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Chang D.-D.,Chinese Academy of Sciences | Chang D.-D.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | Zuo W.-J.,Chinese Academy of Sciences | Zuo W.-J.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | And 4 more authors.
Journal of Asian Natural Products Research | Year: 2012

A new drimane sesquiterpene, 1,7-dihydroxyconfertifolin (1), along with two known compounds 2 and 3, was isolated from endophytic fungus A12 of Dracaena cambodiana. The new compound was elucidated by HR-ESI-MS and spectroscopic techniques (IR, UV, 1D, and 2D NMR). Compound 2 showed inhibitory bacterial activity against Staphylococcus aureus with diameter of the inhibition zone of 13.5mm. © 2012 Copyright Taylor and Francis Group, LLC. Source


Dai H.-f.,Chinese Academy of Sciences | Dai H.-f.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | Wang H.,Chinese Academy of Sciences | Wang H.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | And 6 more authors.
Chemistry of Natural Compounds | Year: 2012

Phytochemical studies on the stem of Dracaena cambodiana led to the discovery of two new biflavonoids, 8-methylsocotrin-3′-methoxy-4′-ol (1) and 8-methylsocotrin-4′-methoxy-3′-ol (2), together with a known biflavonoid, 8-methylsocotrin-4′-ol (3). Their structures were identified by means of HR-ESI-MS and detailed spectral analysis (UV, IR, and 1D and 2D NMR). © 2012 Springer Science+Business Media, Inc. Source


Mei W.-L.,Chinese Academy of Sciences | Mei W.-L.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | Lin F.,Chinese Academy of Sciences | Lin F.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | And 6 more authors.
Chinese Journal of Natural Medicines | Year: 2012

Aim: To investigate the chemical constituents in the fruits of Aquilaria sinensis. Methods: The chemical constituents were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were elucidated on the basis of spectroscopic analysis. Results: Five compounds were isolated and identified as hexanorcucurbitacin I (1), cucurbitacin I (2), cucurbitacin D (3), isocucurbitacin D (4), and neocucurbitacin B (5). Conclusion: Compounds 1-5 were reported from Aquilaria genus for the first time. Compounds 1, 2, 4, and 5 showed cytotoxic activities against K562, SGC-7901 and SMMC-7721. © 2012 China Pharmaceutical University. Source


Luo Y.,Chinese Academy of Sciences | Wang H.,Chinese Academy of Sciences | Wang H.,Haikou Key Laboratory for Research and Development of Tropical Natural Products | Zhao Y.-X.,Chinese Academy of Sciences | And 8 more authors.
Planta Medica | Year: 2011

Chemical studies on the constituents from the dragon's blood of Dracaena cambodiana led to the discovery of three new flavonoid derivatives (13) and six known compounds (49). The structures of the three new compounds were elucidated by NMR and MS spectroscopic analyses. All compounds were evaluated for their growth inhibitory activity against human cell lines K-562, SMMC-7721, and SGC-7901, as well as antibacterial activities against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). As a result, compounds 1, 2, 5, 7, and 9 showed cytotoxicity against K-562, SMMC-7721, and SGC-7901 cell lines. All these compounds were observed to exhibit antibacterial activities against S. aureus, and compounds 14, 6, 8, and 9 were observed to exhibit antibacterial activity against MRSA. © 2011 Georg Thieme Verlag KG Stuttgart . New York . Source


Li S.-S.,Chinese Academy of Sciences | Li S.-S.,Hainan University | Hu L.-F.,Chinese Academy of Sciences | Zhao Y.-X.,Chinese Academy of Sciences | And 11 more authors.
Journal of Asian Natural Products Research | Year: 2011

A new diterpene, named yucalexin P-23 (1), together with three known compounds, yucalexin P-15 (2), protocatechuic acid (3), and catalpinic acid (4), was isolated from the stems of Manihot esculenta. Their structures were determined by means of physicochemical evidence and spectral analysis. Compounds 3 and 4 exhibited antimicrobial activity. © 2011 Taylor & Francis. Source

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