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Nanning, China

Wu Y.-Q.,Guangxi Minzu Hospital | Pan J.-S.,Guangxi Minzu Hospital | Zhao W.-Q.,Guangxi Minzu Hospital
Journal of Clinical Dermatology

Objective: To evaluate the curative effect of moisture and softening cream (MSC) combined with compound flumetasone ointment for chronic eczema, and recurrence rates after treatment.Methods: One hundred and twenty-five cases of chronic eczema were randomly divided into two groups, the pilot group (63 cases) and control group (62 cases). MSC was applied directly to the lesions of the pilot group for 5 mm, followed by external application of compound flumetasone ointment The control group received compound flumetasone ointment only. Both of the two groups received treatments twice a day (morning and evening) for 3 weeks. After the treatment, the pilot group continued to receive external application of MSC for 2 wccka. Follow-up was conductcd bcfore and after thc trcatment at the 1, 2 and 3 week to evaluated curative effects. Recurrence rates were also evaluated at the 5 and 8 week after the treatment.Results: After 3 week's treatment, EASI of two groups were both decreased evidently, and the pilot group was significantly higher than that of the control group. The effective and recovery rntes of the pilot group were significantly higher than thnse of the control group (P<0.01). After 4 and 8 weeks of withdrawal, recurrence rates of the pilot group were both significantly lower than that of the control. (P<0.05, P<0.01).Conclusion: MSC combined with compound flumetasene ointment has a positive curative effect on the treatment of chronic eczema. Compared with using compound flumetasone ointment alone, it has higher curative effect and lower recurrence rate. And it can also repair the skin barrier, reduce the dose of corticoateroid nod avoid the side effects, which worth popularizing. Source

Huang Y.,Guangxi Minzu Hospital | Huang J.,Guangxi Minzu Hospital | Lan H.,Guangxi Minzu Hospital | Zhao G.,Guangxi Minzu Hospital | Huang C.,Guangxi Minzu Hospital

Objective: Previous studies regarding the association between parental smoking and the risk of childhood brain tumors (CBT) have reported inconsistent results. We performed a meta-analysis to summarize evidence on this association and to quantify the potential dose-response relationship. Methods: A systematic literature search was conducted in the Medline and Embase databases. The summary relative risks (RRs) with 95% confidence intervals (CIs) were calculated. Dose-response meta-analysis was also performed for studies that reported categorical risk estimates for a series of smoking exposure levels. Results: A total of 17 studies fulfilled the inclusion criteria. In the meta-analyses, the summary RRs (95% CIs) of CBT for maternal smoking during pregnancy, paternal smoking during pregnancy, maternal smoking before pregnancy, and paternal smoking before pregnancy were 0.96 (0.86-1.07), 1.09 (0.97-1.22), 0.93 (0.85-1.00), and 1.09 (1.00-1.20), respectively. Dose-response meta-analysis also showed no significant association between parental smoking and the risk of CBT. Conclusions: Findings from our meta-analysis indicate that parental smoking may not be associated with a risk of CBT. © 2014 Huang et al. Source

Huang Y.,Guangxi Minzu Hospital | Li G.,Guangxi Minzu Hospital | Lan H.,Guangxi Minzu Hospital | Zhao G.,Guangxi Minzu Hospital | Huang C.,Guangxi Minzu Hospital
JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Studies investigating the association between the intron 16 insertion/deletion (I/D) polymorphism (rs4646994) in the angiotensin-converting enzyme (ACE) gene and risk of intracerebral hemorrhage (ICH) have reported conflicting results. We here performed a meta-analysis based on the evidence currently available from the literature to make a more precise estimation of this relationship. Published literature from the National Library of Medline and Embase databases were retrieved. Odds ratios (OR) and 95% confidence limits (CLs) were calculated in fixed- or random-effects models when appropriate. Subgroup analyses were performed by race. This meta-analysis included six case-control studies, which included 744 ICH cases and 1411 controls. The combined results based on all studies showed that ICH cases had a significantly lower frequency of ID genotype (OR (codominant model) = 0.43, 95% CL = 0.22, 0.84, p = 0.01). In the subgroup analysis by race, we found that ICH cases had a significantly lower frequency of II genotype in Asians (OR (recessive model) = 0.50, 95% CL = 0.38, 0.66, p > 0.001; OR (codominant model) = 0.25, 95% CL = 0.09, 0.71, p = 0.009). In conclusion, our meta-analysis suggests that ACE I/D polymorphisms are associated with ICH, especially in Asians. © The Author(s) 2014. Source

Su H.-Q.,Guangxi Minzu Hospital | Zhuang X.-Q.,Guangxi Minzu Hospital | Bai Y.,Guangxi Minzu Hospital | Ye H.-H.,Guangxi Minzu Hospital | And 5 more authors.
Journal of Medical Ultrasonics

Purpose: Explore the value of ultrasonography for observation of early healing of humeral shaft fractures. Methods: Sixty-five humeral shaft fracture patients were recruited. They were examined sonographically with color Doppler ultrasonography (CDU) and/or power Doppler ultrasonography (PDU) during the 1st week, 2nd week, 3rd week, 4th week, 9th week, and 15th week after the initial surgical procedure of internal fixation. Formation of callus consolidation and the resistance indexes (RI) of blood flow in different durations were compared between the good healing group and bad healing (delayed fracture healing or nonunion) group. Results: Ultrasound showed that 59 patients had good fracture healing. Within the 2nd and 4th week after surgery, the RI decreased over time (P < 0.05) and color Doppler flow imaging (CDFI/PDU) grading ranged from II to III. Six patients had bad fracture healing (delayed healing or nonunion). Insufficient or absent blood flow signals demonstrated that no callus was found in and/or around the fracture sites. CDFI grading ranged from 0 to I. There was significant difference compared with the good healing group (P < 0.05). Conclusion: CDFI/PDU is an easy, painless, and effective method for predicting the prognosis of humeral shaft fractures by estimating early healing. © 2013 The Japan Society of Ultrasonics in Medicine. Source

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