Bonaduz, Switzerland
Bonaduz, Switzerland

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Patent
Hamilton Bonaduz Ag | Date: 2014-04-08

A scale and related method for a length-measuring system for recording the absolute values of angles or distances. The scale includes a printed circuit board, at least one track for identifying length information or angle information and a coding for identifying the scale. The coding has at least one coding element comprising at least two electrodes and a conductive connection between the electrodes on an insulator substrate. The electrical connection is configured to be irreversibly destroyed when an electrical current is applied.


Patent
Hamilton Bonaduz Ag | Date: 2014-03-31

A sample dispenser for an analysis device, in particular for an analysis device working according to the principle of liquid chromatography, in particular high pressure liquid chromatography, or gas chromatography, comprising a sample intake for receiving a sample to be analyzed, an inlet through which an eluent can be supplied, an outlet, and an injection valve arrangement, which can be switched at least from an intake position to an injection position, wherein, at least in the intake position and in the injection position, the inlet is in fluid connection with the outlet to deliver the eluentif applicable, having the sample added theretoat least partly to the outlet, wherein, in the intake position, the sample intake is separated from the eluent in a fluid-tight manner, and wherein, in the injection position, the sample in the sample intake can combine with the eluent, wherein the sample dispenser is configured as a disposable component.


Patent
Hamilton Bonaduz Ag | Date: 2014-12-15

A sample manipulation device, in particular for removing lids from sample containers and/or for placing lids onto sample containers, comprising a sample unit and a manipulation unit having at least one manipulation tool; wherein the sample unit and the manipulation unit are movable relative to each other along a movement direction; wherein the sample unit comprises a sample carrier receptacle for receiving at least one sample carrier for holding one or more sample containers, said sample carrier extending in a longitudinal direction and a transverse direction orthogonal to said longitudinal direction; wherein the sample unit furthermore is transferable between a first orientation in which the longitudinal direction of a sample carrier received in the sample carrier receptacle is parallel to the movement direction between sample unit and manipulation unit, and a second orientation in which the transverse direction of a sample carrier received in the sample carrier receptacle is parallel to the movement direction between sample unit and manipulation unit.


The present invention relates to a coupling formation of a pipetting channel of a pipetting device for coupling of an implement, for instance a pipette tip, or a laboratory instrument, laboratory tool or the like, thereto, wherein the coupling formation surrounds a pipetting channel section which extends along a pipetting channel axis which defines an axial direction, wherein the coupling formation additionally has, at its free longitudinal end, a pressure-imparting orifice into which the pipetting channel section opens and has, at its radially outer surface which surrounds the pipetting channel axis and extends principally in axial direction and in peripheral direction about the pipetting channel axis relative to the pipetting channel axis, a coupling projection which yields in the radial direction, which is characterized in that the coupling projection is provided so as to be essentially undeformable but radially movable on a spring arrangement which is elastic in radial direction.


Patent
Hamilton Bonaduz Ag | Date: 2014-01-08

The invention concerns a sample handling system and a process for the handling of chemical or biological samples, particularly body fluids such as blood, saliva, secretions, etc. or tissue samples, and more specifically for the processing of samples for DNA analysis by means of PCR, comprising a dosing device with a receiving plate (12), with the receiving plate (12) being configured in an essentially horizontal position in a plane defined by a first and a second axis (X, Y); having at least one working arm (14, 16, 18) that is movable in the direction of the first axis (X) relative to the receiving plate (12), preferably along a first edge (13) of the receiving plate (12), and wherein the working arm (14, 16, 18) extends along the second axis (Y) above the receiving plate (12), at least one pipetting mechanism (30) that is movable in the direction of the second axis (Y) is mounted on the working arm (14, 16, 18), the pipetting mechanism (30) comprises at least one pipetting channel (32) that is movable in the direction of a third axis (Z) orthogonal to the direction of the first and second axes (X, Y) and has a pipette tip (33) mounted or mountable thereon, and said pipetting mechanism (30) is configured so as to dispense or aspirate liquid into or out of a sample vessel; and at least one thermal cycler (50, 52) provided in the area of the receiving plate (12). According to the invention, the thermal cycler (50, 52) should be configured on the receiving plate (12) in such a way that the pipetting mechanism (30) is movable in a position above the sample vessels in the thermal cycler (50, 52), making a pipetting step possible. Opening/closing of a closing device (54) of the thermal cycler takes place in accordance with the steps of a PCR process, and pipetting of components into sample vessels in the thermal cycler takes place in accordance with the setting of the closing device (54).


Patent
Hamilton Bonaduz Ag | Date: 2014-12-19

The invention relates to a covering device (10), in particular a lid, for covering reaction vessels (50), in particular PCR plates, microtiter plates, and the like, comprising: a substantially flat main body (14) having an inside (34) and an outside (12), at least one planar sealing element (36) arranged on the main body (14) and connected to the main body, wherein the at least one sealing element (36) is arranged on the inside (34) of the main body (14), an edge segment (16), which runs along the periphery of the main body and extends from the outside (12) in the direction of the inside (34) and beyond the inside, and at least one spring element (22, 24) arranged on the main body (14) or on the sealing element (36), which at least one spring element is designed in such a way that the at least one spring element supports the covering device (10) on a surface (54) of a reaction vessel (50) to be covered facing the covering device (10) in the relaxed state of the at least one spring element and that an intermediate space (56) is formed between the sealing element (36) and the surface (54) of the reaction vessel (50).


Patent
HAMILTON Bonaduz AG | Date: 2014-10-29

A cap for cell culture container enclosing a culture volume and having an opening, comprising a valve arrangement, suitable for filling of the cell culture container with a fluid and/or for pumping fluid out from the cell culture container, and a compensation opening suitable for aerating the cell culture container and/or for pressure compensation during filling and pumping out, said valve arrangement being designed to be switchable between an outlet position and a blocking position, to be connectable to a fluid supply interface, and to be switchable without contact.


Patent
Hamilton Bonaduz Ag | Date: 2014-06-06

The invention relates to a syringe, comprising: a syringe body (12) having an axial inner cavity (16), which extends in the direction of a longitudinal axis (LA) of the syringe body (12) and in which a plunger (14) can be or is accommodated in such a way that the plunger can be moved in the longitudinal direction, and a needle (18), which can be or is connected to the syringe body (12) at a longitudinal end of the syringe body (12), wherein the syringe body (12) has a coupling segment (20) at the needle-side longitudinal end of the syringe body (12), to which coupling segment (20) the needle (18) can be or is fastened by means of a connecting element (22) that can be slid on in the longitudinal direction. According to the invention, at least one radially inward cavity (34) is provided on the coupling segment (20), which cavity can be brought into engagement or is in engagement with at least one corresponding locking segment (32) provided on the connecting element (22).


The invention relates to a liquid supply interface (62, 62, 62, 62) for a cell culture system for supplying cell cultures found in different cell culture containers (10, 10, 10) with a nutrient medium, wherein the liquid supply interface (62, 62, 62, 62) comprises: a housing (68) defining a flow area (72); a first connection formation (76) for the liquid-transferring connection of a first fluid line (84) to the housing (68); a second connection formation (78) formed separately from the first for the liquid-transferring connection of a second fluid line (88) to the housing (68); a third connection formation (80) formed separately from the first two for the liquid-transferring connection of the housing (68) to a third fluid line; a coupling formation (64, 66) formed separately from the connection formations (76, 78, 80), which is formed for the producible and detachable liquid-transferring coupling contact according to the operation, with a corresponding counter-coupling formation (38, 40) of a cell culture container (10, 10, 10).


The present invention relates to a linear movement device comprising at least two linear movement units (12, 14) which are guided in a movable manner along a shared linear movement axis (L), wherein the linear movement device (10) comprises a first linear drive (28) and a second linear drive (30), in such a way that each linear movement unit (12, 14) can be driven in movement along the linear movement axis (L) merely by the first linear drive (28), merely by the second linear drive (30), and also by both linear drives (28, 30) together, the first and the second linear drive (28, 30) being coupled to the linear movement units (12, 14) so as to transmit drive force, in such a way that when merely the first linear drive (28) or merely the second linear drive (30) is activated the linear movement units (12, 14) can be driven in movement in a shared direction along the linear movement axis (L) with a speed relative to one another, whereas when the first and the second linear drives (28, 30) are activated simultaneously all of the linear drive units (12, 14) can be driven at least in joint movement in the same direction along the linear movement axis (L) without any speed relative to one another.

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