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Reggio nell'Emilia, Italy

Cucinella G.,University of Palermo | Granese R.,Messina University | Calagna G.,University of Palermo | Svelato A.,University of Palermo | And 5 more authors.
Archives of Gynecology and Obstetrics

Objective: The primary aim of the study was to analyze the endometrioma recurrence rate in patients who underwent laparoscopic excision followed by postoperative long-term regimen of oral contraceptives (OCs). Materials and methods: 168 patients who underwent a conservative laparoscopic surgery for endometrioma, during the period between September 2009 and August 2010 in three university hospitals were studied. A long-term OCs therapy was offered to all women following surgery. Patients were randomly divided into three groups according to different progestins used (desogestrel, gestodene, dienogest). Women who refused a postoperative hormonal therapy served as control. Follow-up visits and transvaginal scan were planned at 1, 3, 6, 12, and 24 months after surgery. All patients who showed an ultrasound persistence of the endometrioma at 1 month follow-up were excluded from clinical analysis. Results: Of the 168 patients, 131 completed the 24 months follow-up. Endometrioma recurrence was found in 21 (12.5 %) of all patients, it was unilateral in 17 cases while bilateral in 4 cases. The rate of recurrent endometrioma was statistically significant in non-users compared to the long-term OCs treated patients. Conclusion: The current data suggest the usefulness of long-term OCs regimen after conservative surgery for the prevention of ovarian endometrioma recurrence. As a statistical significant difference could not be observed between OCs groups, further study on the individual molecules is required in order to really understand the effect of each of them. © 2013 Springer-Verlag Berlin Heidelberg. Source

Tonni G.,Guastalla Civil Hospital
Journal of Diagnostic Medical Sonography

This article focuses on the sonographic examination technique for evaluation of intracranial translucencies during the first trimester scan. Appropriate knowledge of the sonographic landmarks is the most important factor for evaluating normal as well as abnormal brain structure, and this examination may enable detection of open spina bifida at an early stage of fetal development. © The Author(s) 2013. Source

Menezes G.A.,Iguacu University | Araujo Junior E.,Federal University of Sao Paulo | Lopes J.,Pontifical Catholic University of Rio de Janeiro | Belmonte S.,Pontifical Catholic University of Rio de Janeiro | And 2 more authors.
Journal of Obstetrics and Gynaecology Research

Agnathia–otocephaly or agnathia-sinotia-microstomy syndrome is the most severe malformation affecting the first branchial arch. It is a rare congenital anomaly characterized by absence of the lower jaw and abnormal ear positioning. Prenatal diagnosis is possible on conventional 2-D ultrasound in the second trimester. Three-dimensional ultrasound enhances detection of abnormal facial phenotype, especially in surface rendering mode. In addition, 3-D volume datasets are used to produce a physical model of the anomaly. We present a case of second trimester ultrasound diagnosis of agnathia–otocephaly associated with limb deformities. A physical model produced using 3-D ultrasound volume datasets facilitated better understanding of this congenital malformation, and improvement of parental counselling and management by the multispecialist team. © 2016 Japan Society of Obstetrics and Gynecology Source

Tonni G.,Guastalla Civil Hospital | Tonni G.,Federal University of Sao Paulo | Martins W.P.,University of Sao Paulo | Araujo Junior E.,Federal University of Sao Paulo
Ultrasound in Medicine and Biology

The use of 3-D ultrasound in obstetrics has undergone dramatic development over the past 20years. Since the first publications on this application in clinical practice, several 3-D ultrasound techniques and rendering modes have been proposed and applied to the study of fetal brain, face and cardiac anatomy. In addition, 3-D ultrasound has improved calculations of the volume of fetal organs and limbs and estimations of fetal birth weight. And furthermore, angiographic patterns of fetal organs and the placenta have been assessed using 3-D power Doppler ultrasound quantification. In this review, we aim to summarize current evidence on the clinical relevance of these methodologies and their application in obstetric practice. © 2015 World Federation for Ultrasound in Medicine & Biology. Source

Cucinella G.,University of Palermo | Calagna G.,University of Palermo | Rotolo S.,University of Palermo | Granese R.,Messina University | And 3 more authors.
Gynecologic and Obstetric Investigation

An electronic search concerning the surgical approach in cases of interstitial pregnancy from January 2000 to May 2013 has been carried out. Fifty three studies have been retrieved and included for statistical analysis. Conservative and radical surgical treatments in 354 cases of interstitial pregnancy are extensively described. Hemostatic techniques have been reported as well as clinical criteria for the medical approach. Surgical outcome in conservative versus radical treatment were similar. When hemostatic techniques were used, lower blood losses and lower operative times were recorded. Conversion to laparotomy involved difficulties in hemostasis and the presence of persistent or multiple adhesions. Laparoscopic injection of vasopressin into the myometrium below the cornual mass was the preferred approach. © 2014 S. Karger AG, Basel. Source

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