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Tang B.-C.,Hangzhou Huishun Biological Technology Co. | Tong Y.-G.,Hangzhou Huishun Biological Technology Co. | Pan W.-C.,Hangzhou Huishun Biological Technology Co. | Yang Z.-Q.,Hangzhou Huishun Biological Technology Co. | And 2 more authors.
Xiandai Huagong/Modern Chemical Industry

A kind of extraction technology of heparinoid from waste protein generated in the heparin extraction process is proposed. With the total unit number of heparinoid as the assessment index, the optimum conditions for the adsorption process are determined by single factor and orthogonal design experiments as follows: 55℃ of the temperature, 0.8 mol/L of the salt concentration and 8.72 of pH value. Besides that, the optimum conditions for the oxidation process are also shown as follows: 2: 100 of the volume ratio of hydrogen peroxide and 6 hours of the reaction time. Compared to the traditional processing method for waste protein, the economic value is efficiently improved. It provides a good reference for the heparin production enterprises. © 2015, China National Chemical Information Center. All right reserved. Source

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