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Qui Nhon, Vietnam

Hanoi University of Agriculture is an education and research university specializing for agricultural sector. The university is located in Trau Quy town, Gia Lam district, a Hanoi suburban area, about 12 km far from Hanoi city centre. Wikipedia.

Nguyen D.T.,University of science | Le T.H.,University of science | Bui T.T.T.,Hanoi University of Agriculture
European Journal of Medicinal Chemistry | Year: 2013

Reaction of N-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl) thiosemicarbazide and different substituted benzaldehydes gave some new substituted benzaldehyde N-(2,3,4,6-tetra-O-acetyl-β-d-galactopyranosyl) thiosemicarbazones. The reaction was performed using conventional and microwave-assisted heating methods. The structures of thiosemicarbazones were confirmed by spectroscopic (IR, 1H NMR, 13C NMR and ESI-MS) method. The antioxidant activity of these thiosemicarbazones was evaluated in vitro and in vivo, and it's shown that some of these compounds had significant antioxidant activity. Amongst the compounds screened for antioxidant activity, thiosemicarbazones 4a, 4b and 4c showed good antioxidant activity on DPPH. The compounds 4g, 4i, 4l caused significant elevation of SOD activity and 4e, 4g, 4i, 4l had higher catalase activity, and only compounds 4c and 4f expressed the GSH-Px activity. Source

Huy G.D.,East China University of Science and Technology | Huy G.D.,Hanoi University of Agriculture | Zhang M.,East China University of Science and Technology | Zuo P.,East China University of Science and Technology | Ye B.-C.,East China University of Science and Technology
Analyst | Year: 2011

A colorimetric assay has been developed for the simultaneous selective detection of silver(i) and mercury(ii) ions utilizing metal nanoparticles (NPs) as sensing element based on their unique surface plasmon resonance properties. In this method, sulfhydryl group modified cytosine-(C)-rich ssDNA (SH-C-ssDNA) was self-assembled on gold nanoparticles (AuNPs) to produce the AuNPs-C-ssDNA complex, and sulfhydryl group modified thymine-(T)-rich ssDNA (SH-T-ssDNA) was self-assembled on silver nanoparticles (AgNPs) to produce the AgNPs-T-ssDNA complex. Oligonucleotides (SH-C-ssDNA or SH-T-ssDNA) could enhance the AuNPs or AgNPs against salt-induced aggregation. However, the presence of silver(i) ions (Ag +) in the complex of ssDNA-AuNPs would reduce the stability of AuNPs due to the formation of Ag + mediated C-Ag +-C base pairs accompanied with the AuNPs color change from red to purple or even to dark blue. Moreover, the presence of mercury(ii) ions (Hg 2+) would also reduce the stability of AgNPs due to the formation of Hg 2+ mediated T-Hg 2+-T base pairs accompanied with the AgNPs color change from yellow to brown, then to dark purple. The presence of both Ag + and Hg 2+ will reduce the stability of both AuNPs and AgNPs and cause the visible color change. As a result, Ag + and Hg 2+ could be detected qualitatively and quantitatively by the naked eye or by UV-vis spectral measurement. The lowest detectable concentration of a 5 nM mixture of Ag + and Hg 2+ in the river water was gotten by the UV-vis spectral measurement. © 2011 The Royal Society of Chemistry. Source

Kuklik V.,Czech University of Life Sciences | Hoang T.D.,Hanoi University of Agriculture
Agricultural Water Management | Year: 2014

The main objective of this paper is determination of principal relationships influencing the distribution of moisture content in a soil profile under an emitter in point irrigation. Research was carried out by conducting field experiments. They determined geometry of wetted soil volume in a soil profile under point irrigation. Infiltration of water from a single emitter and the resulting spatial distribution is a typical feature of localized irrigation technology. The field experiments using different emitter discharges and various periods of irrigation on haplic Luvisol (ha LV) (ALFISOLS Udalfs) on loess were conducted in a soil profile 1. m deep.Admissible duration of irrigation in relation to discharge rates has been calculated and illustrated in a graph. Incorrect irrigation practices can cause serious environmental damage. A method for determining the width and depth of the wetted soil volume under the point irrigation was developed. This method is rapid and simple, and it gives consistent results. © 2013 Elsevier B.V. Source

Tran D.T.,Catholic University of Leuven | Tran D.T.,Hanoi University of Agriculture | Knez K.,Catholic University of Leuven | Janssen K.P.,Catholic University of Leuven | And 4 more authors.
Biosensors and Bioelectronics | Year: 2013

The rising prevalence to food allergies in the past two decades, together with the fact that the only existing therapy is avoidance of allergen-containing food next to the implementation of anti-allergic drugs, urges the need for improved performance of current assays to detect potential allergens in food products. Therein, the focus has been on aptamer-based biosensors in recent years. In this paper we report for the first time the selection of aptamers against one of the most important peanut allergens, Ara h 1. Several Ara h1 DNA aptamers were selected after eight selection rounds using capillary electrophoresis (CE)-SELEX. The selected aptamers specifically recognized Ara h 1 and did not significantly bind with other proteins, including another peanut allergen Ara h 2. The dissociation constant of a best performing aptamer was in the nanomolar range as determined independently by three different approaches, which are surface plasmon resonance, fluorescence anisotropy, and capillary electrophoresis (353±82. nM, 419±63. nM, and 450±60. nM, respectively). Furthermore, the selected aptamer was used for bioassay development on a home-built fiber optic surface plasmon resonance (FO-SPR) biosensor platform for detecting Ara h 1 protein in both buffer and food matrix samples demonstrating its real potential for the development of novel, more accurate aptamer-based biosensors. In conclusion, the reported aptamer holds a great potential for the detection of Ara h 1 in both the medical field and the food sector due to its high affinity and specificity for the target protein. © 2012 Elsevier B.V. Source

Kararigas G.,Charite University Hospital | Nguyen B.T.,Goettingen University Hospital | Nguyen B.T.,Hanoi University of Agriculture | Jarry H.,Goettingen University Hospital
Molecular and Cellular Endocrinology | Year: 2014

The modulation of cardiac growth by estrogen in healthy mice is not completely understood. The aim was to investigate the effects of estrogen on cardiac growth in healthy mice lacking either estrogen receptor (ER) α or β. Wild-type (WT), ERα knockout (ERKO) and ERβ knockout (BERKO) 2-month-old mice were ovariectomized and randomly assigned to groups receiving an estradiol (E2)-containing or soy-free (control, CON) diet ( n= 5-7/group). After three months of E2 administration, WT and BERKO mice had significantly lower body weight, higher relative uterus and heart weight than CON mice, while there was no major E2 effect in ERKO mice. Furthermore, there was a higher concentration of E2-responsive genes Igf1 and Myocd in WT and BERKO but not in ERKO mice. Together, these findings indicate that the estrogenic regulation of cardiac growth in healthy mice is primarily mediated through ERα and not ERβ. © 2013 Elsevier Ireland Ltd. Source

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