Guangxi Yulin Orthopedic Hospital

Yulin, China

Guangxi Yulin Orthopedic Hospital

Yulin, China

Time filter

Source Type

Chen T.,Guangxi Yulin Orthopedic Hospital | Li G.-B.,Guangxi Yulin Orthopedic Hospital | Liang K.-Y.,Guangxi Yulin Orthopedic Hospital | Jia S.-Q.,Guangxi Yulin Orthopedic Hospital
Chinese Journal of Tissue Engineering Research | Year: 2013

BACKGROUND: Related clinical studies have shown that there are different levels of characteristic changes in spine-pelvis sagittal balance parameters in patients with spine-related degenerative diseases. OBJECTIVE: To investigate the effect of spine-pelvis sagittal balance parameters on the treatment of spinal diseases. METHODS: The measurement parameters and measurement methods of spine-pelvis sagittal balance, as well as the quantization and important parameters of spine-pelvis sagittal balance in the diagnosis and treatment of adult spinal diseases were analyzed. The relationship between parameters and the quality of life of the patients was analyzed. The effect on spinal diseases after correction and the role of spine-pelvis sagittal balance in the treatment of spinal disorders were evaluated. RESULTS AND CONCLUSION: Spinal sagittal morphology was closely related to the pelvic parameters, and the pelvic parameters can also be used for the spinal sagittal curves typing. There is a significant statistical correlation between pelvis sagittal parameters and spinal sagittal parameters. The spine-pelvis sagittal balance parameters are the important indicators for the evaluation of spinal diseases and treatment and prognosis, and studies addressing pelvis and spine morphological parameters should be included when evaluating the changes of spine-pelvis sagittal balance.


Chen T.,Guangxi Yulin Orthopedic Hospital | Li G.-B.,Guangxi Yulin Orthopedic Hospital | Liang K.-Y.,Guangxi Yulin Orthopedic Hospital | Jia S.-Q.,Guangxi Yulin Orthopedic Hospital
Chinese Journal of Tissue Engineering Research | Year: 2013

Background: Studies have shown that lumbar disc degeneration is closely related to genes. Objective: To explore the relationship between COL9A2 gene single nucleotide polymorphisms (rsl2722877, rs3737820 and rs209914) and lumbar disc degeneration. Methods: 280 patients with lumbar degenerative disc disease were selected, and 268 age- and sex-matched patients without lumbar degenerative disc disease were selected as control group. All the patients came from Guangxi Zhuang Autonomous Region. The blood samples were collected from the patients with lumbar degenerative disc disease and without lumbar degenerative disc disease to extract the genomic DNA and to design PCR primers and TaqMan probe for the rsl2722877 rs3737820 and rs209914 sites of COL9A2 gene. The allele frequency and genotype frequency were analyzed with SPSS17.0 software. Results and Conclusion: The differences of genotype and the allele frequency distribution of rsl2722877 rs3737820 and rs209914 sites were statistically significant (P < 0.05). The COL9A2 gene single nucleotide polymorphisms rsl2722877, rs3737820 and rs209914 were closely related with susceptibility of lumbar degenerative disc disease in Guangxi Zhuang population.

Loading Guangxi Yulin Orthopedic Hospital collaborators
Loading Guangxi Yulin Orthopedic Hospital collaborators