research and Training Hospital | Kara M.,Haydarpasa Numune Research and Training Hospital | And 4 more authors.
Experimental and Clinical Transplantation | Year: 2011

Ramsay Hunt syndrome is a rare complication of herpes zoster disease in which reactivation of latent varicella zoster virus infection occurs in the geniculate ganglion causing otalgia, unilateral vesicular eruption in a restricted dermatomal distribution, and peripheral facial paralysis. Dermal infections caused by human pathogenic herpes viruses are common in organ transplant recipients. For a transplant surgeon, it is imperative to remember that viral prophylaxis is essential in the follow-up of the transplant patients. Here, we presented a case of renal transplant and Ramsay Hunt syndrome with multiple cranial nerve involvement, with an atypical course. Management and differential diagnosis of this particular case are discussed with a review of the literature. © Başkent University 2011.


PubMed | Bezmialem Foundation University and Haydarpasa Research and Training Hospital
Type: Journal Article | Journal: JSLS : Journal of the Society of Laparoendoscopic Surgeons | Year: 2014

In this study, we evaluated the safety and efficacy of using the LigaSure sealing system (Valleylab, Boulder, Colorado) for laparoscopic decortication of symptomatic hilar renal cysts.Seventeen patients underwent laparoscopic decortication of hilar renal cysts with the LigaSure system. Our study included only symptomatic, Bosniak type 1, simple and symptomatic renal cysts. The operative route, transperitoneal or retroperitoneal, was planned according to the location confirmed by computed tomography. The patients symptoms were preoperatively and postoperatively evaluated by the Wong-Baker visual pain scale. Operative measures and radiologic outcomes were prospectively evaluated.The mean age of the patients was 56.4 years, and the mean follow-up period was 12.5 months. Preoperative computed tomography showed only a single cyst in 15 patients (88.2%) and showed two separate cysts in 2 cases (11.8%). The cysts were located in the perihilar region close to the vascular structure in all patients. A transperitoneal approach was used in 9 patients, and a retroperitoneal approach was used in 8 patients. The mean operative time and hospitalization time were 56.4 minutes and 1.2 days, respectively. Minor complications were observed in 3 patients. Symptomatic and radiologic success rates of 94.2% and 100%, respectively, were achieved.Laparoscopic decortication of symptomatic hilar renal cysts--first reported in the literature in this study--using the LigaSure sealing system is feasible, effective, and safe, even if the cyst is located in the perihilar area.


PubMed | Siyami Ersek Heart and Research Hospital, Kartal Research and Training Hospital, Kosuyolu Heart and Research Hospital, Maltepe University and Haydarpasa Research and Training Hospital
Type: Journal Article | Journal: The journal of sexual medicine | Year: 2016

Vasculogenic erectile dysfunction is a harbinger of vascular disease. Comprehensive cardiac workup is accepted to be beneficial in men with this condition, especially those with otherwise unrecognized cardiovascular disease. We aimed to evaluate the role of two-dimensional speckle-tracking echocardiography (2D-STE) for noninvasive evaluation in patients with documented arteriogenic erectile dysfunction.64 consecutive men with Doppler proven erectile dysfunction of more than 3 months of duration wererecruited. Patients divided into 2 groups according to mean peak systolic velocity (PSV). Patients with PSV <20 cm/sn constituted Group 1 and patients with PSV 20 cm/sn constituted Group 2. All underwent echocardiography and were compared. According to the 2D-STE analysis for the left atrium (LA); strain during ventricular systole (LARes), during late diastole (LA-Pump), strain rate during ventricular contraction (LA-SRs), during passive ventricular filling (LA-SRe), during active atrial contraction (LASRa) values and for LV; global longitudinal strain (GLS), strain rate in systole (GSRs), strain rate in early diastole (GSRe), and strain rate in late diastole (GSRa) values were obtained.Beside diastolic parameters, LA-Res and LA-Pump were found to be significantly different between groups. GLS and GSR values were lower in Group 1. Moreover, correlation analysis revealed a significant correlation of GLS values with PSV (r=-0.4, P= .001).Myocardial deformation parameters by 2D-STE are valuable for detection of subclinical cardiovascular dysfunction in men with arteriogenic erectile dysfunction. This noninvasive method may be used as an emerging prognostic marker for risk stratification.


PubMed | Haydarpasa Research and Training Hospital
Type: Comparative Study | Journal: Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation | Year: 2014

The mammalian target of rapamycin inhibitors sirolimus and everolimus are immunosuppressive drugs for kidney transplant patients, but adverse events may include proteinuria. The purpose of this study was to compare the effects of sirolimus and everolimus on creatinine clearance and proteinuria after kidney transplant.This study was a prospective evaluation period of 50 patients (age, 16-65 y) who had kidney transplant. There were 25 patients who used sirolimus and 25 patients who used everolimus. Evaluation at the beginning mTOR and end of the evaluation period included complete blood count, blood pressure, serum creatinine level, creatinine clearance, and proteinuria level in a 24-hour urine collection.Mean creatinine clearance at the beginning and end of the evaluation period was significantly less in the everolimus than sirolimus group. There was no significant change in creatinine clearance from the beginning to end of the evaluation period in either the sirolimus or everolimus group. Mean proteinuria at the beginning and end of the evaluation period was similar between the sirolimus and everolimus groups. Both groups had a significant increase in mean proteinuria from beginning to end of the evaluation period, but the increase in proteinuria was similar for the sirolimus and everolimus groups (difference not significant).In kidney transplant recipients, sirolimus and everolimus are associated with a similar level of increased mean proteinuria.


PubMed | Yeditepe University and Haydarpasa Research and Training Hospital
Type: Review | Journal: Turkish journal of ophthalmology | Year: 2016

Pregnancy causes significant changes in all systems of the body. Although most of them are physiological, they may also lead to pathological consequences. The resulting pathological changes may occur for the first time or existing diseases affected by pregnancy can become more serious or change course. Diseases specific only to pregnancy may arise. Like all systems of the body, the visual system is also affected by pregnancy, developing a wide range of physiological and pathological changes. Knowing the ocular physiological changes and diagnosing eye diseases that may develop during pregnancy, and preventing and treating these diseases is crucial to ensure the babys healthy development. Therefore, we have reviewed the conditions that an ophthalmologist should recognize, follow-up, and pay attention to during treatment and summarized them under the topic pregnancy and the eye.

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