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PubMed | Hamilton Health Sciences, Nancy University Hospital Center, King Saud University, d Exercise Works Ltd and 7 more.
Type: Journal Article | Journal: Journal of medical engineering & technology | Year: 2016

Coronary heart disease (CHD) is a major disease burden globally and in China, but secondary prevention among CHD patients remains insufficient. Mobile health (mHealth) technology holds promise for improving secondary prevention but few previous studies included both provider-facing and patient-directed measures. We conducted a physician needs assessment survey (n=59), physician interviews (n=6), one focus group and a short cellphone message validation survey (n=14) in Shanghai and Hainan, China. Based on these results, we developed a multifaceted mHealth intervention that includes: (1) a provider-facing bilingual mobile app guiding prescription of evidence-based medications for secondary prevention and (2) a patient-directed short messaging system automatically sending reminders to patients regarding medication adherence and lifestyle changes (4-5 messages per week for 12 weeks). This combined intervention has the potential to improve secondary prevention of CHD and to be adapted to other countries and healthcare conditions.


Hua R.,Hainan Nongken General Hospital
World Chinese Journal of Digestology | Year: 2015

AIM: To evaluate the effects of programed emergency care in patients with severe acute pancreatitis. METHODS: Fifty-eight patients with severe acute pancreatitis treated from January 2013 to December 2013 at our hospital were included in an observat ion group to implement programed emergency care, and 55 patients with severe acute pancreatitis treated from January 2012 to December 2012 at our hospital were included in a control group to receive routine emergency care. The length of hospital stay after intervention, satisfaction to nursing care, Karnofsky performance status (KPS) and Spitzer quality of life score were compared for the two groups. RESULTS: In the observation group, 39 (67.2%) cases were very satisfied, 18 (31.0%) satisfied, and 1 (1.7%) not satisfied with the nursing care. The corresponding figures in the control group were 23 (41.8%), 25 (45.5%), and 7 (12.7%), respectively. There were significant differences between the two groups (P < 0.05). The length of hospital stay was significantly shorter in the observation group than in the control group (15.4 d ± 2.2 d vs 21.4 d ± 4.6 d, P < 0.01). KPS score was significantly higher in the observation group (76.9 ± 14.3 vs 61.4 ± 10.2, P < 0.01), and the scores of all dimensions of the quality of life scale were significantly higher in the observation group (P < 0.01). CONCLUSION: Implementation of programed emergency nursing care in patients with severe acute pancreatitis can significantly reduce hospital stay and improve patient’s satisfaction to nursing work, patient’s health status, and quality of life. © 2015 Baishideng Publishing Group Inc. All rights reserved.


Liu J.L.,Hainan Nongken General Hospital | Zhang S.Q.,Anhui Medical University | Zhang S.Q.,State Key Laboratory Incubation Base of Dermatology | Zeng H.M.,Affiliated Hospital
Journal of the European Academy of Dermatology and Venereology | Year: 2013

Objectives To determine whether ApaI, BsmI, FokI or TaqI polymorphisms in vitamin D receptor (VDR) gene confer susceptibility to psoriasis. Methods All related association studies published before January 2012 were retrieved and eligible ones were included in our meta-analysis. For each of the four polymorphisms, we explored the significance of the associations for the allele contrast as well as the recessive and dominant models in overall samples, Caucasians and East Asians. Heterogeneity was identified by sensitivity analysis and publication bias was examined by funnel plot and Egger's test. Results 12 studies that met our selection criteria were included. For ApaI polymorphism, the dominant model for allele a in Caucasians produced a significant result [heterogeneity χ2=3.46, P = 0.177, I2=42.2%; OR fixed-effect model = 1.398 (1.011-1.934), z = 2.03, P = 0.043]. While in East Asians, pooling analysis under any genetic model acquired no-significant result. Significant heterogeneity was identified among East Asian studies and a Korean study accounted mostly for the heterogeneity detected. The heterogeneities were no longer statistically significant after removing this study, and the results of re-analyses in remaining studies have not been affected. Regarding TaqI polymorphism, the allele contrast discovered significant association between allele T and psoriasis susceptibility in Caucasians [heterogeneity χ2 = 4.35, P = 0.226, I2 = 31.1%; ORfixed-effect model = 1.287 (1.067-1.551), z = 2.64, P = 0.008]. As for the BsmI and FokI polymorphisms, allele contrast, recessive and dominant models produced non-significant results in either Caucasians or East Asians. The funnel plots and Egger's tests found no publication bias presenting in the studies analyzed. Conclusions This meta-analysis showed that ApaI, TaqI polymorphisms in VDR gene correlate with psoriasis in Caucasians. © 2012 The Authors. Journal of the European Academy of Dermatology and Venereology © 2012 European Academy of Dermatology and Venereology.


PubMed | Hainan Nongken General Hospital
Type: Journal Article | Journal: Journal of the European Academy of Dermatology and Venereology : JEADV | Year: 2013

To determine whether ApaI, BsmI, FokI or TaqI polymorphisms in vitamin D receptor (VDR) gene confer susceptibility to psoriasis. Methods All related association studies published before January 2012 were retrieved and eligible ones were included in our meta-analysis. For each of the four polymorphisms, we explored the significance of the associations for the allele contrast as well as the recessive and dominant models in overall samples, Caucasians and East Asians. Heterogeneity was identified by sensitivity analysis and publication bias was examined by funnel plot and Eggers test.12 studies that met our selection criteria were included. For ApaI polymorphism, the dominant model for allele a in Caucasians produced a significant result [heterogeneity (2) = 3.46, P = 0.177, I(2) = 42.2%; OR(fixed-effect model) = 1.398 (1.011-1.934), z = 2.03, P = 0.043]. While in East Asians, pooling analysis under any genetic model acquired no-significant result. Significant heterogeneity was identified among East Asian studies and a Korean study accounted mostly for the heterogeneity detected. The heterogeneities were no longer statistically significant after removing this study, and the results of re-analyses in remaining studies have not been affected. Regarding TaqI polymorphism, the allele contrast discovered significant association between allele T and psoriasis susceptibility in Caucasians [heterogeneity (2) = 4.35, P = 0.226, I(2) = 31.1%; OR(fixed-effect model) = 1.287 (1.067-1.551), z = 2.64, P = 0.008]. As for the BsmI and FokI polymorphisms, allele contrast, recessive and dominant models produced non-significant results in either Caucasians or East Asians. The funnel plots and Eggers tests found no publication bias presenting in the studies analyzed.This meta-analysis showed that ApaI, TaqI polymorphisms in VDR gene correlate with psoriasis in Caucasians.

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