Hamamatsu, Japan

Hamamatsu University School of Medicine is a national university in Hamamatsu, Shizuoka, Japan, founded in 1974. Wikipedia.


Time filter

Source Type

Patent
Hamamatsu University School of Medicine and Hamamatsu Photonics K K | Date: 2017-03-22

A breast measurement apparatus 1A includes a distance measurement unit 10 measuring a distance from a skin to a light absorption portion for a measurement region of a breast which is a normal region including no tumor or an object region including a tumor, a light measurement unit 15 measuring a hemoglobin amount in the measurement region by a light measurement method using measurement light of a predetermined wavelength, a correlation data storage unit 33 storing normal correlation data of the distance to the light absorption portion and a normal hemoglobin amount generated based on measurement results for normal regions, and an evaluation value calculation unit 35 calculating a property evaluation value of the tumor based on the normal hemoglobin amount, obtained from the normal correlation data and the distance to the light absorption portion in the object region, and an object hemoglobin amount in the object region. This realizes a breast measurement method and a measurement apparatus capable of improving measurement accuracy of a property of a tumor inside a breast.


Patent
Hamamatsu University School of Medicine and Hamamatsu Photonics K K | Date: 2015-03-16

The present invention has an object to measure lymphatic pressure with more safety and ease at lower cost. To achieve this, a lymphatic pressure-measuring system 1 includes: a manchette 11 fitted on a vital observation portion; a measurement unit 13 that measures and outputs pressure of the manchette 11; an infrared camera 21 that detects fluorescence emitted from fluorescent dye previously injected into a lymph vessel in the vital observation portion; and an image processing device 22 that generates and displays an image showing a position of the fluorescent dye in the lymph vessel based on a detection result of the infrared camera 21. The infrared camera 21 repeats the detection while the pressure of the manchette 11 decreases from first pressure to block a lymph flow in the vital observation portion to second pressure at restart of the lymph flow. The measurement unit 13 repeats the measurement during the period.


Patent
ONO Pharmaceutical Co. and Hamamatsu University School of Medicine | Date: 2015-07-08

By intravenously administering a sedative comprising methyl 3-[(4S)-8-bromo-1-methyl-6-(2-pyridinyl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate or a salt thereof to a patient by a dosing regimen including a two-step process disclosed in the present invention, general anesthesia can be safely and promptly induced and maintained.


Ito T.,Hamamatsu University School of Medicine
Clinical and Developmental Immunology | Year: 2013

Alopecia areata is considered to be a cell-mediated autoimmune disease, in which autoreactive cytotoxic T cells recognize melanocyte-associated proteins such as tyrosinase. This review discusses recent advances in the understanding of the pathogenesis of alopecia areata, focusing on immunobiology and hormonal aspects of hair follicles (HFs). The HF is a unique "miniorgan" with its own immune and hormonal microenvironment. The immunosuppressive milieu of the anagen hair bulb modulated by immunosuppressive factors is known as "hair follicle immune privilege." The collapse of the hair follicle immune privilege leads to autoimmune reactions against hair follicle autoantigens. Alopecia areata is sometimes triggered by viral infections such as influenza that causes excess production of interferons (IFN). IFN-γ is one of the key factors that lead to the collapse of immune privilege. This paper reviews the interactions between the endocrine and immune systems and hair follicles in the pathogenesis of alopecia areata. © 2013 Taisuke Ito.


We report the detection of a group of endogenous low molecular weight metabolites (LMWM) in mouse brain (80-500 Da) using TiO(2) nanoparticles (NPs) in nanoparticle-assisted laser desorption/ionization-imaging mass spectrometry (Nano-PALDI-IMS) without any washing and separation step prior to MS analysis. The identification of metabolites using TiO(2) NPs was compared with a conventional organic matrix 2,5-dihydroxybenzoic acid (DHB) where signals of 179 molecules were specific to TiO(2) NPs, 4 were specific to DHB, and 21 were common to both TiO(2) NPs and DHB. The use of TiO(2) NPs enabled the detection of a higher number of LMWM as compared to DHB and gold NPs as a matrix. This approach is a simple, inexpensive, washing, and separation free for imaging and identification of LMWM in mouse brain. We believe that the biochemical information from distinct regions of the brain using a Nano-PALDI-IMS will be helpful in elucidating the imbalances linked with diseases in biomedical samples.


Patent
Hamamatsu University School of Medicine | Date: 2015-01-28

An autism diagnosis support method and system, and autism diagnosis support device capable of providing support to early detection and early definite diagnosis especially to autism of infants, on the basis of objective evaluation, are provided by using a conventionally proposed eye-gaze detection technique. For example, a method for supporting autism diagnosis for a subject, uses an eye-gaze detecting unit (A) at least including a camera portion capturing an image of an eye of the subject, or an electrode portion to be mounted on a head of the subj ect and detecting a movement of the eye, or a display portion to be disposed at a position in an eye gaze direction of the subject. The method includes: displaying, on a screen of the display portion, a combination image for sequentially displaying at least two images including a predetermined human image (I) and a predetermined non-human image (II); and evaluating an eye-gaze position of the subj ect by detecting eye-gaze position information on the subject looking at the combination image in use of the eye-gaze detecting unit, then inputting the eye-gaze position information on the subject in an eye-gaze position information storing portion, and comparing, based on an eye-gaze position evaluation algorithm, the eye-gaze position information on the subject with eye-gaze position information on an individual with autism and/or a typically developing individual.


Patent
Hamamatsu University School of Medicine | Date: 2015-09-18

Provided is a luminous, apparatus such as a display, having a function of preventing attraction of insects. A display apparatus 1 has a light emission surface 1 whose peripheral edge region is at least partially formed as a low-attraction region which is less capable of attracting bugs, wherein the low-attraction region is composed of an optical property gradient region whose at least one optical property gradually changes in a direction from an inward side to an outward side of the light emission surface.


A method is provided for inhibiting proliferation of a high LIX1L-expressing tumor cell, in which the expression or function of a LIX1L gene with respect to a tumor cell highly expressing the LIX1L gene is inhibited.


Patent
Hamamatsu University School of Medicine | Date: 2015-07-29

The present invention relates to an agent for activating mammalian sperm and a method for activating sperm by use of the activating agent. More specifically, the present invention relates to a sperm activating agent containing endo--galactosidase and/or FGF, which accelerate motility of mammalian sperm, for use in in-vitro fertilization and artificial insemination by husband and a sperm activating method by adding endo--galactosidase and/or FGF.


A method is provided for inhibiting proliferation of a high LIX1L-expressing tumor cell, in which the expression or function of a LIX1L gene with respect to a tumor cell highly expressing the LIX1L gene is inhibited.

Loading Hamamatsu University School of Medicine collaborators
Loading Hamamatsu University School of Medicine collaborators