Istanbul, Turkey
Istanbul, Turkey

Haliç University is a foundation university, which was founded in 1998 by the Children Leukemia Foundation in Turkey.Haliç University offers 21 academic departments in its five faculties, with three schools, School of Nursing, School of Physical Education and Sport and School of Health science and Conservatory. Wikipedia.

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Ozekes S.,Istanbul Commerce University | Osman O.,Halic University
Journal of Medical Systems | Year: 2010

In this paper, a Computer Aided Detection (CAD) system based on three-dimensional (3D) feature extraction is introduced to detect lung nodules. First, eight directional search was applied in order to extract regions of interests (ROIs). Then, 3D feature extraction was performed which includes 3D connected component labeling, straightness calculation, thickness calculation, determining the middle slice, vertical and horizontal widths calculation, regularity calculation, and calculation of vertical and horizontal black pixel ratios. To make a decision for each ROI, feed forward neural networks (NN), support vector machines (SVM), naïve Bayes (NB) and logistic regression (LR) methods were used. These methods were trained and tested via k-fold cross validation, and results were compared. To test the performance of the proposed system, 11 cases, which were taken from Lung Image Database Consortium (LIDC) dataset, were used. ROC curves were given for all methods and 100% detection sensitivity was reached except naïve Bayes. © Springer Science + Business Media, LLC 2008.

Yumrutas R.,University of Gaziantep | Unsal M.,Halic University
Solar Energy | Year: 2012

An analytical model is presented and analyzed to predict the long term performance of a solar assisted house heating system with a heat pump and an underground spherical thermal energy storage tank. The system under investigation consists of a house, a heat pump, solar collectors and a storage tank. The present analytical model is based on a proper coupling of the individual energy models for the house, the heat pump, useful solar energy gain, and the transient heat transfer problem for the thermal energy storage tank. The transient heat transfer problem outside the energy storage tank is solved using a similarity transformation and Duhamel's superposition principle. A computer code based on the present model is used to compute the performance parameters for the system under investigation. Results from the present study indicate that an operational time span of 5-7. years will be necessary before the system under investigation can attain an annually periodic operating condition. Results also indicate a decrease in the annually minimum value of the storage tank temperature with a decrease in the energy storage tank size and/or solar collector area. © 2012 Elsevier Ltd.

Yumrutas R.,University of Gaziantep | Unsal M.,Halic University
Energy Education Science and Technology Part A: Energy Science and Research | Year: 2012

This study deals with modeling and performance analysis of a house heating system with ground coupled heat pump. The heating system consists of an underground thermal energy storage (TES) tank, a heat pump and a house. An analytical model is presented for finding the thermal performance of the heating system. The model developed is based on formulations for the transient heat transfer problem outside the TES tank, for the energy needs of the heat pump and for the house. The solution of the problem formulation is obtained using a similarity transformation technique. Expressions for energy consumption of the heat pump and house are derived as a function of inside design air, ambient air and TES temperatures. An interactive computer program based on the analytical model is prepared for finding hourly variation of water temperature in the TES tank, coefficient of performance (COP) of heat pump and timespan required to attain an annually periodic operating condition. Results indicate that 5 to 7 years will be a sufficient timespan required for the system to attain an annually periodic operating condition. © Sila Science.

Karan O.,Halic University | Bayraktar C.,Halic University | Gumuskaya H.,Gediz University | Karlik B.,University of Konya
Expert Systems with Applications | Year: 2012

Pervasive computing is often mentioned in the context of improving healthcare. This paper presents a novel approach for diagnosing diabetes using neural networks and pervasive healthcare computing technologies. The recent developments in small mobile devices and wireless communications provide a strong motivation to develop new software techniques and mobile services for pervasive healthcare computing. A distributed end-to-end pervasive healthcare system utilizing neural network computations for diagnosing illnesses was developed. This work presents the initial results for a simple client (patient's PDA) and server (powerful desktop PC) two-tier pervasive healthcare architecture. The computations of neural network operations on both client and server sides and wireless network communications between them are optimized for real time use of pervasive healthcare services. © 2011 Elsevier Ltd. All rights reserved.

Onder O.,Halic University | Gumuskaya H.,Gediz University
Procedia Computer Science | Year: 2011

Social network sites (SNSs) are becoming the platforms where socialization is practiced widely. The users of SNSs like Facebook and Twitter are increasing rapidly. Parallel to the increasing developments of social networking in the world, SNSs have started to appear and grow in different fields. The improvements of SNSs and widening of their fields of use have brought up the term "social media". Social media is the dialogue and interaction of users with each other using Internet. Social media is formed by the collection of contents that are produced by users in a frame; social media is also the platform that the content is published. Social media uses social networks like Facebook, Myspace, Google Groups, Twitter and Friendfeed as tools. In this paper, a SNS, Architectural Platform (AP), for architects is presented. AP that consists of architectural catalogues, news, announcements, and sharing design ideas and user profiles in its content is developed. The design purpose of AP is to create a meeting point for the producers, architects, interior architects, academicians, students and other visitors who are interested in architecture. AP which is the first national SNS in its area in Turkey presents novel design and implementation ideas for a SNS targeted for architects. AP SNS which is active since February 2010 has reached 43.000 unique visitors as of June 2010. © 2010 Published by Elsevier Ltd.

The aim of this study was to correlate the results of experimental data using DTA method and predictions of artificial neural network (ANN) and multivariate linear regression (MLR). Thermal decomposition of polymers was analyzed by simultaneous DTA method, and kinetic parameters (critical points, the change of enthalpy and entropy) of polymers were investigated. A computer model based on multilayer feed forwarding back propagation and multilayer linear regression model were used for the prediction of critical points, phase transitions of low-density polyethylene (LDPE) and mid-density polyethylene. As a result of our study, we concluded that ANN model is more suitable than MLR about prediction of experimental data. © 2010 Akadémiai Kiadó, Budapest, Hungary.

Berber E.,Halic University
Clinical and Applied Thrombosis/Hemostasis | Year: 2011

Factor XI (FXI) deficiency is a rare autosomal bleeding disease associated with genetic defects in the FXI gene. It is a heterogeneous disorder with variable tendency in bleeding and variable causative FXI gene mutations. It is characterized as a cross-reacting material-negative (CRM-) FXI deficiency due to decreased FXI levels or cross-reacting material-positive (CRM+) FXI deficiency due to impaired FXI function. Increasing number of mutations has been reported in FXI mutation database, and most of the mutations are affecting serine protease (SP) domain of the protein. Functional characterization for the mutations helps to better understand the molecular basis of FXI deficiency. Prevalence of the disease is higher in certain populations such as Ashkenazi Jews. The purpose of this review is to give an overview of the molecular basis of congenital FXI deficiency. © The Author(s) 2011.

Irmak-Yazicioglu M.B.,Halic University
Oncology Research and Treatment | Year: 2016

Gastric cancer is a genetically heterogeneous disease that causes cancer-related deaths worldwide. Although many studies on this disease have been performed, the molecular mechanisms of gastric tumorigenesis, invasion, and metastasis have still not been identified. MicroRNAs (miRNAs) are endogenously coded small RNA molecules, 18-25 nucleotides in length, that regulate gene expression at the post-transcriptional level. They are required for physiological activities in the cell, including development, proliferation, differentiation, and apoptosis. Research has now indicated their importance in carcinogenesis, with miRNA profiling revealing differences in the tumor and the normal tissue in several cancers. This difference in the expression pattern might lead to disrupted regulation of genes such as tumor suppressor genes and proto-oncogenes that are involved in cell cycle control, proliferative pathways, apoptosis, and metastasis in gastric carcinogenesis. Genes encoding miRNAs have been characterized as novel proto-oncogenes and tumor-suppressor genes based on findings that these miRNAs control malignant phenotypes. miRNA deregulation promotes cell-cycle progression, confers resistance to apoptosis, and enhances invasiveness and metastasis. Deregulated miRNAs affect the regulation of their target genes. Knowing the targets of miRNAs is of great importance for identifying the molecular mechanisms behind gastric carcinogenesis and forms the focus of this review. © 2016 S. Karger GmbH, Freiburg.

Yilmaz H.G.,Halic University
Turkiye Fiziksel Tip ve Rehabilitasyon Dergisi | Year: 2014

Causing rotation and bending of the spine, scoliosis leads to postural changes. Predominantly, the abdominal muscles, thorax, back, and low back extensors are affected. However, it also causes biomechanical changes of the pelvis, shoulder girdle, and even lower extremities and feet. For this reason, a thorough examination of the musculoskleletal system has to be performed for every patient. After determination of the problems, in addition to convenient therapeutic alternatives, exercise therapy and physiotherapy have to be planned individually. In the literature, there are various exercise methodologies, which are named Schroth, Dobomed, Method Lyonnaise, myofasial relase, and side shift. All of these exercise therapies share the same basic principles. They all are based on elongating the short muscles, relaxing the stretched muscles, and using diaphragmatic and deep breath techniques during the practice. Many of these applications place emphasis on specific training and certification in this field. In fact, every physiatrist has the knowledge of composing an exercise program for scoliosis. It is very important to make a good evaluation of the patient and to employ a good therapeutic approach for his problematic segments, muscles, and postural disturbances. It is essential to have experience and sufficient practice in this area, to spare the maximum time needed for the patients, and to follow them up by consistent controls. © 2014 by Turkish Society of Physical Medicine and Rehabilitation.

Koksal M.,Halic University
International Journal of Circuit Theory and Applications | Year: 2013

In this article, a general all-pole current transfer function synthesis procedure using current backward transconductance amplifiers (CBTAs) is proposed. The proposed configuration uses n current backward transconductance amplifiers and n grounded capacitors as the only type of passive elements. The circuit is eligible to realize any all-pole transfer characteristics with a given strictly Hurwitz (stable) denominator polynomial. Further, it is straightforward to find the values of the passive elements from the coefficients of this polynomial by using the Routh-Hurwitz algorithm as in the realization of a two-element kind passive network synthesis. In this sense and as far as the author's knowledge, it is the only active structure that can be synthesized like a passive two-element kind Cauer circuit. The simulations that are performed using PSPICE exhibit satisfactory results coherent with the theory. © 2011 John Wiley & Sons, Ltd.

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