Jamnagar, India
Jamnagar, India

Gujarat Ayurved University is located in Jamnagar, Gujarat, India. It is the first statutory university of its kind, both at national and international level, exclusively devoted to Ayurvedic studies and research. Wikipedia.


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Khedekar S.,Maharashtra University of Health Sciences | Rukkudin G.,Gujarat Ayurved University | Ravishankar B.,Center for Research in Ayurveda & Allied science | Prajapati P.,Gujarat Ayurved University
Journal of Intercultural Ethnopharmacology | Year: 2016

Background: Makaradhwaja a gold containing mercurial preparation used for diabetes mellitus in indigenous system of medicine. It is a popular aphrodisiac and rejuvenator traditional medicine. It is prepared by using processed gold, mercury and sulfur in different ratios by applying intermittent heating pattern in Valuka Yantra. Objectives: The aim of the study was to evaluate anti-diabetic effect of Shadguna Balijarita Makaradhwaja (SBM) on streptozotocin (STZ) induced diabetic rats. Materials and Methods: Diabetes was induced to normal rats by injecting STZ in dose 40 mg/kg. Powdered SBM and dried extract of Tinospora cordifolia were mixed with honey and administered orally for 20 days at dose 2.63 mg/kg and 42.34 mg/kg body weight, respectively. The effects of treatment on body weight changes and blood glucose levels were quantified on day 1, 5, 10, 15 and 21 of the experiments. On the 21st day, animals were sacrificed and gross histopathological changes in liver, kidney and pancreas were illustrated. Blood sugar level, glyacated hemoglobin, blood urea, serum cholesterol, serum creatinine, serum triglyceride and serum protein were estimated with standard methods. The study was conducted in the year 2011. Results: Test drug observed significant decrease (P < 0.001) in glyacated hemoglobin level compared to diabetic control rats. Blood sugar level of test drug group shown a significant decrease (279.11 ± 57.95) compared with diabetic rats. Conclusion: The present study demonstrates that SBM and dried extract of T. cordifolia with honey significantly reduces the blood glucose level and shows anti-diabetic effect. © SAGEYA.


Gupta V.,Ayurgenomics TRISUTRA Project | Rajagopala M.,Gujarat Ayurved University | Ravishankar B.,Center for Research in Ayurveda and Allied science
Indian Journal of Ophthalmology | Year: 2014

Natural eye lens is a crystalline substance to produce a clear passage for light. Cataract is opacity within the clear lens of the eye and is the dominant cause of socio-medical problem i.e., blindness worldwide. The only available treatment of cataract is surgery. However, insufficient surgical facilities in poor and developing countries and post-operative complications inspire researchers to find out other modes of treatment for cataract. In this review, an attempt has been made to appraise various etiological factors of cataract to make their perception clear to build up counterpart treatment. Present study is an assortment of various available literatures and electronic information in view of cataract etiopathogenesis. Various risk factors have been identified in development of cataracts. They can be classified in to genetic factors, ageing (systemic diseases, nutritional and trace metals deficiencies, smoking, oxidative stress etc.), traumatic, complicated (inflammatory and degenerative diseases of eye), metabolic (diabetes, galactosemia etc.), toxic substances including drugs abuses, alcohol etc., radiation (ultraviolet, electromagnetic waves etc.) are implicated as significant risk factors in the development of cataract.


Mitra S.,Gujarat Ayurved University
African journal of traditional, complementary, and alternative medicines : AJTCAM / African Networks on Ethnomedicines | Year: 2012

Strychnos nux vomica Linn.(Loganaceae) commonly known as Nux vomica (Kupeelu), is a poisonous plant and its seeds are used widely in Ayurvedic system of medicine since time immemorial. Ayurveda advocates that nux vomica seeds are to be administered in therapeutics only after going through certain purificatory measures (Shodhana). There are more than six media: cow's urine (Go mutra), cow's milk (Go dugdha), cow's ghee (Go ghrita), Kanji (thin gruel), castor oil (Eranda taila) and fresh ginger juice (Ardraka swarasa) etc., which have been reported in different classical texts of Ayurveda for proper processing of nux vomica seeds. In this study, an attempt has been made to purify the seeds by using three different methods as described in ancient treatise by using cow's urine and cow's milk as media alone and together. This study revealed that all the methods studied reduced the toxicity of strychnine and brucine contents in comparison to the raw seeds as determined by HPTLC. Out of these three methods maximum reduction in strychnine and brucine contents was found when the seeds were purified by keeping them in cow's urine for seven days followed by boiling in cow's milk for three hrs.


Mahanta V.,Gujarat Ayurved University | Dudhamal T.S.,Gujarat Ayurved University | Gupta S.K.,Gujarat Ayurved University
Journal of Ayurveda and Integrative Medicine | Year: 2013

Tennis elbow is a painful condition and causes restricted movement of forearm which requires treatment for long period. Till date only symptomatic treatments are available like use of anti-inflammatory analgesic drugs, steroids injection, physiotherapy, exercise etc. But none of these provide satisfactory result. Long term use of anti-inflammatory, analgesic drugs and steroids injection is also not free from the adverse effects. Usually, ′wait-and-see policy′ of treatment guideline is recommended in most of medical texts. According to Ayurveda, snayugata vata can be correlated with the condition of tennis elbow. Sushruta has advised Agnikarma for disorders of snayu (ligaments and tendons), asthi (bone), siddhi (joints) etc. Hence, in this study a case of tennis elbow (snayugata vata) was treated by Agnikarma, along with administration of powder of Ashwagandha and Navajivana Rasa orally, for a period of 03 weeks. This combination therapy provided considerable relief in pain and movement of the elbow joint.


Savrikar S.S.,Gujarat Ayurved University | Ravishankar B.,Gujarat University | Ravishankar B.,Center for Research in Ayurveda and Allied science
African Journal of Traditional, Complementary and Alternative Medicines | Year: 2011

The word Rasashaastra literally means the "Science of Mercury". It is a specialized branch of Ayurveda dealing mainly with materials which are known as 'Rasa dravyaas'. The products dealt under this discipline are an important component of Ayurvedic therapeutics. Considering the importance of this discipline in Ayurvedic therapeutics and the fact that there is dearth of comprehensive review on the subject an attempt has been made in this review to provide a brief but all encompassing coverage of different aspects related to it. The subjects covered in the review are: historical background of the evolvement of Rasashaastra as a specialized branch during different time periods; different aspects of classification 'Rasa dravyaas'; processing of metal and mineral products with a note on the methods used during different time periods; information about methods of pre and post preparation procedures for different kinds of 'Rasa dravyaas'; importance of mercury in Ayurveda, its processing methods and different preparations along with therapeutic indications. In addition attempt has been made to provide basic information on the metal and mineral based preparations mentioned in Ayurvedic Formulary of India; recent development in the field of Rasashaastra and future requirements for the proper development of the discipline. The main focus is to familiarize the readers, from non-ayurvedic background, on different aspects of this specialized discipline. © African Journal of Traditional, Complementary and Alternative Medicines.


Sharma H.,Ohio State University | Chandola H.M.,Gujarat Ayurved University
Journal of Alternative and Complementary Medicine | Year: 2011

Background: Obesity, metabolic syndrome, and diabetes mellitus are increasing in epidemic proportions globally. Prameha is a syndrome described in the ancient Ayurvedic texts that includes clinical conditions involved in obesity, prediabetes, diabetes mellitus, and metabolic syndrome. Materials and methods: Integrating the theory and modalities of Ayurveda in the management of these disorders may prove to be beneficial. Even though Prameha is a Tridoshaja Vyadhi (a disease involving all three of the psychophysiologic principles known as Doshas [i.e., Vata, Pitta, and Kapha]), it is basically a disease with Kapha predominance. Results: There are 20 subtypes of Prameha due to the interaction of the three Doshas and 10 Dushyas (disturbed functioning of the principles that support the various bodily tissues); several of these subtypes have sweet urine, whereas some of them have different coloration of the urine, highlighting the inflammatory conditions involved in the metabolic syndrome. This disease has close ties to Sthaulya (i.e., obesity). With regard to diabetes mellitus, Sahaja Prameha and Jatah Pramehi correlate with type 1 diabetes; Apathyanimittaja Prameha correlates with type 2 diabetes. Madhumeha is a subtype of Vataja Prameha (Prameha with Vata predominance) that can occur as the terminal stage of type 2 diabetes (in which insulin is required), or as type 1 diabetes beginning in early childhood. The latter is defined as Jatah Pramehi Madhumehino in Charaka Samhita, one of the classical Ayurvedic texts. Conclusions: Various dietary, lifestyle, and psychologic factors are involved in the etiology of Prameha, particularly in relation to disturbances in fat and carbohydrate metabolism. The ancient Ayurvedic knowledge regarding Prameha can be utilized to expand the current understanding of obesity, metabolic syndrome, and diabetes. © 2011 Mary Ann Liebert, Inc.


Sharma H.,Ohio State University | Chandola H.M.,Gujarat Ayurved University
Journal of Alternative and Complementary Medicine | Year: 2011

Obesity, metabolic syndrome, and diabetes mellitus are increasing to epidemic proportions globally. There are 400 million clinically obese adults worldwide and there are more than 220 million people who have diabetes. The global impact of these disorders is immense in terms of human suffering and economic burden. There is an urgent need for a more effective understanding of these disease processes and their management, including the use of natural strategies that are affordable and efficacious. The health care system known as Ayurveda has much to offer in this regard. Ayurveda describes a set of complex clinical disorders, collectively called Prameha, that are characterized by frequent abnormal micturition. The clinical conditions associated with Prameha correlate in many ways with obesity, metabolic syndrome, and diabetes mellitus. The etiology, classification, pathogenesis, and management of Prameha are discussed at length and in detail in the Ayurvedic texts. The theoretical background and comprehensive set of strategies Ayurveda utilizes to treat Prameha may be valuable in managing obesity, metabolic syndrome, and diabetes mellitus in an efficacious and cost-effective manner. © 2011 Mary Ann Liebert, Inc.


Savrikar S.S.,Gujarat Ayurved University | Ravishankar B.,Gujarat University
African Journal of Traditional, Complementary and Alternative Medicines | Year: 2010

In Ayurvedic therapeutics, drug therapy is given prime importance. There is a very well developed sub-discipline entirely devoted to drug formulations known as "Bhaisajya Kalpanaa". Considering its importance, different aspects of this discipline have been presented in this review to familiarize the readers, especially those who have just started studying Ayurveda, with concept of ayurvedic pharmaceutics. The Ayurvedic drug formulation is based on what is known as "Pancavidha Kasaaya" concept. According to this concept there are five basic forms of formulation known as 1- 'Swarasa' the expressed juice, 2-'Kalka', a fine paste obtained by grinding fresh or wet grinding dried plant material 3- 'Kwaatha', the decoction, 4- 'Sheeta' or 'Hima', the cold water infusion and 5- 'Faanta', the hot water infusion. Different aspects of their preparation and use have been discussed. Further from the above basic forms, a number of other formulations are derived; a brief description of each of them has been given along with brief outlines of drug formulations meant for specific routes. The third part of the review is devoted to discussion of influence of different factors on the expression of pharmacological activity.


Vaghasiya Y.K.,Saurashtra University | Shukla V.J.,Gujarat Ayurved University | Chanda S.V.,Saurashtra University
Journal of Pharmacology and Toxicology | Year: 2010

Acute oral toxicity of methanol extract of Pluchea arguta Boiss was evaluated in Swiss albino mice of both sexes. In this study mice were administered orally with dosages of 1000, 3000 and 6000 mg kg-1 b.wt. of methanol extract of P. arguta extract. Mortality, signs of toxicity, body weight, food and water consumption, haematological and gross behaviour was observed for 7 days post treatment of P. arguta extract. No mortality, signs of toxicity and abnormalities in gross behaviour were observed. In addition, no significant differences were noticed in the body and organ weights between the control and treated groups of both sexes. The methanol extract of P. arguta is nontoxic and safe by oral intake. © 2011 Academic Journals Inc.


Sharma H.,Ohio State University | Chandola H.M.,Gujarat Ayurved University
Journal of Alternative and Complementary Medicine | Year: 2011

Background: Obesity, metabolic syndrome, and diabetes mellitus are increasing to epidemic proportions globally. Prameha is a syndrome described in the ancient Ayurvedic texts that includes clinical conditions involved in obesity, prediabetes, diabetes mellitus, and metabolic syndrome. Materials and methods: Various dietary, lifestyle, and psychologic factors are involved in the etiology of Prameha, particularly in relation to disturbances in fat and carbohydrate metabolism. Results: The Ayurvedic management of Prameha emphasizes dietary and lifestyle recommendations and herbal preparations, in accordance with the psychophysiologic constitution of the patient. Ayurveda also addresses the management of psychologic factors that contribute to the development of Prameha. Ayurvedic treatment known as Apatarpana (balanced diet with restricted calories) and Santarpana (highly nutritious, high-calorie diet intended to increase weight) are recommended for patients with type 2 and type 1 diabetes, respectively. Various Ayurvedic herbs and herbomineral formulations are utilized, based on the stage and type of disease as well as the psychophysiologic constitution of the patient. A large body of research has been conducted on these Ayurvedic herbs. Conclusions: Integrating the theory and modalities of Ayurveda in the management of these disorders may prove to be beneficial. © 2011 Mary Ann Liebert, Inc.

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