The University of Haifa is a public research university in Haifa, Israel.The University of Haifa was founded in 1963 by Haifa mayor Abba Hushi, to operate under the academic auspices of the Hebrew University of Jerusalem, Haifa university is located on Mount Carmel. In 1972 University of Haifa declared its independence and became the sixth academic institution in Israel and the fourth university.About 18,100 undergraduate and graduate students study in the university a wide variety of topics, specializing in social science, humanities, law and education. The University is broadly divided into six Faculties: Humanities, Social science, Law, Science and Science Education, Social Welfare and Health Studies, and Education. There is also the Graduate School of Management, The Leon H. Charney School of Marine science and the Continuing Education and Extension Studies.Beyond the objective of a first-rate higher education, the University of Haifa aims to provide equal educational opportunities to all sectors of the society, and in particular to encourage mutual understanding and cooperation between the Jewish and Arab populations on and off campus.The university is a home for students from all the edges of the Israeli society - Jews, Muslims, Christians, Druze, religious and secular students and also many students from all over the world who study in the international school.The University of Haifa is home to the Hecht Museum of archeology and art, several research centers and institutes, including the Evolution Institute, Center for the Study of the Information Society, Center for the Study of National Security, Tourism Research Center, and more. The University also hosts a large IBM research center on its campus. Wikipedia.
Haifa University | Date: 2016-12-08
The present invention provides an antagonist of a Bcl-2 prosurvival protein containing a BH3-like domain. The antagonist of the invention comprises ARTS and any fragment or peptide that comprises a BH3-like domain. The invention further provides compositions, combined compositions and kits as well as methods for treating Bcl-2 over-expressing disorders.
Haifa University | Date: 2015-03-18
An active agent capable of reducing quinone reductase 2 activity, for use in improvement of cognition in a subject is provided. Such an active agent may be a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 or an inhibitor of quinone reductase 2 activity. A vector comprising a nucleic acid molecule that reduces the gene expression level of quinone reductase 2 and a pharmaceutical composition comprising an active agent capable of reducing quinone reductase 2 activity or said vector are provided as well.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: ICT-32-2014 | Award Amount: 3.96M | Year: 2015
Online banking, e-commerce, telemedicine, mobile communication, and cloud computing depend fundamentally on the security of the underlying cryptographic algorithms. Public-key algorithms are particularly crucial since they provide digital signatures and establish secure communication without requiring in-person meetings. Essentially all applications today are based on RSA or on the discrete-logarithm problem in finite fields or on elliptic curves. Cryptographers optimize parameter choices and implementation details for these systems and build protocols on top of these systems; cryptanalysts fine-tune attacks and establish exact security levels for these systems. Alternative systems are far less visible in research and unheard of in practice. It might seem that having three systems offers enough variation, but these systems are all broken as soon as large quantum computers are built. The EU and governments around the world are investing heavily in building quantum computers; society needs to be prepared for the consequences, including cryptanalytic attacks accelerated by these computers. Long-term confidential documents such as patient health-care records and state secrets have to guarantee security for many years, but information encrypted today using RSA or elliptic curves and stored until quantum computers are available will then be as easy to decipher as Enigma-encrypted messages are today. PQCRYPTO will allow users to switch to post-quantum cryptography: cryptographic systems that are not merely secure for today but that will also remain secure long-term against attacks by quantum computers. PQCRYPTO will design a portfolio of high-security post-quantum public-key systems, and will improve the speed of these systems, adapting to the different performance challenges of mobile devices, the cloud, and the Internet of Things. PQCRYPTO will provide efficient implementations of high-security post-quantum cryptography for a broad spectrum of real-world applications.
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2016 | Award Amount: 870.02K | Year: 2016
Following previous TEN years of successful implementation of European Researchers Night in Israel we will have: o Venues covering the whole country. o Involvement of the academic community including Israel Ministry of Science, Technology and Space (MOST), all major research universities, leading collages and three science museums. o Awareness campaign at national level managed and funded by the Israel Ministry of Science, Technology and Space. o Groups of junior-high and high-school students (ages 12-18) will be invited by each partner to take part in each venue. We are ready and proud to implement European Researchers Night 2016 & 2017. All of the partners involved in the project have the experience of running successful European Researchers Nights events. With the successive increase in number of visitors along the years and the reputation of the event we are expecting more than 55,000 visitors each year. Same management as in 2011, 2012, 2013, 2014, 2015 successful events. Proposal covers both 2016 & 2017 European Researchers Night events.
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: INFRADEV-03-2016-2017 | Award Amount: 2.72M | Year: 2017
Europe has a long and rich tradition as a centre for the arts and humanities. However, the digital transformation poses challenges to the arts and humanities research landscape all over the world. Responding to these challenges the Digital Research Infrastructure for Arts and Humanities (DARIAH) was launched as a pan-European network and research infrastructure. After expansion and consolidation, which involved DARIAHs inscription on the ESFRI roadmap, DARIAH became a European Research Infrastructure Consortium (ERIC) in August 2014. The DESIR project sets out to strengthen the sustainability of DARIAH and firmly establish it as a long-term leader and partner within arts and humanities communities. By DESIRs definition, sustainability is an evolving 6-dimensional process, divided into the following challenges: Dissemination: DESIR will organise a series dissemination events, including workshops in the US and Australia, to promote DARIAH tools and services and initiative collaborations. Growth: DESIR sets out to prepare the ground for establishing DARIAH membership in six new countries: the UK, Finland, Spain, Switzerland, Czech Republic and Israel. Technology: DESIR will widen the DARIAH research infrastructure in three areas, vital for DARIAHs long-term sustainability: entity-based search, scholarly content management, visualization and text analytic services. Robustness: DESIR will make DARIAHs organizational structure and governance fit for the future and develop a detailed business plan and marketing strategy. Trust: DESIR will measure the acceptance of DARIAH, especially in new communities, and define mechanisms to support trust and confidence in DARIAH. Education: Through training and teaching DESIR will promote the use of DARIAH tools and services. The DESIR consortium is composed of core DARIAH members, representatives from potential new DARIAH members and external technical experts. It is balanced between the different European regions.
Tomer R.,Haifa University
Cerebral cortex (New York, N.Y. : 1991) | Year: 2013
Pseudoneglect is traditionally viewed as reflecting right hemisphere specialization for processing spatial information, resulting in orienting toward the contralateral, left, hemispace. Recent evidence suggests that healthy individuals differ from each other in both direction and magnitude of orienting bias, and moreover, the bias displayed by a person is consistent across time, suggesting that it may represent a trait of the individual. Animal studies reveal consistent orienting bias within an individual, which reflects asymmetry in dopaminergic brain systems. We measured basal D2-like receptor binding using positron emission tomography and the high-affinity ligand [F-18]fallypride, to test the hypothesis that asymmetry in dopaminergic neurotransmission in healthy humans modulates the orienting bias in humans. As predicted, we found that individual differences in the direction and magnitude of the orienting bias were strongly associated with the pattern of asymmetric binding of dopamine (DA) D2 receptors in the striatum, as well as clusters in the frontal and temporal cortex. These findings show for the first time that orienting bias reflects individual differences in the lateralization of DA systems in the healthy human brain.
Maroun M.,Haifa University
Neuroscientist | Year: 2013
Anxiety disorders are among the most common mental health problems; deficits in extinction have been implicated as a possible risk factor for the development of these disorders. Fear extinction refers to the ability to adapt as situations change by learning to suppress a previously acquired fear. Attention is directed toward the medial prefrontal cortex (mPFC) and the interaction it has with the amygdala as this circuit has crucial roles in both the acquisition and the extinction of fear associations. Here, we review converging evidence from different laboratories pointing to multiple roles that the mPFC has in fear regulation. Research on rodents indicates opposing roles that the different subregions of the mPFC have in exciting and inhibiting fear. In addition, this review aims to survey the findings addressing the mechanisms by which the mPFC regulates fear. Data from our laboratory and others show that changes in plasticity in the mPFC could be one of the mechanisms mediating extinction of fear. Recent findings on rodents and nonhuman primates report that modifying plasticity in the mPFC alters fear and affects extinction, suggesting that targeting plasticity in the mPFC could constitute a therapeutic tool for the treatment of anxiety disorders. © The Author(s) 2012.
Lamprecht R.,Haifa University
Progress in Neurobiology | Year: 2014
The ability to efficiently store memories in the brain is a fundamental process and its impairment is associated with multiple human mental disorders. Evidence indicates that long-term memory (LTM) formation involves alterations of synaptic efficacy produced by modifications in neural transmission and morphology. The actin cytoskeleton has been shown to be involved in these key neuronal processes by subserving events such as presynaptic vesicle movement, postsynaptic glutamate receptors trafficking and dendritic spines morphogenesis. Actin cytoskeleton dynamics and structure underlying such cellular events can be regulated by extracellular signals through its regulatory proteins. Recent findings show that the actin cytoskeleton and its regulatory proteins are needed for memory formation and extinction in different organisms throughout the phyla from invertebrates such as Caenorhabditis elegans and Drosophila to mammalians. The actin cytoskeleton and its regulatory proteins participate in the formation of various types of memories that are subserved by different neurons and brain regions. The actin cytoskeleton may therefore mediate between synaptic transmission during learning and long-term cellular alterations mandatory for memory formation. © 2014 Elsevier Ltd.
Shamay-Tsoory S.G.,Haifa University
Neuroscientist | Year: 2011
Human empathy relies on the ability to share emotions as well as the ability to understand the other's thoughts, desires, and feelings. Recent evidence points to 2 separate systems for empathy: an emotional system that supports our ability to empathize emotionally and a cognitive system that involves cognitive understanding of the other's perspective. Converging evidence from neuroimaging and lesion studies shows that a neural network that includes the inferior frontal gyrus and the inferior parietal lobule is necessary for emotion recognition and emotional contagion. On the other hand, the involvement of the ventromedial prefrontal cortex, temporoparietal junction, and the medial temporal lobe in self-reflection and autobiographical memory places these key regions as necessary for cognitive empathy. The proposed dissociation between these systems is supported by recent neurochemical experiments involving administration of oxytocin as well as by ethological, psychiatric, and developmental studies. Finally, although the emotional and cognitive systems appear to work independently, every empathic response may still evoke both components to some extent, depending on the social context. © The Author(s) 2011.
Agency: Cordis | Branch: H2020 | Program: ERC-STG | Phase: ERC-StG-2015 | Award Amount: 1.50M | Year: 2016
Social-science explanations for rising wage inequality have reached a dead end. Most economists argue that computerization has been primarily responsible, while on the other side of the argument are sociologists and political scientists who stress the role of political forces in the evolution process of wages. I would like to use my knowledge and experience to come up with an original theory on the complex dynamics between technology and politics in order to solve two unsettled questions regarding the role of computerization in rising wage inequality: First, how can computerization, which diffused simultaneously in rich countries, explain the divergent inequality trends in Europe and the United States? Second, what are the mechanisms behind the well-known observed positive correlation between computers and earnings? To answer the first question, I develop a new institutional agenda stating that politics, broadly defined, mitigates the effects of technological change on wages by stimulating norms of fair pay and equity. To answer the second question, I propose a truly novel perspective that conceptualizes the earnings advantage that derives from computerization around access to and control of information on the production process. Capitalizing on this new perspective, I develop a new approach to measuring computerization to capture the form of workers interaction with computers at work, and build a research strategy for analysing the effect of computerization on wages across countries and workplaces, and over time. This research project challenges the common understanding of technologys role in producing economic inequality, and would thereby significantly impact all of the abovementioned disciplines, which are debating over the upswing in wage inequality, as well as public policy, which discusses what should be done to confront the resurgence of income inequality.