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Box Elder, IN, United States

Hanover College is a private liberal arts college, located in Hanover, in the U.S. state of Indiana, near the banks of the Ohio River. The college is affiliated with the Presbyterian Church. Founded in 1827 by the Rev. John Finley Crowe, it is the oldest private college in Indiana. The Hanover athletic teams participate in the Heartland Collegiate Athletic Conference. Graduates of Hanover are known as Hanoverians. Wikipedia.

Iten H.V.,Hanover College | Iten H.V.,Cincinnati Museum Center | Leme J.D.M.,University of Sao Paulo | Marques A.C.,University of Sao Paulo | Simoes M.G.,Sao Paulo State University
Acta Palaeontologica Polonica | Year: 2013

In a letter to Nature (February, 2011), Xunlai Yuan and collaborators recorded carbon compression fossils from black shales of the Lantian Formation (Ediacaran), southern Anhui Province, South China. The new fossils, described under five morphological types (Types A to E), exhibit degrees of morphological differentiation suggesting that they were multicellular eukaryotes. Some of the Lantian macrofossils were interpreted as algae, but others are of unknown affinities. For reasons noted in this discussion, Type A fossils attracted our particular attention, and we suggest an alternative interpretation of their affinities. According to our view, some of them (at least those with three faces and no globose holdfast at their base) may represent conulariid cnidarians or close medusozoan relatives. The undistorted organism probably was a three-sided cone in life. We believe that our suggested alternative interpretations of the anatomy and affinities of the fossils in question can be useful in guiding future research on the oldest currently known fossil assemblage of multicellular organisms. Copyright © 2012.

Bowers R.M.,University of Colorado at Boulder | McLetchie S.,Hanover College | Knight R.,University of Colorado at Boulder | Knight R.,Howard Hughes Medical Institute | Fierer N.,University of Colorado at Boulder
ISME Journal | Year: 2011

Although bacteria are ubiquitous in the near-surface atmosphere and they can have important effects on human health, airborne bacteria have received relatively little attention and their spatial dynamics remain poorly understood. Owing to differences in meteorological conditions and the potential sources of airborne bacteria, we would expect the atmosphere over different land-use types to harbor distinct bacterial communities. To test this hypothesis, we sampled the near-surface atmosphere above three distinct land-use types (agricultural fields, suburban areas and forests) across northern Colorado, USA, sampling five sites per land-use type. Microbial abundances were stable across land-use types, with ∼ 105-106 bacterial cells per m 3 of air, but the concentrations of biological ice nuclei, determined using a droplet freezing assay, were on average two and eight times higher in samples from agricultural areas than in the other two land-use types. Likewise, the composition of the airborne bacterial communities, assessed via bar-coded pyrosequencing, was significantly related to land-use type and these differences were likely driven by shifts in the sources of bacteria to the atmosphere across the land-uses, not local meteorological conditions. A meta-analysis of previously published data shows that atmospheric bacterial communities differ from those in potential source environments (leaf surfaces and soils), and we demonstrate that we may be able to use this information to determine the relative inputs of bacteria from these source environments to the atmosphere. This work furthers our understanding of bacterial diversity in the atmosphere, the terrestrial controls on this diversity and potential approaches for source tracking of airborne bacteria. © 2011 International Society for Microbial Ecology All rights reserved.

Campbell E.L.,Aurora University | Bruyninckx W.J.,Hanover College | Kelly C.J.,Aurora University | Glover L.E.,Aurora University | And 16 more authors.
Immunity | Year: 2014

Acute intestinal inflammation involves early accumulation of neutrophils (PMNs) followed by either resolution or progression to chronic inflammation. Based on recent evidence that mucosal metabolism influences disease outcomes, we hypothesized that transmigrating PMNs influence the transcriptional profile of the surrounding mucosa. Microarray studies revealed a cohort of hypoxia-responsive genes regulated by PMN-epithelial crosstalk. Transmigrating PMNs rapidly depleted microenvironmental O2 sufficiently to stabilize intestinal epithelial cell hypoxia-inducible factor (HIF). By utilizing HIF reporter mice in an acute colitis model, we investigated the relative contribution of PMNs and the respiratory burst to "inflammatory hypoxia" invivo. CGD mice, lacking a respiratory burst, developed accentuated colitis compared to control, with exaggerated PMN infiltration and diminished inflammatory hypoxia. Finally, pharmacological HIF stabilization within the mucosa protected CGD mice from severe colitis. In conclusion, transcriptional imprinting by infiltrating neutrophils modulates the host response to inflammation, via localized O2 depletion, resulting in microenvironmental hypoxia and effective inflammatory resolution. © 2014 Elsevier Inc.

Tsang P.P.,Dartmouth College | Au M.H.,University of Wollongong | Kapadia A.,Indiana University Bloomington | Smith S.W.,Hanover College
ACM Transactions on Information and System Security | Year: 2010

Several credential systems have been proposed in which users can authenticate to service providers anonymously. Since anonymity can give users the license to misbehave, some variants allow the selective deanonymization (or linking) of misbehaving users upon a complaint to a Trusted Third Party (TTP). The ability of the TTP to revoke a user's privacy at any time, however, is too strong a punishment for misbehavior. To limit the scope of deanonymization, some systems have been proposed in which users can be deanonymized only if they authenticate "too many times," such as "double spending" with electronic cash. While useful in some applications, such techniques cannot be generalized to more subjective definitions of misbehavior, for example, using such schemes it is not possible to block anonymous users who "deface too many Web pages" on a Web site. We present BLAC, the first anonymous credential system in which service providers can revoke the credentials of misbehaving users without relying on a TTP. Since revoked users remain anonymous, misbehaviors can be judged subjectively without users fearing arbitrary deanonymization by a TTP. Additionally, our construction supports a d-strikes-out revocation policy, whereby users who have been subjectively judged to have repeatedly misbehaved at least d times are revoked from the system. Thus, for the first time, it is indeed possible to block anonymous users who have "defaced too many Web pages" using our scheme. © 2010 ACM.

Torresani L.,Hanover College | Szummer M.,Microsoft | Fitzgibbon A.,Microsoft
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2010

We introduce a new descriptor for images which allows the construction of efficient and compact classifiers with good accuracy on object category recognition. The descriptor is the output of a large number of weakly trained object category classifiers on the image. The trained categories are selected from an ontology of visual concepts, but the intention is not to encode an explicit decomposition of the scene. Rather, we accept that existing object category classifiers often encode not the category per se but ancillary image characteristics; and that these ancillary characteristics can combine to represent visual classes unrelated to the constituent categories' semantic meanings. The advantage of this descriptor is that it allows object-category queries to be made against image databases using efficient classifiers (efficient at test time) such as linear support vector machines, and allows these queries to be for novel categories. Even when the representation is reduced to 200 bytes per image, classification accuracy on object category recognition is comparable with the state of the art (36% versus 42%), but at orders of magnitude lower computational cost. © 2010 Springer-Verlag.

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