Time filter

Source Type

Tripathi V.,University of the West Indies | Singh R.,Hamad Medical Corporation HMC
BMJ Open | Year: 2017

Background: Indonesia has shown a nominal increase in antenatal care (ANC) coverage from 93% to 96% in the Indonesia Demographic Health Survey (IDHS)-2012. This is high but for a comprehensive assessment of maternal health coverage in Indonesia, safe delivery services need to be assessed in conjunction with ANC coverage. Materials and methods: The study uses survey data from the IDHS-2012 that was conducted among women aged 15-49 years who gave birth during the past 3 years preceding the survey. Socioeconomic and demographic factors affecting ANC coverage and safe delivery services are analysed by segregating the data into 7 regions of Indonesia. Results: Multivariate results show that besides wealth and education differentials, regional differences significantly affect the usage of ANC and safe delivery services across the 7 regions. Univariate analyses show that Sulawesi, Maluku and Western New Guinea islands are at a disadvantage in accessing ANC and safe delivery services. Conclusions: The study recommends that disaggregated regional targets be set in order to further reduce maternal mortality rates in Indonesia.


Abdelhady M.H.,Jahra Hospital | Salama A.F.,Hamad Medical Corporation HMC | Karam M.,Hamad Medical Corporation HMC | Bashah M.,Hamad Medical Corporation HMC
Obesity Surgery | Year: 2017

Background: Laparoscopic sleeve gastrectomy (LSG) is gaining popularity for the treatment of morbid obesity. It is a simple, low-cost procedure resulting in significant weight loss within a short period of time. LSG is a safe procedure with a low complication rate. The most significant complications are staple-line bleeding, stricture, and staple-line leak. Formation of liver and splenic abscesses is an extremely rare consequence of LSG. Liver abscess has been reported in one case report while splenic abscess has been reported in five case reports after LSG. Methods: This study is a case report and literature review. Results: We report two cases of a pyogenic liver abscesses and two cases of splenic abscesses after LSG. Conclusions: As LSG becomes more popular, clinicians need to be aware of uncommon but potentially serious complications related to it. © 2017 Springer Science+Business Media New York


Vozzi D.,Institute for Maternal and Child Health | Morgan A.,University of Trieste | Vuckovic D.,University of Trieste | D'Eustacchio A.,Institute for Maternal and Child Health | And 6 more authors.
Gene | Year: 2014

Deafness is a really common disorder in humans. It can begin at any age with any degree of severity. Hereditary hearing loss is characterized by a vast genetic heterogeneity with more than 140 loci described in humans but only 65 genes so far identified. Families affected by hearing impairment would have real advantages from an early molecular diagnosis that is of primary relevance in genetic counseling. In this perspective, here we report a family-based approach employing Ion Torrent DNA sequencing technology to analyze coding and UTR regions of 96 genes related to hearing function and loss in a first series of 12 families coming from Italy and Qatar. Using this approach we were able to find the causative gene in 4 out of these 12 families (33%). In particular 5 novel alleles were identified in the following genes LOXHD1, TMPRSS3, TECTA and MYO15A already associated with hearing impairment. Our study confirms the usefulness of a targeted sequencing approach despite larger numbers are required for further validation and for defining a molecular epidemiology picture of hearing loss in these two countries. © 2014 Elsevier B.V.


Singh R.,Hamad Medical Corporation HMC | Tripathi V.,University of the West Indies
PeerJ | Year: 2015

Background. India accounts for 24% to all under-five mortality in the world. Residence in rural area, poverty and low levels of mother's education are known confounders of under-five mortality. Since two-thirds of India's population lives in rural areas, mothers employed in agriculture present a particularly vulnerable population in the Indian context and it is imperative that concerns of this sizeable population are addressed in order to achieve MDG4 targets of reducing U5MR to fewer than 41 per 1,000 by 2015. This study was conducted to examine factors associated with under-five mortality among mothers employed in agriculture. Methods. Data was retrieved from National Family Household Survey-3 in India (2008). The study population is comprised of a national representative sample of single children aged 0 to 59 months and born to mothers aged 15 to 49 years employed in agriculture fromall 29 states of India. Univariate andMultivariate Cox PH regression analysis was used to analyse the Hazard Rates of mortality. The predictive power of child mortality among mothers employed in agriculture was assessed by calculating the area under the receiver operating characteristic (ROC) curve. Results. An increase in mothers' ages corresponds with a decrease in child mortality. Breastfeeding reduces child mortality by 70% (HR 0.30, 0.25-0.35, p = 0.001). Standard of Living reduces child mortality by 32% with high standard of living (HR 0.68, 0.52-0.89, 0.001) in comparison to low standard of living. Prenatal care (HR 0.40, 0.34-0.48, p = 0.001) and breastfeeding health nutrition education (HR 0.45, 0.31-0.66, p = 0.001) are associated significant factors for child mortality. Birth Order five is a risk factor for mortality (HR 1.49, 1.05-2.10, p = 0.04) in comparison to Birth Order one among women engaged in agriculture while the household size (6-10 members and ≥11 members) is significant in reducing child mortality in comparison to ≤5 members in the house. Under-five mortality among mothers employed in agriculture in India discriminated well between death and survival (Area Under ROC was 0.75, 95% CI [0.73-0.77]) indicating that the model is good for appropriate prediction of child mortality. Conclusion. In a nationally representative sample of households in India, mother's age, breastfeeding, standard of living, prenatal care and breastfeeding health nutrition education are associated with reduction in child mortality. © 2015 Singh et al.


Tripathi V.,University of the West Indies | Singh R.,Hamad Medical Corporation HMC
PeerJ | Year: 2015

Background. Nepal is set to achieveMDG-5 goals by end of 2015.However, maternal health parameters will remain way below those of developed countries. This study was conducted to assess the factors contributing to utilization of ANC and safe delivery services with the aim of furthering overall maternal health parameters in Nepal. Material and Methods. Using survey data fromthe Nepal Demographic and Health Survey 2011, socio-economic and demographic factors associated with the utilization of ANC and safe delivery services among women aged 15-49 years who gave births during the last three years preceding the survey are examined. Data was segregated into three ecological zones: Mountain, Hill and Terai zones for univariate analyses. Data from all three zones was then pooled for univariate and multivariate logistic regression analyses of Antenatal Care and Safe Delivery services inNepal. Results and Conclusion. The analyses show that rural place of residence is at a disadvantage in receiving ANC (OR, 0.8; 95% CI [0.7-0.9]) and ensuring safe delivery (OR, 0.6; 95% CI [0.5-0.7]).Woman's education, husband's education and wealth quintile are significant factors in ensuring ANC and safe delivery services. Further, the analyses show that Budh/Muslim/Kirat/Christians are at a significant disadvantage in ensuring safe delivery (OR, 0.8; 95% CI [0.7-0.9]) as compared with Hindus. Though ecological zones lost their significance in receiving ANC, women in the Terai region are at a significant advantage in ensuring safe delivery (OR, 1.7; 95% CI [1.2-2.1]). Recommendation. Segregated targets should be set for the different ecological zones for further improvement in maternal mortality rates in Nepal. © 2015 Tripathi and Singh.


Al Suwaidi J.,Hamad Medical Corporation HMC | Ali W.M.,Hamad Medical Corporation HMC | Aleryani S.L.,Vanderbilt University
Clinica Chimica Acta | Year: 2013

This article reviews current knowledge in khat (cathinone) research and its health impacts and toxicity in the cardiac system of khat chewers based on current evidence. The authors describe the process by which khat is postulated to induce multiple cardiac abnormalities by illustrating multiple case reports as described from around the world. The role of free radicals in inducing cardiac disease is also discussed. Future research areas are proposed to enhance our understanding of the mode of action of this toxicological drug. © 2013 Elsevier B.V.


Al Jaber J.,Hamad Medical Corporation HMC
Angiology | Year: 2010

A 51-year old Middle-Eastern man presented with recurrent chest pain associated with ST-segment elevation. The patient was treated with placement of a stent in the right coronary artery. He was subsequently diagnosed with severe hyperthyroidism secondary to Graves disease, which is thought to be the cause of the coronary spasm. The patient was treated with neomercazole and potassium iodide solution, and diltiazem, and nitrates with resolution of his symptoms. This unusual case highlights the importance of considering hyperthyroidism in the differential diagnosis of recurrent chest pain and coronary artery spasm. We suggest routine thyroid function testing in patients with coronary spasm.


Suwaidi J.A.,Hamad Medical Corporation HMC | Asaad N.,Hamad Medical Corporation HMC | Al-Qahtani A.,Hamad Medical Corporation HMC | Al-Mulla A.W.,Hamad Medical Corporation HMC | And 2 more authors.
Acute Cardiac Care | Year: 2012

Introduction: The clinical characteristics and outcome of patients hospitalized with heart failure vary according to ethnicities. Background: Limited epidemiologic data are available about the clinical characteristics and outcome of heart failure (HF) patients among non-Caucasian populations. Methods: Between 1 January 1991 and 31 December 2010; 41 453 consecutive patients were hospitalized at Hamad General Hospital, Doha, Qatar for cardiac reasons. Patients were into two groups; hospitalized with HF (n =7069) and hospitalized for non-HF (no-HF). Among HF patients Sub-analysis was made according to ethnicity; Middle-eastern Arabs (MEA) (n =5227) versus South Asian (SA) (n =1289) patients. Results: HF patients were older and more likely to be female when compared to non-HF patients. HF patients were also more likely to have diabetes mellitus (DM), hypertension (HTN), atrial fibrillation (AF) and renal impairment when compared to non-HF patients. SA HF patients younger and less likely to have DM, HTN and AF when compared to MEA patients. Over the 20-years period there was decrease in in-hospital mortality and stroke rates regardless of ethnicity (death; 8.3% to 4.8%, stroke; 0.8% to 0.1%; all P =0.001).Conclusion: HF patients in the Middle East present at relatively younger age regardless of ethnicity. In-hospital mortality and stroke rates decreased significantly over the 20-years. © 2012 Informa UK, Ltd.


Al Suwaidi J.,Hamad Medical Corporation HMC
Current Cardiovascular Risk Reports | Year: 2016

Data about cardiovascular risk factors among Americans of Arab descent (AA) is limited. This article aims to provide an up-to-date review of cardiovascular risk factors and diseases among AA living in the United States (US). We summarize the limited existing data about the prevalence of the various cardiovascular risk factors and diseases among AA and compare that to Arabs living in Arab countries. We also outline challenges of conducting cardiovascular research among AA. In conclusion there is paucity of data about cardiovascular risk factors and diseases among AA. The current study suggests the urgent need for better ways to identify AA in the US and the development of large prospective studies on determinants of cardiovascular health including potential factors such as acculturation. © 2016, Springer Science+Business Media New York.


Ahmed E.,Hamad Medical Corporation HMC | El-Menyar A.,Hamad Medical Corporation HMC | Singh R.,Hamad Medical Corporation HMC | Al Binali H.A.,Hamad Medical Corporation HMC | Al Suwaidi J.,Hamad Medical Corporation HMC
Open Cardiovascular Medicine Journal | Year: 2012

Introduction: Despite the fact that the elderly constitute an increasingly important group of patients with acute coronary syndrome (ACS), they are often excluded from clinical trials and are underrepresented in clinical registries. Aims: To evaluate the impact of age in patients hospitalized with ACS. Methods: Data collected for all patients presenting with ACS (n=16,744) who were admitted in Qatar during the period (1991-2010) and were analyzed according to age into 3 groups (≤50 years [41.4%], 51-70 years [48.7%] and >70 years [9.8%]). Results: Older patients were more likely to be women and have hypertension, diabetes mellitus, and renal failure, while younger patients were more likely to be smokers. Non-ST-elevation myocardial infarction and heart failure were more prevalent in older patients. Older age was associated with undertreatment with evidence-based therapies and had higher mortality rate. Age was independent predictor for mortality. Over the study period, the relative reduction in mortality rates was higher in the younger compared with the older patients (61, 45.9 and 35.5%). Conclusions: Despite being a higher-risk group, older patients were undertreated with evidence based therapy and had worse short-term outcome. Guidelines adherence and improvement in hospital care for elderly patients with ACS may potentially reduce morbidity and mortality. © Ahmed et al.

Loading Hamad Medical Corporation HMC collaborators
Loading Hamad Medical Corporation HMC collaborators