Thi Tran Nguyen Binh, Vietnam
Thi Tran Nguyen Binh, Vietnam

Hai Phong Medical University is a public university established in September 1979 in Hai Phong, Vietnam.In 2006, the Minister of Health approved the development strategy of Hai Phong Medical University to be the University of Medicine and Pharmacy in Hai Phong, adding new faculties: the faculty of pharmacy, the faculty of odonto-stomatology, the faculty of public health and the faculty of nursing. Wikipedia.

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PubMed | University of Tübingen, Hai Phong Medical University and 108 Military Central Hospital
Type: | Journal: BMC infectious diseases | Year: 2016

Blood cultures are commonly employed to identify bacterial pathogens causing sepsis. PCR assays to diagnose septicemia require extraction of bacterial DNA from blood samples and thus, delay the initiation of appropriate antimicrobial treatment. The presence of abundant human DNA may hamper the sensitivity of PCR in the detection of bacteria.We used serial dilutions of E. Coli spiked pseudo-blood-sepsis samples to develop a simple method that combines the use of a polar detergent solvent and adjustment of the basic pH to remove human DNA. A 16S rRNA gene-based screening algorithm was established to differentiate Gram-positive and Gram-negative groups of bacteria and the family of Enterobacteriaceae. A stringent validation with appropriate controls was implemented. The method of human DNA removal was then applied on 194 sepsis blood samples and 44 cerebrospinal fluid (CSF) samples by real-time PCR.This uncomplicated and straightforward approach allows to remove up to 98% of human DNA from peripheral blood of septic patients. The inhibitory effect of human DNA is efficiently prevented and the detection limit of real-time PCR is increased to 10 E. Coli CFUs/ml. This sensitivity is 10 times higher compared to conventional real-time PCR assays. The classical blood culture detected 58/194 (30%) of sepsis and 9/44 (21%) of CSF samples. Out of the 194 blood samples tested, the conventional real-time PCR targeting 13 common sepsis causing pathogens correctly detected the bacterial DNA in 16/194 (8%) only and 14/44 (32%) in cerebrospinal fluid samples. Our newly established approach was able to provide correct diagnoses in 78 (40%) of the 194 blood samples and in 14 (32%) of the CSF samples. The combination of both blood cultures and our technique raised the rate of sepsis diagnoses to 112/194 (58%). Of the total group tested positive, 46 (24%) cases showed overlap with the classical methodology.We report a simple optimized in-house protocol for removal of human DNA from blood sepsis samples as a pre-analytical tool to prepare DNA for subsequent PCR assays. With the detection increase of our in-house DNA removal approach, subsequent PCR assays can reach detection limits of 10 E. coli CFUs/ml and significantly improve the diagnostic rate in blood sepsis cases.

Trung N.T.,Quy Nhon University | Thu Trang N.T.,Hai Phong Medical University | Ngan V.T.,Quy Nhon University | Quang D.T.,Hue University | Nguyen M.T.,Catholic University of Leuven
RSC Advances | Year: 2016

Interactions of ethylene and its 1,2-dihalogenated derivatives with CO2 induce the formation of twenty four molecular complexes with stabilization energies in the range of 1.1 to 7.5 kJ mol-1 as computed at the CCSD(T)/aug-cc-pVTZ//MP2/aug-cc-pVDZ level. The stability of the parent C2H4⋯CO2 complex is due to a π⋯π∗ interaction which has not yet been reported in the complexes of CO2-philic compounds and CO2. The cis-XCH=CHX⋯CO2 complexes are found to be slightly more stable than the trans-XCH=CHX⋯CO2, with X = F, Cl and Br. Generally, the overall stabilization energy of each complex is determined by the C-H⋯O hydrogen bond and the C-X⋯C Lewis acid-base interaction, in which the latter plays a larger role. Substitution of two H atoms in CH2=CH2 by the same halogen atoms stabilizes the complexes XCH=CHX⋯CO2, and for the same dihalogenated derivatives, the stability of XCH=CHX⋯CO2 tends to increase from X = F via Cl and to Br. The obtained results suggest that the contraction of the C-H bond involved in the C-H⋯O hydrogen bond and the blue-shift of its stretching frequency depend not only on a polarization of the C-H bond in the isolated monomer but also on the geometric shape of the complex formed. © The Royal Society of Chemistry 2016.

Le D.-N.,Hai Phong Medical University | Van V.N.,Duy Tan University | Giang T.T.T.,Vietnam National University, Hanoi
Advances in Intelligent Systems and Computing | Year: 2016

Nowadays, the Distributed Denial of Service (DDoS) attack is still one of the most common and devastating security threats to the internet. This problem is progressing quickly, and it is becoming more and more difficult to grasp a global view of the problem. In this paper, we propose a new defense method used the bandwidth in second that a server can use for UDP packets is set as a parameter for controlling a DDoS attack by using the number of UDP packets available. It is registered in the private security policy as a parameter for detecting a flood attack. The efficiency of our proposed method was also proved in the experiments with NS2. DDoS attack is controlled effectively by the private security policy the bandwidth of the regular traffic would be maintained. © Springer India 2016.

Long H.V.,University of Transport and Communications | Son N.T.K.,Hanoi University | Ha N.T.M.,Hai Phong Medical University | Son L.H.,Vietnam National University, Hanoi
Fuzzy Optimization and Decision Making | Year: 2014

Fuzzy hyperbolic partial differential equation, one kind of uncertain differential equations, is a very important field of study not only in theory but also in application. This paper provides a theoretical foundation of numerical solution methods for fuzzy hyperbolic equations by considering sufficient conditions to ensure the existence and uniqueness of fuzzy solution. New weighted metrics are introduced to investigate the solvability for boundary valued problems of fuzzy hyperbolic equations and an extended result for more general classes of hyperbolic equations is initiated. Moreover, the continuity of the Zadeh’s extension principle is used in some illustrative examples with some numerical simulations for $$\alpha $$α-cuts of fuzzy solutions. © 2014, Springer Science+Business Media New York.

Tran V.T.,Kanazawa University | Tran V.T.,Hai Phong Medical University | Ishizaki A.,Kanazawa University | Nguyen C.H.,Kanazawa University | And 6 more authors.
AIDS Research and Human Retroviruses | Year: 2012

We reported previously that the prevalence of drug-resistant HIV-1 among antiretroviral therapy (ART)-naive individuals in Northern Vietnam was 2.9% in 2007 and 6.2% in 2008. To investigate the continuing trend of prevalence, we collected plasma samples from 958 individuals in Hai Phong and Hanoi in 2009, extracted viral RNA from HIV-1 antibody-positive samples, and analyzed them genetically. HIV-1 antibody prevalence was 26.8% in injecting drug users (n=302), 13.4% in female sex workers (n=284), 0.5% in blood donors (n=206), and 0.6% in pregnant women (n=166). All HIV-1 strains were CRF01-AE. Nonnucleoside reverse-transcriptase inhibitor resistance mutations were found in two (2.0%) of the 102 successfully analyzed cases (one case with the Y181C and one with the K101E). No nucleoside reverse-transcriptase inhibitor resistance or protease inhibitor resistance mutations were detected. The prevalence of circulating ART-resistant HIV-1 in Northern Vietnam did not increase from 2007 to 2009, although the rate of ART coverage did increase. © 2012, Mary Ann Liebert, Inc.

Dai H.Q.,Quy Nhon University | Tri N.N.,Quy Nhon University | Thu Trang N.T.,Hai Phong Medical University | Trung N.T.,Quy Nhon University
RSC Advances | Year: 2014

The interactions of the host molecules CH3COCHR2 (R = CH3, H, F, Cl, Br) with the guest molecules CO2 and FCN (X = F, Cl, Br) induce significantly stable complexes with stabilization energies, obtained at the CCSD(T)/6-311++G(3df,2pd)//MP2/6-311++G(2d,2p) level, in the range of 9.2-14.5 kJ mol-1 by considering both ZPE and BSSE corrections. The CH3COCHR2⋯XCN complexes are found to be more stable than the corresponding CH3COCHR2⋯ CO2 ones. The overall stabilization energy has contributions from both the >CO⋯C Lewis acid-base and C-H⋯O(N) hydrogen bonded interactions, in which the crucial role of the former is suggested. Remarkably, we propose a general rule to understand the origin of the C-H⋯O(N) hydrogen bonds on the basis of the polarization of a C-H bond of a proton donor and the gas phase basicity of a proton acceptor. In addition, the present work suggests that the >CO group can be a valuable candidate in the design of CO2-philic and adsorbent materials, and in the extraction of cyanide derivatives from the environment. © 2014 The Royal Society of Chemistry.

Bao L.N.,Duy Tan University | Le D.-N.,Hai Phong Medical University | van Chung L.,Duy Tan University | Nguyen G.N.,Duy Tan University
Advances in Intelligent Systems and Computing | Year: 2016

In this research, we propose the online video contextual advertisement user-oriented system. Our system is a combination of video-based face recognition using machine learning models from the camera with multimedia communications and networking streaming architecture using Meta-data structure to video data storage. The real images captured by the camera will be analyzed based on predefined set of conditions to determine the appropriate object classes. Based on the defined object class, the system will access the multimedia advertising contents database and automatically select and play the appropriate contents. We analyse existing face recognition in videos and age estimation from face images approaches. Our experiment was analyzed and evaluated in performance when we integrate analyze age from the face identification in order to select the optimal approach for our system. © Springer India 2016.

Phuong V.T.,Quy Nhon University | Trang N.T.T.,Hai Phong Medical University | Vo V.,Quy Nhon University | Trung N.T.,Quy Nhon University
Chemical Physics Letters | Year: 2014

Interactions of CO2 with CH3SZCHX2 (ZO, S; XH, CH3, F, Cl, Br) induce significantly stable complexes with interaction energies from -13.7 to -16.4 kJ mol-1 (MP2/aug-cc-pVTZ//MP2/6-311++G(2d,2p)). Remarkably, some stable shapes of CH3SZCH3CO2 are revealed for the first time. Substitution of two H atoms in a CH3 of CH3SZCH 3 by two X alike groups makes CH3SZCHX2CO 2 more stable than CH3SZCH3CO2, and their stability increases in the order F < Cl < Br < CH3. The >SO is stronger than the >SS in interacting with CO2, and they both can be valuable candidates in the design of CO2-philic materials and in the findings of materials to adsorb CO2. © 2014 Elsevier B.V. All rights reserved.

Cao T.-D.,Hanoi University of Science and Technology | Nguyen T.-N.,Hai Phong Medical University
ACM International Conference Proceeding Series | Year: 2014

The rapid development of mobile computing, social network and smart phones have led to a surge in photograph data. Efficient exploiting, searching and reusing this data have become a problem gaining increasing concerns. However, current systems are still encountering many challenges from the differences in perceiving the meaning of a photograph between human and machines. Among many different approaches, semantic web has recently been proven to be robust enough to overcome these challenges. In this paper, we propose the semantic web approach to develop a system which reduces above differences by accommodating an additional layer that annotates metadata with the original photo to describe important and useful information for the user in both content and context semi automatically. We use a mobile application that connects with a semantic web application. With above solution, the interaction of user of the photograph system becomes simple, friendly and quickly more than ever. Copyright 2014 ACM.

Le D.-N.,Hai Phong Medical University
Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering, LNICST | Year: 2015

In this paper, we proposed a novel Min-Max Ant System algorithm for dynamic resource allocation with many of service classes while maximizing the provider’s utility in service-oriented networks. The model considers a pricing scheme for the offered services and the quality of service (QoS) requirements of each service class, which operates under a probabilistic delay bound constraint. The goal is to investigate how the utility function and the resource allocation respond to changes of various parameters given the QoS requirements of each service class. Our algorithm performance is evaluated through numerical studies and our solution is approximated the optimal solution. The computational results showed that this approach is currently among the best performing algorithms and much better than previous studies for this problem. © 2015, Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, All rights Reserved.

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