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Hisar, India

Guru Jambheshwar University of Science and Technology, Hisar, was founded in 1995. The jurisdiction of the university extends to the courses being run in the areas of science, technology, engineering, pharmacy and management. Wikipedia.

Bansal N.,Guru Jambheshwar University of Science and Technology
Journal of medicinal food | Year: 2010

Phytoestrogens are nonsteroidal plant compounds that are able to exert estrogenic effects. Soybean is a rich source of phytoestrogens, especially isoflavones. Soy isoflavones are utilized for estrogen replacement therapy. Estrogen is reported to influence several areas of brain that are involved in cognition and behavior. Therefore, the present study was undertaken to examine whether dietary supplementation with soybean improves the cognitive function of mice. Soybean was administered in three different concentrations (2%, 5% and 10% [wt/wt]) in the normal diet to young and mature mice for 60 successive days. The passive avoidance paradigm and the elevated plus maze served as the exteroceptive behavioral models, whereas scopolamine (1.4 mg/kg, i.p.) served as the interoceptive behavioral model. The brain acetylcholinesterase activity (AChE) activity, brain thiobarbituric acid-reactive substances (TBARS), reduced glutathione (GSH), and total blood cholesterol levels were also measured in the present study. The administration of soybean for 60 consecutive days protected (P <.05) the animals from developing memory impairment. Soybean administration also resulted in diminished brain AChE activity, decrease in brain TBARS, and increase in GSH levels, thereby indicating facilitated cholinergic transmission, reduced free radical generation, and enhanced scavenging of free radicals. Thus, soybean appears to be a useful remedy for improving memory and for the management of cognitive deficits owing to its pro-estrogenic, antioxidant, procholinergic, and/or neuroprotective properties.

Jain M.,Guru Jambheshwar University of Science and Technology | Garg V.K.,Guru Jambheshwar University of Science and Technology | Kadirvelu K.,Bharathiar University
Bioresource Technology | Year: 2013

The present study reports the use of sunflower waste carbon calcium-alginate beads (SWC-CAB) for cadmium removal from wastewater in continuous flow fixed bed columns. The experiments were conducted as a function of bed height, flow rate and initial Cd(II) concentration. The maximum biosorption capacity (23.6mg/g) was attained at 30cm bed height, 1.0mL/min flow rate and 10mg/L initial Cd(II) concentration. The Bohart - Adams model constants (N0 and K) were 7.7mg/L and 1×10-4L/mgh with 0.999 R2 value at 50% breakthrough time. The column regeneration efficiency after third cycle was 58.6% for cadmium. © 2012 Elsevier Ltd.

Yadav A.,Guru Jambheshwar University of Science and Technology | Garg V.K.,Guru Jambheshwar University of Science and Technology
Bioresource Technology | Year: 2011

This study reports the results of vermicomposting with Eisenia fetida of Parthenium hysterophorus mixed with cow dung in different ratios (25%, 50% and 75%) in a 18weeks experiment. In all the treatments, a decrease in pH, OC total and C:N ratio, but increase in EC, N total, P aval, Ca total, K total and heavy metals was recorded. The cocoons production and growth rate (biomass gain worm -1 day -1) were maximum in 100% cow dung. The results indicated that parthenium can be a raw material for vermicomposting if mix with cow dung in appropriate quantity. © 2011 Elsevier Ltd.

Singh A.,Guru Jambheshwar University of Science and Technology | Bishnoi N.R.,Guru Jambheshwar University of Science and Technology
Applied Microbiology and Biotechnology | Year: 2012

Cellulase, Tween 80, and β-glucosidase loading were studied and optimized by response surface methodology to improve saccharification. Microwave alkali-pretreated rice straw used as substrate for onsite enzyme production by Aspergillus heteromorphus and Trichoderma reesei. The highest enzymatic hydrolysis (84%) was obtained from rice straw at crude enzyme loading of 10 FPU/gds of cellulase, 0.15% Tween 80, and 100 international unit/g dry solids of β-glucosidase activities. Enzymatic hydrolyzate of pretreated rice straw was used for ethanol production by Saccharomyces cerevisiae, Scheffersomyces stipitis, and by co-culture of both. The yield of ethanol was 0.50, 0.47, and 0.48 g p/g s by S. cerevisiae, S. stipitis, and by co-culture, respectively, using pretreated rice straw hydrolyzate. The co-culture of S. cerevisiae and S. stipitis produced 25% more ethanol than S. cerevisiae alone and 31% more ethanol than S. stipitis alone. During anaerobic fermentation 65.08, 36.45, and 50.31 μmol/ml CO 2 released by S. cerevisiae, S. stipitis, and by co-culture, respectively. The data indicated that saccharification efficiency using optimized crude enzyme cocktail was good, and enzymatic hydrolyzate could be fermented to produce ethanol. © 2012 Springer-Verlag.

Sharma R.,Guru Jambheshwar University of Science and Technology | Ahuja M.,Guru Jambheshwar University of Science and Technology
Carbohydrate Polymers | Year: 2011

The objective of present study was to enhance mucoadhesive potential of pectin by thiolation. Thiolation of pectin was achieved with esterification with thioglycolic acid. Thiolated pectin was characterized by FTIR, DSC, XRD and SEM analysis. Thiolated pectin was determined to possess 0.60 ± 0.04 mmol of thiol groups/g of polymer by Ellman's method. Comparative evaluation of mucoadhesive property of metformin-loaded ionotropically gelled beads of pectin and thiolated pectin by wash off test using goat intestinal mucosa revealed higher ex vivo bioadhesion time of thiolated pectin as compared to pectin. Improved mucoadhesive property of thiolated pectin over the pectin can be attributed to the formation of disulfide bond between mucus and thiolated pectin. In vitro release study conducted using phosphate buffer (pH 6.8) revealed a similar release profile of metformin from pectin and thiolated pectin beads. In conclusion, thiolation of pectin improves its mucoadhesive property without affecting the release profile. © 2011 Elsevier Ltd. All rights reserved.

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