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Chinju, South Korea

Gyeongsang National University is a national university governed under the ministry of education of Republic of Korea government and located in Jinju, South Gyeongsang Province and represents the South Gyeongsang Province of South Korea as one of 10 Flagship Korean National Universities along with Cheju National University, Chonbuk National University, Chonnam National University, Chungnam National University, Chungbuk National University, Kangwon National University, Kyungpook National University, Pusan National University, and Seoul National University.Gyoengsang National University has twelve colleges including arts, social science, natural science, engineering, agriculture and life science, management, veterinary, education, nursing, and medicine and eight graduate schools including medicine and public health, business administration, education, aerospace, industry etc. Other institutions with the university are the university library, the university museum, student center, university newspaper and broadcasting center, publishing company, institute for education of science talented, Korean language cultural center and so on. The current statistics of Gyeongsang National University shows that it has 1,681 academic staffs including 808 full-time professors, 361 administrative staffs and 24,502 students including undergraduate and graduate students enrolled. The university has three campuses and two of these are located in Jinju, South Gyeongsang Province and the other is located in Tongyeong. The main campus is located at Gajwa in the city of Jinju, Chilam campus, Jinju has the college of medicine, and Tongyeong campus, an hour from Jinju by car, has the college of Marine Science.The motto of Gyeongsang National University is Pioneer and it states that the eyes of pioneers see far beyond the present to the future. The history of the university begun as Jinju Agricultural College founded in Jinju in 1948, in 1968, accredited as national college and in 1972, renamed as Gyeongsang National College. In 1980, it was accredited as national university by the ministry of education and renamed as Gyeongsang National University. For more than 60 years since its foundation, Gyeongsang National University has been educating talented students who have served not only for local community but also for national prosperity by leading them to be bigger asset in many places such as communities, industries, businesses and so on around the country and the world.Gyeongsang National University is well known for many achievements in applied life science along with biochemistry, agricultural science, and veterinary. One of these is that the researchers at the university discovered a way to make cloned Turkish Angora cats glow red when exposed to ultraviolet light in 2007 and many alumni in these fields are working as researchers and professionals in research institutions and universities around the world. In present, the university has made its highly competitive fields of study broad to mechanical and aerospace systems engineering and new nano-materials engineering. In addition, Gyeongsang National University has made achievements in humanities and in sociology, two fields which lay the foundation for human ethics. Beside this, Gyeongsang National University is proud to have the college of Education in where great middle school teachers are educated to take responsibility for education of Republic of Korea, the college of Veterinary Medicine in where international veterinarians are trained, and the College of Marine Science to pioneer the studies of the ocean in the twenty first century. The university keeps moving on to provide advanced international education in Republic of Korea by successfully partnering in international campuses in Incheon as well as Busan-Jinhae Free Economic Zones.The Graduate School of Medicine and Public Health at Gyeongsang National University is unique medical training and research institution in South Gyeongsang Province and plans are being made with Gyeongsang National University Hospital to open a specialized medical center in the city of Changwon as the second Gyeongsang National University hospital in 2013. Gyeongsang National University Hospital opened with 419 beds in 1987 as the university hospital of Gyeongsang National University and is located next to the college of medicine in Chilam campus and has provided health care service with quality for more than 25 years and grown to a general and multispecialty medical hospital with 950 beds operating with specialty centers such as the local cancer center opened as the first local cancer center of its kinds in the country and rheumatoid arthritis center. Wikipedia.

Clinical experiences have suggested that East Asians show the higher risk of warfarin-related intracranial hemorrhage compared with Westerners. Therefore, different target of the International Normalized Ratio (INR) in East Asians (1.6-2.6) has been proposed and adapted in clinical practice. In terms with antiplatelet therapy, recent evidence has supported the concept of "therapeutic level of platelet reactivity" to balance clinical efficacy and safety in patients undergoing percutaneous coronary intervention (PCI) or those with acute coronary syndrome (ACS). In line with the warfarin experiences, multiple clinical and pharmacodynamic data from East Asians have shown their different therapeutic level of platelet reactivity following PCI or ACS (" East Asian Paradox"). Furthermore, like most cardiovascular drugs, P2Y12 receptor blockers have marked interethnic differences in the pharmacokinetics and pharmacodynamics. The currently performed clinical trials evaluating the clinical efficacy and safety of potent P2Y12 inhibitors mostly don't include enough number of East Asians to draw reliable conclusions. Therefore, dedicated research and guideline(s) for East Asians are required before we can apply Western recommendations for potent P2Y12 inhibitors in East Asian population. It is a time to consider the paradigm shift from "one-guideline-fits-all races"to "race-tailored antiplatelet therapy" in treating ACS patients. © Springer Science+Business Media 2014. Source

Myong R.S.,Gyeongsang National University
Physics of Fluids | Year: 2014

The high Mach number shock structure singularity arising in moment equations of the Boltzmann equation was investigated. The source of the singularity is shown to be the unbalanced treatment between two high order kinematic and dissipation terms caused by the overreach of Maxwellian molecule assumption. In compressive gaseous flow, the high order stress-strain coupling term of quadratic nature will grow far faster than the strain term, resulting in an imbalance with the linear dissipation term and eventually a blow-up singularity in high thermal nonequilibrium. On the other hand, the singularity arising from unbalanced treatment does not occur in the case of velocity shear and expansion flows, since the high order effects are cancelled under the constraint of the free-molecular asymptotic behavior. As an alternative method to achieve the balanced treatment, Eu's generalized hydrodynamics, consistent with the second law of thermodynamics, was revisited. After introducing the canonical distribution function in exponential form and applying the cumulant expansion to the explicit calculation of the dissipation term, a natural platform suitable for the balanced treatment was derived. The resulting constitutive equation with the nonlinear factor was then shown to be well-posed for all regimes, effectively removing the high Mach number shock structure singularity. © 2014 AIP Publishing LLC. Source

Leong W.L.,National University of Singapore | Vittal J.J.,Gyeongsang National University
Chemical Reviews | Year: 2011

Complexity and diversity in structures, properties, and applications are examined. Zigzag type conformation is also ubiquitous in 1D CPs. The construction of zigzag CPs stemmed from flexible exoditopic ligands and linear or cis-coordinated octahedral metal centers or tetrahedral metal ions. Infinite helical structural motif has special place in supramolecular chemistry because of its similarities in biological systems and enantioselective catalysis. Generally, utilization of flexible or chiral ligands is a facile approach to achieve helical CPs, while many successful examples of spontaneous chirality induction from achiral ligands also have been widespread in the literature. Conformationally flexible ligands are the key success of self-assembly of structural motifs, such as polycatenanes, helices, braids, Borromean rings and rotaxanes. Source

Kole G.K.,National University of Singapore | Vittal J.J.,National University of Singapore | Vittal J.J.,Gyeongsang National University
Chemical Society Reviews | Year: 2013

This tutorial review discusses recent literature on coordination polymers and metal-organic frameworks (MOFs) that exhibit solid-state reactivity and structural transformation under various experimental conditions. Removal or exchange of solvents and guest molecules, exposure to reactive vapours, and external stimuli such as heat, light or mechanochemical force cause such structural transformations and these are often manifested by various physical properties such as colour, magnetism, luminescence, chirality, porosity, etc. due to change in coordination number and geometry, dimensionality, interpenetration, etc. More drastic transformations related to the exchange of metal ions, pillar ligands and insertion of additional ligands between the layers have also been demonstrated. The vast area of dynamic behaviour of coordination polymers and their stimuli-responsive properties have also been addressed briefly. © 2013 The Royal Society of Chemistry. Source

Koh P.-O.,Gyeongsang National University
Journal of Pineal Research | Year: 2012

Melatonin is an antioxidant that has neuroprotective functions in ischemic brain injury. Protein phosphatase 2A (PP2A) is a serine and threonine phosphatase that modulates cell metabolism and cell survival. This study investigated whether melatonin modulates PP2A subunit B in focal cerebral ischemia and glutamate toxicity-induced neuronal cell death in a rat model. Middle cerebral artery occlusion (MCAO) was performed to induce permanent cerebral ischemic injury. Adult male rats were treated with vehicle or melatonin (5 mg/kg) prior to MCAO, and cerebral cortex tissues were collected 24 hr after MCAO. A proteomic approach elucidated the decrease in PP2A subunit B in MCAO-operated animals. Melatonin treatment attenuated injury-induced reductions in PP2A subunit B levels. Western blot analyses indicated that melatonin prevents injury-induced decrease in PP2A subunit B levels. In neuronal cells, glutamate toxicity induced a lowering of PP2A subunit B, while melatonin treatment attenuated the glutamate exposure-induced decreases in PP2A subunit B. These results suggest that the maintenance of PP2A subunit B by melatonin in ischemic injury is critical to the neuroprotective function of melatonin during neuronal cell damage. © 2011 John Wiley & Sons A/S. Source

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