Chinju, South Korea

Gyeongsang National University

eng.gnu.ac.kr/
Chinju, South Korea

Gyeongsang National University is a national university governed under the ministry of education of Republic of Korea government and located in Jinju, South Gyeongsang Province and represents the South Gyeongsang Province of South Korea as one of 10 Flagship Korean National Universities along with Cheju National University, Chonbuk National University, Chonnam National University, Chungnam National University, Chungbuk National University, Kangwon National University, Kyungpook National University, Pusan National University, and Seoul National University.Gyoengsang National University has twelve colleges including arts, social science, natural science, engineering, agriculture and life science, management, veterinary, education, nursing, and medicine and eight graduate schools including medicine and public health, business administration, education, aerospace, industry etc. Other institutions with the university are the university library, the university museum, student center, university newspaper and broadcasting center, publishing company, institute for education of science talented, Korean language cultural center and so on. The current statistics of Gyeongsang National University shows that it has 1,681 academic staffs including 808 full-time professors, 361 administrative staffs and 24,502 students including undergraduate and graduate students enrolled. The university has three campuses and two of these are located in Jinju, South Gyeongsang Province and the other is located in Tongyeong. The main campus is located at Gajwa in the city of Jinju, Chilam campus, Jinju has the college of medicine, and Tongyeong campus, an hour from Jinju by car, has the college of Marine Science.The motto of Gyeongsang National University is Pioneer and it states that the eyes of pioneers see far beyond the present to the future. The history of the university begun as Jinju Agricultural College founded in Jinju in 1948, in 1968, accredited as national college and in 1972, renamed as Gyeongsang National College. In 1980, it was accredited as national university by the ministry of education and renamed as Gyeongsang National University. For more than 60 years since its foundation, Gyeongsang National University has been educating talented students who have served not only for local community but also for national prosperity by leading them to be bigger asset in many places such as communities, industries, businesses and so on around the country and the world.Gyeongsang National University is well known for many achievements in applied life science along with biochemistry, agricultural science, and veterinary. One of these is that the researchers at the university discovered a way to make cloned Turkish Angora cats glow red when exposed to ultraviolet light in 2007 and many alumni in these fields are working as researchers and professionals in research institutions and universities around the world. In present, the university has made its highly competitive fields of study broad to mechanical and aerospace systems engineering and new nano-materials engineering. In addition, Gyeongsang National University has made achievements in humanities and in sociology, two fields which lay the foundation for human ethics. Beside this, Gyeongsang National University is proud to have the college of Education in where great middle school teachers are educated to take responsibility for education of Republic of Korea, the college of Veterinary Medicine in where international veterinarians are trained, and the College of Marine Science to pioneer the studies of the ocean in the twenty first century. The university keeps moving on to provide advanced international education in Republic of Korea by successfully partnering in international campuses in Incheon as well as Busan-Jinhae Free Economic Zones.The Graduate School of Medicine and Public Health at Gyeongsang National University is unique medical training and research institution in South Gyeongsang Province and plans are being made with Gyeongsang National University Hospital to open a specialized medical center in the city of Changwon as the second Gyeongsang National University hospital in 2013. Gyeongsang National University Hospital opened with 419 beds in 1987 as the university hospital of Gyeongsang National University and is located next to the college of medicine in Chilam campus and has provided health care service with quality for more than 25 years and grown to a general and multispecialty medical hospital with 950 beds operating with specialty centers such as the local cancer center opened as the first local cancer center of its kinds in the country and rheumatoid arthritis center. Wikipedia.

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Patent
Gyeongsang National University | Date: 2017-01-31

A quadruple mutant (qm) plant is deficient of functions of core 1,3-fucosyltransferase A (FucTA), core 1,3-fucosyltransferase B (FucTB), 1,2-xylosyltransferase (XylT), and 1,2-N-acetylglucosaminyltransferase II (GnTII), and produces a protein containing hypoallergenic pauci-mannose-type N-glycan that does not include 1,3-fucose and 1,2-xylose residues. A method for producing a transgenic plant for a production of a protein containing hypoallergenic pauci-mannose-type N-glycan that does not include 1,3-fucose and 1,2-xylose residues but includes 1,6-fucose residue includes preparing the quadruple mutant (qm) plant, and transforming the quadruple mutant plant with a recombinant vector containing a gene encoding the human-derived 1,6-fucosyltransferase (FUT8) protein to overexpress FUT8 gene, and selecting a transgenic plant which is deficient of the functions of FucTA, FucTB, XylT and GnTII proteins.


Patent
Samsung and Gyeongsang National University | Date: 2017-01-25

Provided are a carbazole-based compound and an organic light-emitting device including the same. The carbazole-based compound may have the following general structure: wherein details and examples of L_(1 )through L_(6), R_(1 )through R_(6), a_(1 )through a_(6), and b_(1 )through b_(6 )are provided.


The present invention relates to a device for imaging and diagnosing the condition of obstruction of the upper airway, which can image the condition of a change in the upper airway of an OSAS patient occurring during natural sleep by using EIT and can extract information required for diagnosis. The device for imaging and diagnosing the condition of obstruction of the upper airway by using EIT according to the present invention does not require high costs, enables repeated examination to be conducted without the risk of exposure to radioactive rays, and enables examination to be performed over a prolonged period of time in an actual natural sleep state, thereby accurately diagnosing the condition of obstruction of the upper airway.


Patent
Samsung and Gyeongsang National University | Date: 2016-09-12

An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer includes at least one condensed cyclic compound of Formula 1: An organic light-emitting device including the condensed cyclic compound according to embodiments of the present disclosure may have low driving voltage, high efficiency, high luminance, and long lifespan.


The present invention relates to a device for imaging and diagnosing the condition of obstruction of the upper airway, which can image the condition of a change in the upper airway of an OSAS patient occurring during natural sleep by using EIT and can extract information required for diagnosis. The device for imaging and diagnosing the condition of obstruction of the upper airway by using EIT according to the present invention does not require high costs, enables repeated examination to be conducted without the risk of exposure to radioactive rays, and enables examination to be performed over a prolonged period of time in an actual natural sleep state, thereby accurately diagnosing the condition of obstruction of the upper airway.


Patent
Gyeongsang National University | Date: 2017-10-11

The present invention relates to a wheel assembly that is a chassis of a vehicle, and more particularly, to a vehicular composite wheel fastening structure in which a vehicular wheel assembly is formed of a fiber-reinforced composite and a connection portion structure of a composite wheel including a spoke portion and a rim portion is simplified to enable automated fabrication.


Koh P..-O.,Gyeongsang National University
Synapse | Year: 2013

Intracellular calcium overload is a critical pathophysiological factor in ischemic injury. Hippocalcin is a neuronal calcium sensor protein that buffers intracellular calcium levels and protects cells from apoptotic stimuli. Ferulic acid exerts a neuroprotective effect in cerebral ischemia through its anti-oxidant and anti-inflammation activity. This study investigated whether ferulic acid contributes to hippocalcin expression during cerebral ischemia and glutamate exposure-induced neuronal cell death. Rats were immediately treated with vehicle or ferulic acid (100 mg/kg, i.v.) after middle cerebral artery occlusion (MCAO). Brain tissues were collected 24 h after MCAO and followed by assessment of cerebral infarct. Ferulic acid reduced MCAO-induced infarct regions. A proteomics approach elucidated a decrease in hippocalcin in MCAO-operated animals, ferulic acid attenuates the injury-induced decrease in hippocalcin expression. Reverse transcription-polymerase chain reaction and Western blot analyses confirmed that ferulic acid prevents the injury-induced decrease in hippocalcin. In cultured HT22 hippocampal cells, glutamate exposure increased the intracellular Ca2+ levels, whereas ferulic acid attenuated this increase. Moreover, ferulic acid attenuated the glutamate toxicity-induced decrease in hippocalcin expression. These findings can suggest the possibility that ferulic acid exerts a neuroprotective effect through modulating hippocalcine expression and regulating intracellular calcium levels. Synapse 67:390-398, 2013.© 2013 Wiley Periodicals, Inc..


Koh P.-O.,Gyeongsang National University
Neuroscience Letters | Year: 2015

Ferulic acid provides neuroprotective effects against a middle cerebral artery occlusion (MCAO)-induced cerebral ischemia. Mitogen-activated protein kinases can regulate extensive intracellular processes including cell differentiation, growth, and death. This study further investigated whether ferulic acid modulates a protective mechanism through the activation of Raf-MEK-ERK and its downstream targets, including 90 ribosomal S6 kinase (p90RSK) and Bad during cerebral ischemic injury. Male Sprague-Dawley rats were treated with ferulic acid (100. mg/kg) or vehicle after the onset of MCAO and brain tissues were collected 24. h after MCAO. These results indicated that ferulic acid decreases the volume of the infarct area and the number of cells positive in terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) staining. Although MCAO injury induces a decrease in the phosphorylation of Raf-1, MEK1/2, and ERK1/2, ferulic acid treatment prevents the injury-induced decrease in these phosphorylation levels. Ferulic acid also attenuates the injury-induced decrease in p90RSK and Bad phosphorylation levels. These findings suggest that ferulic acid prevents MCAO-induced neuronal cell death and that the MEK-ERK-p90RSK-Bad signaling pathway is involved in these neuroprotective effects. © 2014 Elsevier Ireland Ltd.


Koh P.-O.,Gyeongsang National University
Neuroscience Letters | Year: 2012

Ferulic acid protects neuronal cells from glutamate-induced excitotoxicity and focal cerebral ischemia. This study investigated whether ferulic acid exerts a neuroprotective effect through the activation of Akt and its downstream targets, Bad and 14-3-3. Adult male rats were immediately treated with ferulic acid (100. mg/kg, i.v.) after middle cerebral artery occlusion (MCAO). Brains were collected 24. h after MCAO and infarct volumes were analyzed using triphenyltetrazolium chloride staining. It was found that ferulic acid treatment significantly reduced infarct volume during MCAO. Ferulic acid attenuated the MCAO injury-induced decrease of phospho-PDK1, phospho-Akt and phospho-Bad levels. However, ferulic acid did not affect the expression of 14-3-3 and Bcl-xL, which exerts an anti-apoptotic effect through interaction with phospho-Bad. Immunoprecipitation analysis demonstrated that the interaction between phospho-Bad and 14-3-3 decreased during MCAO, whereas ferulic acid prevented the injury-induced decrease in these interaction levels. Moreover, ferulic acid prevented the injury-induced increase in cleaved caspase-3 levels. These findings suggest that ferulic acid attenuates cell death during MCAO and that these protective effects are due to inhibition of Akt signaling pathway inactivation and maintenance of the interaction between phospho-Bad and 14-3-3. © 2011 Elsevier Ireland Ltd.


Leong W.L.,National University of Singapore | Vittal J.J.,Gyeongsang National University
Chemical Reviews | Year: 2011

Complexity and diversity in structures, properties, and applications are examined. Zigzag type conformation is also ubiquitous in 1D CPs. The construction of zigzag CPs stemmed from flexible exoditopic ligands and linear or cis-coordinated octahedral metal centers or tetrahedral metal ions. Infinite helical structural motif has special place in supramolecular chemistry because of its similarities in biological systems and enantioselective catalysis. Generally, utilization of flexible or chiral ligands is a facile approach to achieve helical CPs, while many successful examples of spontaneous chirality induction from achiral ligands also have been widespread in the literature. Conformationally flexible ligands are the key success of self-assembly of structural motifs, such as polycatenanes, helices, braids, Borromean rings and rotaxanes.

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