Gyeongbuk Provincial College

Yecheon, South Korea

Gyeongbuk Provincial College

Yecheon, South Korea
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Park M.A.,Ellead Sin and Bio Research | Sim M.J.,Gyeongbuk Provincial College | Kim Y.C.,Keimyung University
Toxicological Research | Year: 2017

The effects that ultraviolet rays elicit on collagen synthesis and degradation are the most common causes of wrinkle formation and photo-aging in skin. The objectives of this study were to evaluate the effects of Angelica acutiloba root ethanol extract (AAEE) to promote collagen synthesis and inhibit collagen degradation in human dermal fibroblasts. By examining total polyphenol and flavonoid contents, electron donating ability, radical scavenging activity, and superoxide dismutase-like activity, we found that AAEE exhibited fairly good antioxidant activity. Treatment with AAEE significantly increased type I procollagen production by cultured fibroblasts, as well as reduced ultraviolet-induced matrix metalloproteinase-1 (MMP-1) expression and MMP-2 activity in a dose-dependent manner (p < 0.05). In addition, AAEE significantly increased TIMP-1 mRNA expression (p < 0.05), although without an associated dose-dependent increase in TIMP-1 protein expression. In summary, we suggest that AAEE may be a potentially effective agent for the prevention or alleviation of skin-wrinkle formation induced by ultraviolet rays.


PubMed | Gyeongbuk Provincial College, Seoul National University of Science and Technology and Yeungnam University
Type: Journal Article | Journal: Asian-Australasian journal of animal sciences | Year: 2014

The thyroid hormone responsive protein (THRSP) gene is a functional gene that can be used to indicate the fatty acid compositions. This study investigates the relationships of exonic single nucleotide polymorphisms (SNPs) in the THRSP gene and fatty acid composition of muscle fat and marbling score in the 612 Korean cattle. The relationships between fatty acid composition and eight SNPs in the THRSP gene (g.78 G>A, g.173 C>T, g.184 C>T, g.190 C>A, g.194 C>T, g.277 C>G, g.283 T>G and g.290 T>G) were investigated, and according to the results, two SNPs (g.78 G>A and g.184 C>T) in exon 1 were associated with fatty acid composition. The GG and CC genotypes of g.78 G>A and g.184 C>T had higher unsaturated fatty acid (UFA) and monounsaturated fatty acid (MUFA) content (p<0.05). In addition, the ht1*ht1 group (Val/Ala haplotype) in a linkage disequilibrium increased MUFAs and marbling scores for carcass traits (p<0.05). As a result, g.78 G>A and g.184 C>T had significantly relationships with UFAs and MUFAs. Two SNPs in the THRSP gene affected fatty acid composition, suggesting that GG and CC genotypes and the ht1*ht1 group (Val/Ala haplotype) can be markers to genetically improve the quality and flavor of beef.


PubMed | Daejeon University, Korea Institute of Science and Technology, Halla University, GyeongBuk Provincial College and 5 more.
Type: | Journal: The Journal of investigative dermatology | Year: 2015

T cell-mediated immune responses play an important role in body protection. However, aberrantly activated immune responses are responsible for inflammatory and autoimmune diseases. The regulation of pathological immune responses may be a potential therapeutic strategy for the treatment of these diseases. Despite multiple pharmacological properties of benzoxathiole derivatives have been defined, the molecular mechanisms underlying these properties remain to be clarified. Here, we demonstrated the benzoxathiole derivative 2-cyclohexylimino-6-methyl-6,7-dihydro-5H-benzo[1,3]oxathiol-4-one (BOT-4-one) regulated immune responses and ameliorated experimentally induced inflammatory skin diseases both in vitro and in vivo. BOT-4-one inhibited the differentiation of CD4


Kim S.,Gyeongbuk Provincial College | Lee J.,Gyeongbuk Provincial College | Park S.,Sejong University
Turkish Journal of Veterinary and Animal Sciences | Year: 2016

The effect of dietary full-fat soybean on performance and carcass characteristics of Hanwoo steers was investigated. Thirty steers (653 ± 52.96 kg) were allotted to control and full-fat soybean groups with a 210-day comparative feedlot trial. Steers were fed either the basal finishing diet (control) or control plus 5% full-fat soybean, using Calan gates for individual intake measurement. There was no difference in BW, feed intake, carcass weight, backfat thickness, loin muscle area, or meat color between groups. The average daily gain was greater (P < 0.05) in the soybean group compared to the control group. Steers fed soybean showed a lower feed conversion ratio than the controls. Marbling in the soybean group was greater (P < 0.05) than that in the control group. Supplementary full-fat soybean increased (P < 0.05) crude fat but decreased (P < 0.05) crude protein content in the longissimus muscle. Full-fat soybean increased (P < 0.05) total unsaturated fatty acids, including the levels of oleic, linoleic, and linolenic acid but, consequently, decreased (P < 0.05) total saturated fatty acids. Levels of conjugated linoleic acid, and its major precursor trans-vaccenic acid, were significantly increased by soybean supplementation. Our results demonstrate that full-fat soybeans may offer a better way to produce healthier beef with increased unsaturated fatty acids. © TÜBÏTAK.


Kim B.M.,GyeongBuk Provincial College | Hwang K.-P.,Samsung | Cho Y.K.,Kyungpook National University
IEEE Antennas and Propagation Society, AP-S International Symposium (Digest) | Year: 2011

In this paper, a small planar bow-tie antenna fed by a flanged rectangular waveguide is investigated using the finite element method (FEM). The bow-tie antenna has two triangular conductive strips separated by a gap and each strip has an inverted triangular hole. Numerical results show that this bow-tie antenna can generate intense electrical field spots below the diffraction limit with transmission efficiency approaching unity. Antenna characteristics of the bow-tie antenna with holes are compared with those of the bow-tie antenna without holes as well as the flanged rectangular waveguide feed only. © 2011 IEEE.


Kim B.-M.,Gyeongbuk Provincial College | Son H.-W.,Kyungpook National University | Cho Y.-K.,Kyungpook National University | Hong J.-P.,Kyungil University
Journal of the Korean Physical Society | Year: 2014

We present a simple method for efficient modeling of the tunneling effect in an Epsilon Near Zero (ENZ) channel waveguide based on a transmission-line model. The proposed ENZ channel uses a double-ridge rectangular waveguide (RWG) and is located in the middle of the input-output standard rectangular waveguides (IORWG). The height of the channel waveguide is much smaller than that of the IORWG. The detailed design of the ENZ channel is presented, and the optimum length for tunneling phenomena is calculated. These theoretical studies highlight the substantial differences between this unique tunneling phenomenon and higher-frequency Fabry-Perot resonances. We perform a simulation for the designed ENZ channel by using a commercial FEM simulator. The simulated and the measured results for the fabricated ENZ channel structure are in good agreement. © 2014, The Korean Physical Society.


Lee C.H.,Kyungpook National University | Cho Y.K.,Kyungpook National University | Kim B.M.,GyeongBuk Provincial College
2015 International Workshop on Antenna Technology, iWAT 2015 | Year: 2015

The wavelength shift of transmission resonance was achieved by a tapered metallic slit. We simulated the transmission and reflection of the tapered slit structure with the tapered slit width of 0.25, 0.5, 0.75 and 1 mm. The tapered slit angle shifted higher the resonance frequency, by which the cavity resonant length became shorter. © 2015 IEEE.


Hong S.H.,Korea University | Sim M.J.,Gyeongbuk Provincial College | Kim Y.C.,Keimyung University
Toxicological Research | Year: 2016

We evaluated the antioxidant activity and melanogenic effects of black soybean ethanol extracts, including Rhynchosia nulubilis bean ethanol extract (RNBEE), R. nulubilis leaf ethanol extract (RNLEE), R. volubilis bean ethanol extract (RVBEE), and R. volubilis leaf ethanol extract (RVLEE). The total polyphenol contents of RNBEE, RNLEE, RVBEE, and RVLEE were 16.0, 57.7, 365.9, and 260.1 mg/g, respectively. The total flavonoid contents of RNBEE, RNLEE, RVBEE, and RVLEE were 40.4, 91.7, 84.7, and 216.5 mg/g, respectively. The electron-donating abilities of RNBEE, RNLEE, RVBEE, and RVLEE at 1,000 μg/ mL were 32.4%, 12.7%, 83.5%, and 84.5%, respectively. RNBEE, RNLEE, RVBEE, and RVLEE at 50 μg/ mL significantly increased (p < 0.01) melanin contents by 30.4%, 32.1%, 35.5%, and 37.4%, respectively, compared to that of the control. RNBEE, RNLEE, RVBEE, and RVLEE at 50 μg/mL significantly increased (p < 0.01) intracellular tyrosinase activity by 18.4%, 21.8%, 21.5%, and 21.1%, respectively, compared to that of the control. These results demonstrated that black soybean ethanol extracts promote melanogenesis in melan-a cells. Among the black soybean ethanol extracts, R. volubilis was found to be more effective than R. nulubilis, and leaf extract was found to be more effective than bean extract. The potential mechanism underlying the hyperpigmentation effects of black soybeans is the promotion of tyrosinase activity.


PubMed | Keimyung University, Korea University and Gyeongbuk Provincial College
Type: Journal Article | Journal: Toxicological research | Year: 2016

We evaluated the antioxidant activity and melanogenic effects of black soybean ethanol extracts, including Rhynchosia nulubilis bean ethanol extract (RNBEE), R. nulubilis leaf ethanol extract (RNLEE), R. volubilis bean ethanol extract (RVBEE), and R. volubilis leaf ethanol extract (RVLEE). The total polyphenol contents of RNBEE, RNLEE, RVBEE, and RVLEE were 16.0, 57.7, 365.9, and 260.1 mg/g, respectively. The total flavonoid contents of RNBEE, RNLEE, RVBEE, and RVLEE were 40.4, 91.7, 84.7, and 216.5 mg/g, respectively. The electron-donating abilities of RNBEE, RNLEE, RVBEE, and RVLEE at 1,000 g/mL were 32.4%, 12.7%, 83.5%, and 84.5%, respectively. RNBEE, RNLEE, RVBEE, and RVLEE at 50 g/mL significantly increased (p < 0.01) melanin contents by 30.4%, 32.1%, 35.5%, and 37.4%, respectively, compared to that of the control. RNBEE, RNLEE, RVBEE, and RVLEE at 50 g/mL significantly increased (p < 0.01) intracellular tyrosinase activity by 18.4%, 21.8%, 21.5%, and 21.1%, respectively, compared to that of the control. These results demonstrated that black soybean ethanol extracts promote melanogenesis in melan-a cells. Among the black soybean ethanol extracts, R. volubilis was found to be more effective than R. nulubilis, and leaf extract was found to be more effective than bean extract. The potential mechanism underlying the hyperpigmentation effects of black soybeans is the promotion of tyrosinase activity.


PubMed | Woosung Feed Co., Yeungnam University and Gyeongbuk Provincial College
Type: Journal Article | Journal: Asian-Australasian journal of animal sciences | Year: 2016

This study was conducted to evaluate the effect of dietary supplementation with rice bran, flax seed, or sunflower seed to finishing native Korean cattle (Hanwoo) on growth performances, carcass characteristics, fatty acid composition, free amino acid and peptide contents, and sensory evaluations of Longissimus muscle (LM). A total of 39 Hanwoo steers (average age of 22.2 mo and average body weight (BW) of 552.2 kg) were randomly divided into Control, rice bran (RB), flax seed (FS), or Sunflower seed (SS) groups. The steers were group fed for 273 d until they reached an average age of 31.2 mo. Final BW was 768.2, 785.8, 786.2, and 789.0 kg, and average daily gain was 0.79, 0.85, 0.82, and 0.84 kg for the Control, RS, FS, and SS groups, respectively (p>0.05). Fat thickness of the FS group (19.8 mm) was greater (p<0.05) than that of the other groups. Final yield grade converted into numerical values was 2.0 for the RB group, 1.7 for the Control and SS groups, and 1.4 for the FS group. Marbling degrees for the Control, SS, RB, and FS groups were 5.3, 5.1, 4.7, and 4.6, respectively. Percentages of palmitic acid (C16:0), stearic acid (C18:0), and arachidic acid (C20:0) in the LM were not different among the groups. Palmitoleic (C16:1) acid was higher (p<0.05) in the SS group. The concentration of oleic acid was highest (p<0.05) in the Control group (47.73%). The level of linolenic acid (C18:3) was 2.3 times higher (p<0.05) in the FS group compared to the other groups. Methionine concentration was (p<0.05) higher in FS (1.7 mg/100 g) and SS (1.2 mg/100 g) steers than in the Control or RB groups. Glutamic acid and -aminoadipic acid (-AAA) contents were (p<0.05) higher in the FS group compared to the other groups. LM from the FS group had numerically higher (p>0.05) scores for flavor, umami, and overall palatability in sensory evaluations. In conclusion, supplementation of flax seed to diets of finishing Hanwoo steers improved sensory evaluations which might have been caused by increases in flavor related amino acids such as methionine, glutamic acid and -AAA and peptides, anserine and carnosine, and their complex reactions.

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