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Bilaspur, India

Guru Ghasidas Vishwavidyalaya , is a Central University of India, located in Bilaspur C.G. State, established under Central Universities Act 2009, No. 25 of 2009. Formerly called Guru Ghasidas University , established by an Act of the State Legislative Assembly, was formally inaugurated on June 16, 1983. GGU is an active member of the Association of Indian Universities and Association of Commonwealth Universities. The National Assessment & Accreditation Council has accredited the University as B+ . Situated in a socially and economically challenged area, the university is appropriately named to honor the great Satnami Saint Guru Ghasidas , who championed the cause of the downtrodden and waged a relentless struggle against all forms of social evils and injustice prevailing in the society.The University is a residential cum affiliating institution, having its jurisdiction spread over Bilaspur Revenue Division of the state of Chhattisgarh. Guru Ghasidas University was formally inaugurated on June 16, 1983 and is one of the two universities in Chhattisgarh State, India. It is in Bilaspur. It was named after Guru Ghasidas, the founder of the Satnami movement in the region. The jurisdiction of the university is spread across the Bilaspur Revenue Division. It covers almost the entire spectrum of the higher education requirements of the local people. It has several University Teaching Department on its campuses. The university is a residential cum affiliating institution. Wikipedia.

Prajapati R.P.,Guru Ghasidas University
Physics Letters, Section A: General, Atomic and Solid State Physics | Year: 2013

The Jeans instability of self-gravitating dusty plasma with polarization force is investigated considering the effects of magnetic field, dust temperature and radiative condensation. The condition of Jeans instability and expression of critical Jeans wave number are obtained which depend upon polarization force and dust temperature but these are unaffected by the presence of magnetic field. The radiative heat-loss functions also modify the Jeans condition of instability and expression of critical Jeans wave number. It is observed that the polarization force and ratio of radiative heat-loss functions have destabilizing while magnetic field and dust temperature have stabilizing influence on the growth rate of Jeans instability. © 2012 Elsevier B.V. All rights reserved.

Dispersive liquid-liquid microextraction (DLLME) is applied for the determination of copper in cereals and vegetable food samples using flame atomic absorption spectrometry (FAAS). The maximum extraction efficiency of copper was obtained after the optimisation of parameters such as extraction and dispersing solvents, pH, concentration of 2,9-dimethyl-1,10-phenanothroline (DPT), N-phenylbenzimidoyl thiourea (PBITU) and salt. The optimised methodology exhibited a good linearity in the range of 0.2- 20 ng/mL copper with relative standard deviations percentage (RSD,%) from ±1.5% to 3.5%. The method is found to be simple and rapid for the analysis of copper in food samples with the limit of detection (LOD) and quantitation (LOQ) were 0.05 and 0.16 ng/mL, respectively. Good recoveries of copper were obtained in the range of 93.5-98.0% in food samples as well as in Certified Reference Material (99.1%). The application of the proposed method has been successfully tested for the determination of copper in cereals (maize, millet, rice, wheat, gram, lentils, kidney beans and green beans) and vegetable (potato, cauliflower, tomato, spinach, green beans, lettuce, egg plants and bitter gourd) food samples. © 2013 Elsevier Ltd. All rights reserved.

Jain P.,Guru Ghasidas University
Natural Product Research | Year: 2016

Peptic ulcers are open sores or erosions in the lining of either the duodenum (duodenal ulcers) or the stomach (gastric ulcers). Peptic ulcer, which is mainly caused by bacterial attack or excess of acid secretion, can be cured effectively by these isolated plant compounds. In this present scenario, demand for herbal medicines are increasing due to easy availability in surrounding place at low cost. This review article is all about such isolated plant compounds such as alkaloids, flavonoids and terpenoids. Various plants have been used as folk medicine by the people of rural area, which shows significant effect against peptic ulcer. Further study should be conducted upon these herbal plants because there is possibility for minimising the adverse effect caused by the present antiulcer drugs. © 2015 Taylor and Francis.

Thareja S.,Guru Ghasidas University
Chemical Reviews | Year: 2015

Benign prostatic hyperplasia (BPH) is the noncancerous growth of the prostate gland due to over-proliferation of the stromal and glandular elements of the prostate, resulting in the obstruction of proximal urethra, thus causes urinary flow disturbances. It is caused due to the augmented levels of the androgen dihydrotestosterone (DHT), which plays a key role in prostate growth. In the absence of crystal structure and binding site information, the design of novel inhibitors using a rational designing approach is not possible. Therefore, inhibitors were designed by modifying the structure of natural substrates, including the substitution of one carbon atom of the rings of the steroids by a heteroatom such as nitrogen, thereby forming azasteroids. 2D-QSAR techniques are of particular interest as they eliminate the need for determining 3D structure, putative binding conformation, and molecular alignment.

Nayak A.K.,Seemanta Institute of Pharmaceutical science | Pal D.,Guru Ghasidas University
Carbohydrate Polymers | Year: 2014

Fenugreek (Trigonella foenum-graecum L.) seed mucilage (FSM)-gellan gum (GG) mucoadhesive beads containing metformin HCl for oral use were developed through ionotropic-gelation technique. Effects of GG to FSM ratio and cross-linker (CaCl2) concentration on the drug encapsulation efficiency (DEE, %), and cumulative drug release after 10 h (R10h, %) of ionotropically-gelled FSM-GG mucoadhesive beads containing metformin HCl were optimized by 32 factorial design. The optimized mucoadhesive beads showed DEE of 92.53 ± 3.85% and R10h of 55.28 ± 1.58% and mean diameter of 1.62 ± 0.22 mm. The in vitro metformin HCl release from these ionotropically-gelled FSM-GG beads was prolonged over 10 h and followed zero-order model with super case-II transport mechanism. The optimized mucoadhesive beads also exhibited pH-dependent swelling, good mucoadhesivity with biological mucosal membrane and significant hypoglycemic effect in alloxan-induced diabetic rats over prolonged period after oral administration. © 2014 Elsevier Ltd. All rights reserved.

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