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Kreis M.K.F.,Glasgow Caledonian University | Cooke D.J.,Glasgow Caledonian University | Cooke D.J.,University of Bergen | Michie C.,Glasgow Caledonian University | And 2 more authors.
Journal of Personality Disorders | Year: 2012

The Comprehensive Assessment of Psychopathic Personality (CAPP; Cooke, Hart, Logan, & Michie, 2004) is a new personality-based model and clinical assessment of psychopathy. This study was the frst to examine the content validity of the English-language CAPP. Content validation is a crucial part of the development and refnement of any new instrument. Prototypical analysis was used to evaluate the representativeness of CAPP symptoms to the psychopathy construct in adults. Symptoms were rated by international mental health professionals (N = 132). Findings support good content validity of the CAPP, with most symptoms rated as highly representative of psychopathy. Domains relating to interpersonal style were particularly prototypical. Confrmatory factor analyses further suggested that CAPP domains are highly unidimensional. However, some CAPP symptoms may be weaker items in the model and further refnement is needed. © 2012 The Guilford Press. Source


Espehaug B.,Haukeland University Hospital
Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række | Year: 2011

Since information on regional variation in the frequency of primary total hip arthroplasty in Norway is scarce, we studied differences by county and regional health authority throughout the last 20 years. We included 112, 514 primary total hip arthroplasties reported to the Norwegian Arthroplasty Register in the years 1989-2008. Annual gender and age standardized frequencies were calculated, and Poisson regression was used for group comparisons (RR = rate ratio). We observed an increase in hip arthroplasty frequency from 109 operations per 100, 000 inhabitants in the years 1991-1995 to 140 in 2006-2008 (RR = 1.28), and more so for operations performed due to coxarthrosis (RR = 1.46). An increased frequency over time was evident in all five regions and 19 counties. Differences between counties and regions had decreased throughout the study period. In the years 2006-2008, Helse Midt (152 operations) had a statistically significant higher frequency than the other regions except for Helse Sør. The lowest frequencies at county level were found for Finnmark (116 operations) and the highest for Aust-Agder (172). While regional differences have decreased since the early 1990 s, existing differences may in part be due to differing access to surgery, varying indications for surgery, or possibly also genetic or cultural differences. Source


Vie T.L.,Helse Forde HF Forde Health Trust | Hufthammer K.O.,Haukeland University Hospital | Holmen T.L.,Norwegian University of Science and Technology | Meland E.,University of Bergen | Breidablik H.J.,Helse Forde HF
Social Science and Medicine | Year: 2014

Self-rated health (SRH) is a widely used health indicator predicting morbidity and mortality in a wide range of populations. However, little is known about the stability and biological basis of SRH. The aim of this study was to map the stability of SRH from adolescence to early adulthood, and to examine the relationships between SRH and biological dysregulation, in terms of allostatic load (AL). The AL score comprises the eleven biomarkers systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), cholesterol, high-density lipoprotein cholesterol (HDL), triglycerides, waist-hip ratio (WHR), diabetes risk profile, glucose, C-reactive protein (CRP) and body mass index (BMI). Eleven years prospective data from the Nord-Trøndelag Health Study (HUNT), Norway, were utilised. Baseline data were gathered from 9141 adolescents (mean age 15.9 years) in the Young-HUNT I survey (1995-1997) and follow-up data were gathered from the adult HUNT3 survey (2006-2008). Altogether, 1906 respondents completed both questionnaires and clinical measurements in both studies. Cross-tables for SRH at baseline and follow-up showed that SRH remained unchanged in 57% of the respondents. Only 3% of the respondents changed their ratings by two steps or more on a four-level scale. Further, linear regression analyses adjusted for age and gender revealed that SRH in adolescence predicted AL in young adulthood. Similar patterns were found for most of the individual biomarkers. The consistency found in SRH from adolescence to young adulthood, and its association with AL across time, indicate that routines for dealing with SRH early in life may be a central strategy to prevent morbidity in the adult population. © 2014 Elsevier Ltd. Source


Zeleke Z.K.,University of Bergen | Moen B.E.,University of Bergen | Moen B.E.,Haukeland University Hospital | Bratveit M.,University of Bergen
BMC Pulmonary Medicine | Year: 2011

Background: There are only a few follow-up studies of respiratory function among cement workers. The main aims of this study were to measure total dust exposure, to examine chronic respiratory symptoms and changes in lung function among cement factory workers and controls that were followed for one year.Methods: The study was conducted in two cement factories in Ethiopia. Totally, 262 personal measurements of total dust among 105 randomly selected workers were performed. Samples of total dust were collected on 37-mm cellulose acetate filters placed in closed faced Millipore-cassettes. Totally 127 workers; 56 cleaners, 44 cement production workers and 27 controls were randomly selected from two factories and examined for lung function and interviewed for chronic respiratory symptoms in 2009. Of these, 91 workers; 38 cement cleaners (mean age 32 years), 33 cement production workers (36 years) and 20 controls (38 years) were examined with the same measurements in 2010.Results: Total geometric mean dust exposure among cleaners was 432 mg/m 3. The fraction of samples exceeding the Threshold Limit Value (TLV) of 10 mg/m 3for the cleaners varied from 84-97% in the four departments. The levels were considerably lower among the production workers (GM = 8.2 mg/m 3), but still 48% exceeded 10 mg/m 3.The prevalence of all the chronic respiratory symptoms among both cleaners and production workers was significantly higher than among the controls.Forced Expiratory Volume in one second (FEV 1) and FEV 1/Forced Vital Capacity (FEV 1/FVC) were significantly reduced from 2009 to 2010 among the cleaners (p < 0.002 and p < 0.004, respectively) and production workers (p < 0.05 and p < 0.02, respectively), but not among the controls.Conclusions: The high prevalence of chronic respiratory symptoms and reduction in lung function is probably associated with high cement dust exposure. Preventive measures are needed to reduce the dust exposure. © 2011 Zeleke et al; licensee BioMed Central Ltd. Source


Strand T.-E.,Cancer Registry of Norway | Rostad H.,Cancer Registry of Norway | Wentzel-Larsen T.,Haukeland University Hospital | Von Plessen C.,University of Bergen
European Respiratory Journal | Year: 2010

Our study describes the new seventh edition of the TNM system for lung cancer in a national population and its clinical implications. We classified 1,885 operated patients with lung cancer, reported to the Cancer Registry of Norway (Oslo, Norway) from 2001 to 2005, according to the sixth and the seventh edition of the TNM system. We compared survival differences adjusting for known prognostic factors. Furthermore, we evaluated the overall predictive ability of both editions using Harrell's concordance index. Survival curves by stage for each of the editions were similar; however, a better description of stage IIIB was observed in the seventh edition. Survival rates of T1b and T2a tumours were similar (log rank p=0.94). The concordance index was 0.68 for both editions, indicating no overall difference in their predictive accuracy. In the seventh edition, 211 (29%) stage IB patients migrated to stage II and 161 (48%) patients migrated from stage IIB to IIA. Stage migrations could change the treatment for up to 326 (17.3%) of the study patients. The seventh edition did not improve the overall predictive ability of the TNM system; however, the new classification implies changes in treatment for nearly one-fifth of the cases. The implications of the seventh TNM edition for the outcomes of patients should be studied further. Copyright©ERS 2010. Source

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