Haffkine Institute of Training

Parel, India

Haffkine Institute of Training

Parel, India
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Ahluwalia S.,Haffkine Institute of Training | Shah N.,Haffkine Institute of Training
International Journal of Pharmacy and Pharmaceutical Sciences | Year: 2014

Breast cancer is one of the most common malignancies found in women and is associated with increased mortality in advanced disease. With the use of improved screening techniques and improvisation in treatment, 89% of the women diagnosed with breast cancer will survive 5 years from diagnosis. Despite significant advancement in the diagnosis and treatment of breast cancer, many patients succumb to this disease. The elucidation of aberrant signaling pathways that lead to breast cancer should help develop more effective therapeutic strategies. This review focuses on the different targets of breast cancer and how they can be acted upon by different animal venoms. © 2014, International Journal of Pharmacy and Pharmaceutical Sciences. All rights reserved.


Jadhav Y.P.,Haffkine Institute of Training | Dawane K.H.,Haffkine Institute of Training | Athlekar S.V.,Haffkine Institute of Training | Patil L.S.,Haffkine Institute of Training | And 2 more authors.
Indian Journal of Heterocyclic Chemistry | Year: 2010

Several 2-substituted anilino-4-(6-chloro-1H-cinnoline-4-one) thiazoles HBr (3a-I) were synthezied. 3-Acetyl-6-chloro-1H-cinnoline-4-one 1 was brominated using phenyltrimethylammonium tribromide (PTT) as selective a-brominating agent to obtain corresponding bromoacetyl product 2 which when condensed with various substituted phenyl thioureas yielded corresponding title compounds (3a-I). They were screened for antibacterial and antifungal activity.

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